scholarly journals (1) Nucleic Acids: their Chemical Properties and Physiological Conduct (2) The Simpler Natural Bases (3) The Chemistry of the Radio-Elements (4) Encyclopédie de Science Chimique Appliquée (5) The Principles of Inorganic Chemistry (6) The Chemistry of Cyanogen Compounds and their Manufacture and Estimation (7) Advanced Inorganic Chemistry (8) Preparations and Exercises in Inorganic Chemistry (9) A Manual of Chemistry: Theoretical and Practical, Inorganic and Organic

Nature ◽  
1915 ◽  
Vol 95 (2370) ◽  
pp. 116-117
Author(s):  
T. M. L.
2021 ◽  
Author(s):  
David Dayanidhi Paul Elisa Sundar ◽  
Vaidyanathan Ganesan

Studies on the binding interaction of small molecules and nucleic acids have been explored for their biological applications. With excellent photophysical/chemical properties, numerous metal complexes have been studied as structural...


Life ◽  
2020 ◽  
Vol 10 (12) ◽  
pp. 346
Author(s):  
Kevin G Devine ◽  
Sohan Jheeta

Modern terran life uses several essential biopolymers like nucleic acids, proteins and polysaccharides. The nucleic acids, DNA and RNA are arguably life’s most important, acting as the stores and translators of genetic information contained in their base sequences, which ultimately manifest themselves in the amino acid sequences of proteins. But just what is it about their structures; an aromatic heterocyclic base appended to a (five-atom ring) sugar-phosphate backbone that enables them to carry out these functions with such high fidelity? In the past three decades, leading chemists have created in their laboratories synthetic analogues of nucleic acids which differ from their natural counterparts in three key areas as follows: (a) replacement of the phosphate moiety with an uncharged analogue, (b) replacement of the pentose sugars ribose and deoxyribose with alternative acyclic, pentose and hexose derivatives and, finally, (c) replacement of the two heterocyclic base pairs adenine/thymine and guanine/cytosine with non-standard analogues that obey the Watson–Crick pairing rules. This manuscript will examine in detail the physical and chemical properties of these synthetic nucleic acid analogues, in particular on their abilities to serve as conveyors of genetic information. If life exists elsewhere in the universe, will it also use DNA and RNA?


Nature ◽  
1950 ◽  
Vol 166 (4213) ◽  
pp. 170-172
Author(s):  
D. O. JORDAN

2018 ◽  
Vol 20 (1) ◽  
pp. 49-55 ◽  
Author(s):  
Tiago Matos ◽  
Leif Bülow

The needs for purified nucleic acids for preparative and analytical applications have increased constantly, demanding for the development of new and more efficient methods for their recovery and isolation. DNA molecules harbour some intrinsic chemical properties that render them suitable for chromatographic separations. These include a negatively charged phosphate backbone as well as a hydrophobic character originating mainly from the major groove of DNA which exposes the base pairs on the surface of the molecule. In addition, single stranded DNA often allows for a free exposure of the hydrophobic aromatic bases. In this review, multimodal chromatography (MMC) has been evaluated as an alternative tool for complex separations of nucleic acids. MMC embraces more than one kind of interaction between the chromatographic ligand and the target molecules. These resins have often proved superior to conventional single-mode chromatographic materials for DNA isolation, including, e.g., the purification of plasmid DNA from crude cell lysates and for the preparation of DNA fragments before or after a polymerase chain reaction (PCR).


2020 ◽  
Vol 7 (3) ◽  
pp. 161-178
Author(s):  
Jiabai Cai ◽  
Shunxing Li

Nanostructured materials often exhibit unique physical properties, such as fast carrier transport, subwavelength optical waveguiding, and a high surface-area-to-volume ratio. When the size of a material is reduced to nanoscale dimensions, its physical and chemical properties can change dramatically. In addition, nanostructures offer exciting new opportunities for environmental applications. In this review, we aim to provide an up-to-date summary of recent research related to multifunctional TiO2-based inorganic and organic semiconductor nanomaterials, covering both their synthesis and applications. After a brief introduction of the definition and classification of TiO2-based inorganic and organic semiconductor nanomaterial structures, we discuss various application strategies, such as sewage treatment, heavy metal removal, and the oxidation of alcohols to the corresponding aldehydes. In our previous work, we fabricated a variety of TiO2-based hollow spheres using a diverse range of materials from inorganic semiconductors to organic semiconductors and applied these structures as photocatalysts. Further, the development of these nanostructures may enable numerous applications in the field of environmental technology.


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