Patients Suspected of Irritable Bowel Syndrome—Cross-Sectional Study Exploring the Sensitivity of Rome III Criteria in Primary Care

Abstract Background Irritable bowel syndrome (IBS) is one of the commonest diagnosed gastrointestinal disorders (GI) in primary care and gastroenterology practices. This study aimed to explore the prevalence of IBS, and identify associated factors, among university students in Jordan. Methods A cross-sectional study was conducted among students at the Hashemite University in Jordan. A validated, confidential, self-administered data collection questionnaire was used for the collection of personal and sociodemographic data, and the Rome III criteria were used to define IBS. Logistic regression analysis was done to identify factors associated with IBS. Results A total of 198 students participated in the study, of whom 163 had complete data and could be assessed by the Rome III criteria. The age range of the students was 18 to 35 years, and 91 (55.8%) were women. Overall, 26 (16.0%) of the respondents were diagnosed with IBS. Poor sleep (Adjusted Odds Ratio [AOR] 3.9; 95% confidence interval [CI] 1.5-10.4; p<0.01), being married (AOR 7.6; 95% CI 2.0-28.8; p<0.01) and a family history of IBS (AOR 2.9; 95% CI 1.1-7.7; p=0.03) were independently associated with IBS in multivariable analysis. Conclusion IBS was common among otherwise healthy university student in Jordan. Lifestyle factors such as poor sleep appeared to be associated with IBS symptoms.

Download Full-text

Adherence to the pro-inflammatory diet in relation to prevalence of irritable bowel syndrome

Nutrition Journal ◽

10.1186/s12937-019-0487-6 ◽

2019 ◽

Vol 18 (1) ◽

Cited By ~ 2

Author(s):

Asma Salari-Moghaddam ◽

Ammar Hassanzadeh Keshteli ◽

Ahmad Esmaillzadeh ◽

Peyman Adibi

Keyword(s):

Irritable Bowel Syndrome ◽

Cross Sectional Study ◽

Dietary Intakes ◽

Dietary Inflammatory Index ◽

Sectional Study ◽

Cross Sectional ◽

Inflammatory Index ◽

Persian Version ◽

Rome Iii ◽

Irritable Bowel

Abstract Objective There is no prior study that examined the association between nutrient-based dietary inflammatory index (DII) and odds of Irritable Bowel Syndrome (IBS). We examined the association between DII score and odds of IBS and its severity among Iranian adults. Methods In this cross-sectional study, dietary intakes of 3363 Iranian adults were examined using a validated Dish-based 106-item Semi-quantitative Food Frequency Questionnaire (DS-FFQ). DII was calculated based on dietary intakes derived from DS-FFQ. IBS was assessed using a modified Persian version of Rome III questionnaire. Results After adjustment for potential confounders, we found that participants in the highest quintile of DII score had greater chance for IBS compared with those in the lowest quintile (OR: 1.36; 95% CI: 1.03–1.80). By gender, we found a significant association between DII score and IBS among women (OR: 1.41; 95% CI: 1.00–2.00). By BMI status, overweight or obese (BMI ≥ 25 kg/m2) individuals in top quintile of DII score had greater odds for IBS than those in the bottom quintile (OR: 1.64; 95% CI: 1.07–2.53). No significant association was observed between a pro-inflammatory diet and severity of IBS symptoms. Conclusions Consumption of a pro-inflammatory diet was associated with increased odds of IBS, in particular among women and those with BMI ≥ 25 kg/m2.

Download Full-text

Irritable bowel syndrome and its associated factors in adolescents

Paediatrica Indonesiana ◽

10.14238/pi54.6.2014.344-50 ◽

2014 ◽

Vol 54 (6) ◽

pp. 344 ◽

Cited By ~ 2

Author(s):

Lara Fillekes ◽

Ari Prayogo ◽

Fatima Safira Alatas ◽

Badriul Hegar

Keyword(s):

Irritable Bowel Syndrome ◽

Lower Abdominal Pain ◽

Gastrointestinal Disorder ◽

Cross Sectional Study ◽

Rome Iii Criteria ◽

Parental Form ◽

Cross Sectional ◽

Rome Iii ◽

Irritable Bowel ◽

Upper Abdominal

Background Irritable bowel syndrome (IBS) is a commonfunctional gastrointestinal disorder. Increasing prevalences havebeen reported in Asian adolescent populations, however, therehave been few reports on Indonesian adolescents.Objective To investigate the prevalence of IBS and associatedfactors among adolescents in Jakarta.Methods This cross-sectional study included senior high schoolstudents in a district of Jakarta. Students were asked to fillquestionnaires based on the Rome III criteria for IBS. They werethen divided into groups: those with IBS and those without IBS,for the purposes of comparison.Results Out of 232 adolescents (145 females and 87 males) withmean age of 16.06 (SD 0.91) years, 14 (6.0%) had IBS. Elevenout of 14 adolescents with IBS reported upper abdominal painas well as periumbilical/lower abdominal pain. Irritable bowelsyndrome was not associated with socioeconomic status, food anddrink habits, the use of antibiotics, or scolding as a parental formof discipline. However, a significant higher proportion in the useof corporal punishment was found in IBS adolescents comparedto the non-IBS (P=0.034). In addition, stress related to scolding,as a parental form of discipline was more likely to be found in theIBS group than in the non-IBS group (P=0.019).Conclusion The prevalence of IBS among adolescents in Jakartais 6%, which is lower compared to those of other Asian countries.Corporal punishment at home and stress related to scolding athome are found to be associated with IBS.

Download Full-text

Semiquantitative fecal calprotectin test in postinfectious and non-postinfectious irritable bowel syndrome: cross-sectional study

Sao Paulo Medical Journal ◽

10.1590/1516-3180.2014.8000815 ◽

2014 ◽

Vol 133 (4) ◽

pp. 343-349 ◽

Cited By ~ 5

Author(s):

Liliana-Elisabeta David ◽

Teodora Surdea-Blaga ◽

Dan-Lucian Dumitrascu

Keyword(s):

Irritable Bowel Syndrome ◽

Intestinal Inflammation ◽

Fecal Calprotectin ◽

Cross Sectional Study ◽

Positive Test ◽

Sectional Study ◽

Cross Sectional ◽

Bowel Diseases ◽

Rome Iii ◽

Irritable Bowel

CONTEXT AND OBJECTIVE:The presence of a certain degree of inflammation in the gut wall is now accepted in irritable bowel syndrome (IBS). Fecal calprotectin is considered to be a reliable test for detecting intestinal inflammation. Our aim was to assess the presence of inflammation in postinfectious IBS (PI-IBS), compared with non-postinfectious IBS (NPI-IBS). A secondary objective was to determine the usefulness of a rapid fecal calprotectin test in inflammatory bowel diseases (IBD).DESIGN AND SETTING:This was a cross-sectional study. Patients with IBS and IBD at a single tertiary gastroenterology center were prospectively included in this study.METHODS:116 patients with Rome III IBS score (76 females; 48 ± 12 years) were investigated; 24 patients (15 females) had PI-IBS. Intestinal inflammation was assessed using the semiquantitative fecal calprotectin test. The results were expressed as T1, T2 or T3 according to the severity of inflammation (< 15 μg/g; 15-60 μg/g; > 60 μg/g). Using the same test, we evaluated 20 patients with IBD (12 males; 47 ± 13 years).RESULTS:None of the patients with IBS had a T2 or T3 positive test. Among PI-IBS patients, 33% had a T1 positive test. Among NPI-IBS patients, 9.8% had a T1 positive test, which was significantly different to PI-IBS. The calprotectin test was positive in all IBD patients: 80% with T3, 10% with T2 and 10% with T1.CONCLUSIONS:Using a semiquantitative test for fecal calprotectin, positive tests were more frequent in PI-IBS patients than in NPI-IBS patients.

Download Full-text

Is body mass index associated with symptom severity and health-related quality of life in irritable bowel syndrome? A cross-sectional study

BMJ Open ◽

10.1136/bmjopen-2017-019453 ◽

2018 ◽

Vol 8 (10) ◽

pp. e019453 ◽

Cited By ~ 1

Author(s):

Yuanjun Dong ◽

Sabrina Berens ◽

Wolfgang Eich ◽

Rainer Schaefert ◽

Jonas Tesarz

Keyword(s):

Mental Health ◽

Physical Health ◽

Symptom Severity ◽

Cross Sectional Study ◽

Sectional Study ◽

Rome Iii Criteria ◽

Cross Sectional ◽

Rome Iii ◽

Irritable Bowel

ObjectiveThe aim of this study was to describe the body mass index (BMI) distribution in patients with irritable bowel syndrome (IBS) based on the Rome III criteria and to evaluate the association of BMI with symptom severity and quality of life (QOL).MethodsA cross-sectional study was carried out in patients visiting our outpatient functional gastrointestinal disorders specialty clinic. IBS diagnosis was made based on Rome III criteria. IBS symptom severity was investigated using the IBS severity score system. QOL was assessed using the Short Form 36 Health Survey, which consists of physical health and mental health.Results366 patients (252 women) who fulfilled Rome III criteria and provided complete BMI data (23.90±5.22 kg/m2) were included. Overall, 59.0% of patients with IBS were in the normal weight range, 30.3% were overweight or obese, and 10.7% were underweight. Both physical and mental health decreased significantly with the severity of symptoms (all p<0.01), while controlling for several covariates (age, gender, family status, education status and IBS subtypes). Obesity and symptom severity (β=−0.177,△R2=0.037, p<0.01; β=−0.387,△R2=0.147, p<0.01) were significant negative factors that influencing physical health. Symptom severity (β=−0.301,△R2=0.084, p<0.01) was significant negative factor that influencing mental health. However, BMI didn’t account for additional variance in mental health (p>0.05).ConclusionBeing overweight is a common phenomenon in patients with IBS regardless of IBS subtype. The association between QOL and symptom severity followed a negative dose-response pattern. Patients with higher BMI, especially obese patients, were more frequently in poor physical health. However, this kind of relationship was not found in BMI and mental health.

Download Full-text

Screening for Celiac Disease in Patients with Irritable Bowel Syndrome Fulfilling Rome III Criteria

Journal of Coloproctology ◽

10.1055/s-0041-1736645 ◽

2021 ◽

Author(s):

Khaldoon Thanoon Al-Abachi

Keyword(s):

Irritable Bowel Syndrome ◽

Celiac Disease ◽

Gastrointestinal Disorder ◽

Cross Sectional Study ◽

Rome Iii Criteria ◽

Positive Serology ◽

Cross Sectional ◽

Rome Iii ◽

The Mean ◽

Irritable Bowel

Abstract Background Irritable bowel syndrome (IBS) is a common functional gastrointestinal disorder. Celiac disease (CD), a treatable autoimmune enteropathy, with varied presentations, may simulate clinically symptoms of IBS. The aim of the present study is to screen for CD in patients with IBS diagnosed based on the Rome III criteria. Patients and Methods A cross-sectional study was conducted at a secondary care gastrointestinal unit in Al-Salam General Hospital in Mosul city, Iraq, from November 2015 to October 2016. All patients fulfilling the Rome III criteria for IBS were screened for CD using antitissue transglutaminase IgA antibodies (anti-tTG). Patients who tested positive were subjected to endoscopic duodenal biopsy to confirm the diagnosis of CD. Results A total of 100 patients were included in the present study (58 female and 42 male), the mean age of the participants was 40.8 years old (standard deviation [SD] ± 11.57). Ten patients (10/100, 10%) tested positive for anti-tTG antibodies. Five of the seropositive patients (5/10, 50%) showed positive biopsy results according to the Marsh classification, 3 of whom having diarrhea, and 2 with constipation. Conclusion Positive serology and biopsy results suggestive of CD are common among patients with IBS. Screening patients with IBS for CD is justified.

Download Full-text