scholarly journals Isolated proteinuria is a risk factor for pre-eclampsia: a retrospective analysis of the maternal and neonatal outcomes in women presenting with isolated gestational proteinuria

2015 ◽  
Vol 36 (1) ◽  
pp. 25-29 ◽  
Author(s):  
S Shinar ◽  
J Asher-Landsberg ◽  
A Schwartz ◽  
M Ram-Weiner ◽  
M J Kupferminc ◽  
...  
Keyword(s):  
Risk Factor ◽  
Retrospective Analysis ◽  
Neonatal Outcomes ◽  
Maternal And Neonatal Outcomes ◽  
Isolated Proteinuria

scholarly journals Maternal and neonatal outcomes of pregnancy in women with chronic hypertension: a retrospective analysis of a national register

2015 ◽  
Vol 94 (12) ◽  
pp. 1337-1345 ◽  
Author(s):  
Kim Broekhuijsen ◽  
Anita C.J. Ravelli ◽  
Josje Langenveld ◽  
Mariëlle G. van Pampus ◽  
Paul P. van den Berg ◽  
...  
Keyword(s):  
Retrospective Analysis ◽  
Neonatal Outcomes ◽  
Chronic Hypertension ◽  
National Register ◽  
Maternal And Neonatal Outcomes

Influence of antepartum hemorrhage on placenta previa: A multi-center, retrospective cohort study

2020 ◽  
Author(s):  
Wenjie Qing ◽  
Linda Li ◽  
Alyssia Venna ◽  
Jie Zhou
Keyword(s):  
Risk Factor ◽  
Neonatal Intensive Care ◽  
Independent Risk Factor ◽  
Placenta Previa ◽  
Perinatal Outcomes ◽  
Neonatal Outcomes ◽  
Life Threatening ◽  
Gestational Week ◽  
Maternal And Neonatal Outcomes ◽  
The Relationship

Abstract BACKGROUND Placenta previa can be a serious, life-threatening obstetric complication that causes painless but potentially catastrophic bleeding. It is unclear as to whether the frequency of antepartum hemorrhage (APH) relative to the specific gestational week in placenta previa will lead to negative perinatal outcomes. The purpose of the present study was to determine the relationship between APH and gestational week number, and to ascertain the different perinatal outcomes in women with placenta previa. METHODS This was a multi-center, retrospective study in which we enrolled all women with placenta previa between October of 2015 and September of 2018. Patients with placenta previa were divided into two groups: women with APH and women without APH. RESULTS A total of 247 patients were included in this study: 121 women with APH and 126 women without. The incidence of APH was 49.0% (121/247). The mean bleeding frequency was 2.2 ± 1.3 (mean ± SD), with the majority having experienced a one-time bleeding episode (36.4%, 44/121), followed by 26.4% with 2 episodes (32/121), and 23.1% with 3 (28/121). The APH was distinct in every gestational-week category, with bleeding occurring at 31.4 ± 3.3 weeks, ranging from 24 to 37 gestational weeks. The incidence of bleeding varied from 2.6–14.6%, with the highest incidence at 32 gestational weeks. Patients categorized as having complete placental coverage included a greater number of women experiencing bleeding than women who did not bleed (72.9% vs 47.4%, P < 0.001), indicating that a complete placenta was an independent risk factor for APH (odds rations [OR], 4.17; 95% confidence interval [CI], 1.805–9.634). In addition, although APH did not augment the rates of hysterectomy (6.6% vs 7.1%, P = 0.869), it was associated with critical neonatal outcomes that included lower weight, lower Apgar score at 1 minute, preterm age, and more frequent neonatal intensive care unit admissions (P < 0.05). CONCLUSIONS The gestational week and frequency of each APH varied in patients with placenta previa and might result in an increase in adverse maternal and neonatal outcomes. The 32nd gestational week appeared to be the most precarious time—exhibiting the highest incidence of bleeding—and we consider complete placenta previa to be an independent risk factor for APH.

scholarly journals Alternative antimicrobials for prophylaxis of the Group B Streptococcus maternal-fetal disease

2020 ◽  
Vol 14 (06) ◽  
pp. 664-668
Author(s):  
Vicente Sperb Antonello ◽  
Jessica Dallé ◽  
Emilly Dall'Oglio ◽  
Suelyn Ramos ◽  
Felipe Bassols ◽  
...  
Keyword(s):  
Risk Factor ◽  
Antibiotic Prophylaxis ◽  
Pregnant Women ◽  
Neonatal Infection ◽  
Optimal Choice ◽  
Neonatal Outcomes ◽  
Prophylactic Regimen ◽  
First Choice ◽  
Significant Difference ◽  
Maternal And Neonatal Outcomes

Introduction: GBS colonization is an important risk factor for maternal and neonatal infection morbidity and mortality. Intrapartum antibiotics may prevent vertical transmission of GBS from colonized mothers to their babies. The objective of this study was to evaluate the effectiveness of cefazolin prophylactic regimen for GBS disease, comparing it to the established penicillin-based protocols, given the opportunity provided by the temporary unavailability of first-choice antibiotics in Brazil. Methodology: A retrospective analysis was conducted at the Hospital Femina Obstetrics Service between January and December 2015. Ninety-eight pregnant women received standard penicillin (70 patients) or ampicillin (28 patients) antibiotic prophylaxis, and 251 pregnant women received an alternative prophylaxis with cefazolin during the study period. Risk factor, Maternal and neonatal outcomes were evaluated and compared between groups. Results: No significant difference was found in maternal (RR = 0.71; IC 95%:0.30-1.68; p = 0.709) and neonatal (RR = 0.84; IC 95%:0.61-1.15; p = 0.271) outcomes between those patients using the alternative antibiotic prophylaxis in comparison to the standard antibiotics, with the dependent variable of maternal and neonatal outcomes grouped and controlled for potential confounding variables. Conclusions: The antibiotics used as alternatives to penicillin and ampicillin for the prevention of maternal-fetal GBS disease are poorly studied, and this study indicate that cefazolin can be an optimal choice, offering safety in the use of this antibiotic in situations where penicillins are contraindicated or unavailable.

Advanced Maternal Age and Adverse Maternal and Neonatal Outcomes in Pregnant Women

2020 ◽  
Vol 16 ◽  
Author(s):  
Reza Omani-Samani ◽  
Saman Maroufizadeh ◽  
Nafise Saedi ◽  
Nasim Shokouhi ◽  
Arezoo Esmailzadeh ◽  
...  
Keyword(s):  
Birth Weight ◽  
Preterm Birth ◽  
Low Birth Weight ◽  
Cesarean Section ◽  
Pregnant Women ◽  
Maternal Age ◽  
Unwanted Pregnancy ◽  
Advanced Maternal Age ◽  
Neonatal Outcomes ◽  
Maternal And Neonatal Outcomes

Background: Advanced maternal age is an important predictor for maternal and neonatal outcomes such as maternal mortality, low birth weight, stillbirth, preterm birth, cesarean section and preeclampsia. Objective: To determine the association of advanced maternal age and adverse maternal and neonatal outcomes in Iranian pregnant women. Methods: In this hospital-based cross-sectional study, 5117 pregnant women from 103 hospitals in Tehran, Iran, were participated in the study in 2015. The required data were gathered from hospitals which equipped to the department of obstetrics and gynecology. Advanced maternal age was considered as an independent variable and unwanted pregnancy, preeclampsia, preterm birth, cesarean section and low birth weight were considered as interested outcomes. Results: In our study, the prevalence of advanced maternal age was 12.08%. Advanced maternal age was significantly associated with higher risk of unwanted pregnancy (OR: 1.39, 95% CI: 1.12-1.73), preterm birth (OR: 1.75, 95% CI: 1.28- 2.39) and cesarean section (OR: 1.34, 95% CI: 1.03-1.74). In our study, there was no significant relationship between advanced maternal age and preeclampsia but this relationship could be clinically important (OR: 1.48, 95% CI: 0.99-2.20, P=0.052), and there is no significant relationship between advanced maternal age and low birth weight (OR: 1.08, 95% CI: 0.67-1.74, P=0.736). Conclusion: Advanced maternal age is associated with higher risk of unintended pregnancy, preterm birth and cesarean section but our findings did not support advanced maternal age as a risk factor associated with low birth weight.

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