Histone deacetylase 6 regulates the immunosuppressive properties of cancer-associated fibroblasts in breast cancer through the STAT3–COX2-dependent pathway

Oncogene ◽  
2018 ◽  
Vol 37 (45) ◽  
pp. 5952-5966 ◽  
Author(s):  
Ang Li ◽  
Ping Chen ◽  
Ye Leng ◽  
Jiuhong Kang
Keyword(s):  
Breast Cancer ◽  
Histone Deacetylase ◽  
Cancer Associated Fibroblasts ◽  
Histone Deacetylase 6 ◽  
Dependent Pathway

Abstract 5186: Discovery of a novel histone deacetylase 6 inhibitor that kills drug-resistant breast cancer

2019 ◽  
Author(s):  
Catríona Dowling ◽  
Eugene Dillion ◽  
Michael Hemann ◽  
Gerard Cagney ◽  
Anthony Letai ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Histone Deacetylase ◽  
Drug Resistant ◽  
Histone Deacetylase 6

Abstract 5186: Discovery of a novel histone deacetylase 6 inhibitor that kills drug-resistant breast cancer

2019 ◽  
Author(s):  
Catríona Dowling ◽  
Eugene Dillion ◽  
Michael Hemann ◽  
Gerard Cagney ◽  
Anthony Letai ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Histone Deacetylase ◽  
Drug Resistant ◽  
Histone Deacetylase 6

scholarly journals Histone Deacetylase 6 (HDAC6) Deacetylates Survivin for Its Nuclear Export in Breast Cancer

2012 ◽  
Vol 287 (14) ◽  
pp. 10885-10893 ◽  
Author(s):  
Matthew T. Riolo ◽  
Zachary A. Cooper ◽  
Michael P. Holloway ◽  
Yan Cheng ◽  
Cesario Bianchi ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Histone Deacetylase ◽  
Nuclear Export ◽  
Histone Deacetylase 6

A selenium-containing selective histone deacetylase 6 inhibitor for targeted in vivo breast tumor imaging and therapy

2019 ◽  
Vol 7 (22) ◽  
pp. 3528-3536 ◽  
Author(s):  
Chu Tang ◽  
Yang Du ◽  
Qian Liang ◽  
Zhen Cheng ◽  
Jie Tian
Keyword(s):  
Breast Cancer ◽  
Histone Deacetylase ◽  
Treatment Efficacy ◽  
Breast Tumor ◽  
Tumor Imaging ◽  
Selective Inhibitor ◽  
Biodistribution Study ◽  
Histone Deacetylase 6 ◽  
Antitumor Effects

We have developed a HDAC6-selective inhibitor, SelSA, which can be utilized as a target for the detection and treatment of ERα(+) breast cancer and TNBC. The biodistribution study showed that SelSA can specifically target the breast tumor and display potent antitumor effects in vivo. This result will help to better improve the treatment efficacy against breast cancer.

scholarly journals Association of Estrogen Receptor α and Histone Deacetylase 6 Causes Rapid Deacetylation of Tubulin in Breast Cancer Cells

2009 ◽  
Vol 69 (7) ◽  
pp. 2935-2940 ◽  
Author(s):  
Kotaro Azuma ◽  
Tomohiko Urano ◽  
Kuniko Horie-Inoue ◽  
Shin-ichi Hayashi ◽  
Ryuichi Sakai ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Estrogen Receptor ◽  
Cancer Cells ◽  
Histone Deacetylase ◽  
Breast Cancer Cells ◽  
Estrogen Receptor Α ◽  
Histone Deacetylase 6

Histone deacetylase 6– HDAC6– a new regulator of glucocorticoid receptor-mediated metabolic processes

2010 ◽  
Vol 5 (S 01) ◽  
Author(s):  
R Winkler ◽  
M Clemenz ◽  
M Bloch ◽  
A Foryst-Ludwig ◽  
C Böhm ◽  
...  
Keyword(s):  
Glucocorticoid Receptor ◽  
Histone Deacetylase ◽  
Histone Deacetylase 6 ◽  
Metabolic Processes
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