Confirmation of the absolute configuration of Stachybotrin C using single-crystal X-ray diffraction analysis of its 4-bromobenzyl ether derivative

2018 ◽  
Vol 71 (6) ◽  
pp. 584-591 ◽  
Author(s):  
Yu Kuroda ◽  
Keiko Hasegawa ◽  
Keiichi Noguchi ◽  
Kazuhiro Chiba ◽  
Keiji Hasumi ◽  
...  
Keyword(s):  
Single Crystal ◽  
Diffraction Analysis ◽  
Absolute Configuration ◽  
X Ray Diffraction ◽  
X Ray ◽  
Ether Derivative ◽  
The Absolute

scholarly journals Anti-inflammatory Anthraquinones from the Crinoid Himerometra magnipinna

2015 ◽  
Vol 10 (2) ◽  
pp. 1934578X1501000
Author(s):  
Yen-You Lin ◽  
Su-June Tsai ◽  
Michael Y. Chiang ◽  
Zhi-Hong Wen ◽  
Jui-Hsin Su
Keyword(s):  
Single Crystal ◽  
Diffraction Analysis ◽  
Absolute Configuration ◽  
Spectroscopic Data ◽  
Test Compound ◽  
X Ray Diffraction ◽  
X Ray ◽  
Anti Inflammatory ◽  
Raw264.7 Macrophage

Chemical investigation of a crinoid Himerometra magnipinna has afforded three anthraquinones (1–3), including one new metabolite, (+)-rhodoptilometrin (1). The structures of these compounds were elucidated on the basis of their spectroscopic data and the absolute configuration of 1 was further confirmed by single-crystal X-ray diffraction analysis. In the in vitro anti-inflammatory effects test, compound 2 was found to significantly inhibit the accumulation of the pro-inflammatory iNOS protein of the LPS-stimulated RAW264.7 macrophage cells.

Nd3+ Doped LiCaAIF6 Single Crystal for Scintillator Application

2012 ◽  
Vol 508 ◽  
pp. 224-229 ◽  
Author(s):  
Takayuki Yanagida ◽  
Yoshisuke Futami ◽  
Noriaki Kawaguchi ◽  
Jan Pejchal ◽  
Yutaka Fujimoto ◽  
...  
Keyword(s):  
Single Crystal ◽  
Diffraction Analysis ◽  
Luminescence Spectrum ◽  
Single Phase ◽  
Grown Crystal ◽  
Light Yield ◽  
Transmittance Spectrum ◽  
X Ray Diffraction ◽  
X Ray ◽  
The Absolute

ααΑαNd3+ 0.5% Doped Single Crystal LiCaAlF6 Scintillator Was Grown by the Micro-Pulling down (µ-PD) Method. Powder X-Ray Diffraction Analysis Was Done and the Grown Crystal Was a Single Phase LiCaAlF6. it Was Cut and Polished to the Physical Dimension of 1 × 2 × 7 mm3. in Transmittance Spectrum, Nd3+ 5d-4f Absorption Observed at 175 Nm and the Transmittance Became 80% at Wavelength Longer than 180 Nm. Excited by 160 Nm, Nd3+ 5d-4f Emission Appeared at 180 Nm. X-Ray Induced Radio-Luminescence Spectrum Showed the Similar Feature with the Photoluminescence One. when Coupled with PMT and Irradiated by 241Am α-Ray, the Absolute Light Yield Resulted 100 Ph/5.5 Mev α.

Euryachins A and B, a new type of diterpenoids from Eurya chinensis with potent NO production inhibitory activity

RSC Advances ◽  
2016 ◽  
Vol 6 (89) ◽  
pp. 85958-85961 ◽  
Author(s):  
Jia-Ling Song ◽  
Yao Yuan ◽  
Hai-Bo Tan ◽  
Jie-Wei Wu ◽  
Ri-Ming Huang ◽  
...  
Keyword(s):  
Single Crystal ◽  
Absolute Configuration ◽  
Inhibitory Activity ◽  
No Production ◽  
X Ray Diffraction ◽  
X Ray ◽  
New Type ◽  
The Absolute

Euryachins A (1) and B (2), new typediterpenoid euryamanes, were isolated from the branches of Eurya chinensis. The absolute configuration of 1 was determined by single-crystal X-ray diffraction. Both 1 and 2 exhibited significant NO production inhibitory activity.

scholarly journals Jatroidaine A: a New Tetranortirucallane Type Triterpene from Jatropha multifida

2021 ◽  
Vol 15 (5) ◽  
pp. 408-413
Author(s):  
Fei Li ◽  
Liang Ma ◽  
Jinyuan Zhang ◽  
Xueling Qiao ◽  
Dingshan Zhang ◽  
...  
Keyword(s):  
Single Crystal ◽  
Diffraction Analysis ◽  
Absolute Configuration ◽  
Thioredoxin Reductase ◽  
Spectroscopic Methods ◽  
Significant Activity ◽  
X Ray Diffraction ◽  
X Ray ◽  
Inhibitory Activities ◽  
Jatropha Multifida

Jatroidaine A (1), a new tetranortirucallane-type triterpene, and two known analogues (2−3) were isolated from the leaves and branches of Jatropha multifida. Their structures were fully elucidated by extensive spectroscopic methods and comparison to known compounds. The absolute configuration of 1 was assigned by single-crystal X-ray diffraction analysis. All compounds were evaluated for their anti-inflammatory and thioredoxin reductase (TrxR) inhibitory activities. Unfortunately, no significant activity was observed.

scholarly journals 5α,8α-Epidioxysterols from a Formosan Sponge, Axinyssa sp

2013 ◽  
Vol 8 (11) ◽  
pp. 1934578X1300801
Author(s):  
Tzu-Rong Su ◽  
Kai-Ju Liang ◽  
Michael Y. Chiang ◽  
Mei-Chin Lu ◽  
Yu-Jen Wu ◽  
...  
Keyword(s):  
Single Crystal ◽  
Diffraction Analysis ◽  
Cell Lines ◽  
Cancer Cell ◽  
Absolute Configuration ◽  
Cancer Cell Lines ◽  
Spectroscopic Methods ◽  
X Ray Diffraction ◽  
X Ray ◽  
First Time

One new 5α,8α-epidioxysterol, 3-acetylaxinysterol (1), along with one known sterol, axinysterol (2), were isolated from a Formosan sponge, Axinyssa sp.. The structures of the compounds were determined by spectroscopic methods and the absolute configuration of 2 was further confirmed by single-crystal X-ray diffraction analysis for the first time. Compound 2 exhibited significant cytotoxicity against K562 and Molt 4 cancer cell lines.

scholarly journals Memorial Issue Dedicated to Dr. Howard D. Flack: The Man behind the Flack Parameter

Chemistry ◽  
2021 ◽  
Vol 3 (3) ◽  
pp. 818-820
Author(s):  
Catherine E. Housecroft ◽  
Katharina M. Fromm
Keyword(s):  
Single Crystal ◽  
Absolute Configuration ◽  
Molecular Species ◽  
Crystalline Material ◽  
Special Issue ◽  
X Ray Diffraction ◽  
X Ray ◽  
Memorial Issue ◽  
The Absolute ◽  
Absolute Structure

This Special Issue of Chemistry is dedicated to Dr. Howard D. Flack (1943–2017), a renowned crystallographer who transformed the way in which, by using single crystal X-ray diffraction, we are able to determine the absolute structure of a crystalline material, and thereby determine the absolute configuration of molecular species within the material [...]

scholarly journals Diastereoselective Addition of Diazomethane to Zaluzanin A

2014 ◽  
Vol 9 (6) ◽  
pp. 1934578X1400900 ◽  
Author(s):  
Adriana Ortiz-León ◽  
J. Martín Torres-Valencia ◽  
J. Jesús Manríquez-Torres ◽  
José G. Alvarado-Rodríguez ◽  
Uvaldo Hernández-Balderas ◽  
...  
Keyword(s):  
Diffraction Analysis ◽  
Absolute Configuration ◽  
Sesquiterpene Lactones ◽  
Addition Product ◽  
Vibrational Circular Dichroism ◽  
X Ray Diffraction ◽  
X Ray ◽  
H Nmr ◽  
Diastereoselective Addition ◽  
The Absolute

The diastereoselectivity of diazomethane addition to the conjugated double bond of α,β-unsaturated sesquiterpene lactones was explored using zaluzanin A (1) as a model. Thus, the absolute configuration of 1 was assured by X-ray diffraction analysis including evaluation of Flack and Hooft parameters, and by vibrational circular dichroism spectroscopy of its diacetyl derivative 2, while the absolute configuration of the diazomethane addition product, zaluzanin A pyrazoline (3), was determined by evaluation of the 1H NMR chemical shift changes with respect to 1, and confirmed by X-ray diffraction analysis, again including evaluation of Flack and Hooft parameters.

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