scholarly journals Possible association between SIRT1 single nucleotide polymorphisms and predisposition to antisocial personality traits in Chinese adolescents

2017 ◽  
Vol 7 (1) ◽  
Author(s):  
Hongjuan Chang ◽  
Qiuge Yan ◽  
Jie Tang ◽  
Juan Huang ◽  
Yanmei Zhang ◽  
...  
Keyword(s):  
Single Nucleotide Polymorphisms ◽  
Personality Traits ◽  
Chinese Adolescents ◽  
Nucleotide Polymorphisms ◽  
Antisocial Personality ◽  
Single Nucleotide ◽  
Antisocial Personality Traits

Single Nucleotide Polymorphisms in Thyroid Hormone Transporter Genes MCT8, MCT10 and Deiodinase DIO2 Contribute to Inter-Individual Variance of Executive Functions and Personality Traits

2019 ◽  
Vol 128 (09) ◽  
pp. 573-581
Author(s):  
Jan Christoph Uter ◽  
Ulrike M. Krämer ◽  
Ludger Schöls ◽  
Antoni Rodriguez-Fornells ◽  
Anna Göbel ◽  
...  
Keyword(s):  
Thyroid Hormone ◽  
Single Nucleotide Polymorphisms ◽  
Personality Traits ◽  
Cognitive Functions ◽  
Neuropsychological Test ◽  
Neuropsychological Testing ◽  
Nucleotide Polymorphisms ◽  
Single Nucleotide ◽  
Thyroid Metabolism ◽  
Personality Questionnaires

AbstractThyroid hormones are modulators of cognitive functions, and changes in hormone levels affect intelligence, memory, attention and executive function. Single nucleotide polymorphisms (SNPs) of transporter proteins MCT8, MCT10 and deiodinase 2 (DIO2) influence thyroid metabolism and could therefore contribute to inter-individual variance of cognitive functions. This study investigates the influence of these SNPs using an extensive neuropsychological test battery. 656 healthy participants aged 18–39 years were genotyped for four SNPs: MCT8 (rs5937843 and rs6647476), MCT10 (rs14399) and DIO2 (rs225014) and underwent eleven different neuropsychological tests as well as four personality questionnaires. Test results were compared between homo- and heterozygous carriers and for the X-linked MCT8 additionally between men and women. Personality questionnaires revealed that Risk Seeking was reduced in homozygous T carriers and highest in homozygous C carriers of the DIO2 SNP and that both polymorphisms of MCT8 had an additive effect on Physical Aggression in men. Neuropsychological testing indicated that MCT10 affects nonverbal reasoning abilities, DIO2 influences working memory and verbal fluency and MCT8 influences attention, alertness and planning. This pilot study suggests an influence of polymorphisms in thyroid hormone transporter genes and deiodinase on cognitive domains and personality traits.

Neurological soft signs in Chinese adolescents with antisocial personality traits

2016 ◽  
Vol 243 ◽  
pp. 143-146 ◽  
Author(s):  
Xin Wang ◽  
Lin Cai ◽  
Lingyan Li ◽  
Yanjie Yang ◽  
Shuqiao Yao ◽  
...  
Keyword(s):  
Personality Traits ◽  
Chinese Adolescents ◽  
Antisocial Personality ◽  
Neurological Soft Signs ◽  
Antisocial Personality Traits

scholarly journals An Attempt to Identify Single Nucleotide Polymorphisms Contributing to Possible Relationships between Personality Traits and Oxytocin-Related Genes

2014 ◽  
Vol 69 (1) ◽  
pp. 25-30 ◽  
Author(s):  
Marit Haram ◽  
Martin Tesli ◽  
Ingrid Dieset ◽  
Nils Eiel Steen ◽  
Jan Ivar Røssberg ◽  
...  
Keyword(s):  
Single Nucleotide Polymorphisms ◽  
Personality Traits ◽  
Nucleotide Polymorphisms ◽  
Single Nucleotide

Development of a simple method for the determination of single nucleotide polymorphisms

2010 ◽  
Vol 34 (8) ◽  
pp. S75-S75
Author(s):  
Weifeng Zhu ◽  
Zhuoqi Liu ◽  
Daya Luo ◽  
Xinyao Wu ◽  
Fusheng Wan
Keyword(s):  
Single Nucleotide Polymorphisms ◽  
Nucleotide Polymorphisms ◽  
Simple Method ◽  
Single Nucleotide

Subclinical Sadism and the Dark Triad

2019 ◽  
Vol 40 (3) ◽  
pp. 127-133 ◽  
Author(s):  
Laura K. Johnson ◽  
Rachel A. Plouffe ◽  
Donald H. Saklofske
Keyword(s):  
Factor Analysis ◽  
University Students ◽  
Personality Traits ◽  
Exploratory Factor Analysis ◽  
Convergent Validity ◽  
Dark Triad ◽  
Antisocial Personality ◽  
Factor Solution ◽  
Online Study ◽  
Antisocial Personality Traits

Abstract. The Dark Triad is a constellation of three antisocial personality traits: Machiavellianism, narcissism, and psychopathy. Recently, researchers have introduced a “Dark Tetrad” that includes subclinical sadism, although others suggest considerable overlap between psychopathy and sadism. To clarify the position of sadism within the Dark Triad, an online study was conducted with 615 university students. Exploratory factor analysis revealed that a six-factor solution fit the data best, representing Machiavellianism, psychopathy, physical sadism, verbal sadism, narcissism, and vicarious sadism. Furthermore, convergent validity was supported through sadism’s correlations with the HEXACO personality traits. The results support sadism’s inclusion within the Dark Tetrad as a unique construct but with some conceptual overlap with psychopathy.

Sex Differences in Childhood Associations between DNA Markers and General Cognitive Ability

2007 ◽  
Vol 28 (3) ◽  
pp. 161-164 ◽  
Author(s):  
Rosalind Arden ◽  
Nicole Harlaar ◽  
Robert Plomin
Keyword(s):  
Sex Differences ◽  
Single Nucleotide Polymorphisms ◽  
Cognitive Ability ◽  
Dna Markers ◽  
Community Sample ◽  
Nucleotide Polymorphisms ◽  
General Cognitive Ability ◽  
Single Nucleotide ◽  
The Difference

Abstract. An association between intelligence at age 7 and a set of five single-nucleotide polymorphisms (SNPs) has been identified and replicated. We used this composite SNP set to investigate whether the associations differ between boys and girls for general cognitive ability at ages 2, 3, 4, 7, 9, and 10 years. In a longitudinal community sample of British twins aged 2-10 (n > 4,000 individuals), we found that the SNP set is more strongly associated with intelligence in males than in females at ages 7, 9, and 10 and the difference is significant at 10. If this finding replicates in other studies, these results will constitute the first evidence of the same autosomal genes acting differently on intelligence in the two sexes.

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