scholarly journals Risk factors for the development of esophageal candidiasis among patients in community hospital

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Hideyuki Ogiso ◽  
Seiji Adachi ◽  
Masatoshi Mabuchi ◽  
Yohei Horibe ◽  
Tomohiko Ohno ◽  
...  
Keyword(s):  
Risk Factors ◽  
Gastric Cancer ◽  
Advanced Gastric Cancer ◽  
Community Hospital ◽  
Significant Risk ◽  
Morbidity Rate ◽  
Close Monitoring ◽  
Esophageal Candidiasis ◽  
Grade Ii ◽  
Lifestyle Related Diseases

AbstractThe aim of this study was to clarify risk factors for esophageal candidiasis (EC) in immunocompetent patients in a community hospital. 7736 patients who underwent esophagogastroduodenoscopy at our hospital from April 2012 to July 2018 were enrolled. The relationships between EC and the following factors: age, gender, body mass index, lifestyle, lifestyle-related diseases, medication, and endoscopic findings were analyzed. EC was observed in 184 of 7736 cases (2.4% morbidity rate). Multivariate analysis revealed that significant risk factors for the development of EC were: diabetes mellitus {odds ratio (OR): 1.52}, proton pump inhibitor (PPI) use (OR: 1.69), atrophic gastritis (AG) (OR: 1.60), advanced gastric cancer (OR: 4.66), and gastrectomy (OR: 2.32). When severe EC (Kodsi grade ≥ II) was compared to mild EC (grade I), the most significant risk factors were advanced gastric cancer (OR: 17.6) and gastrectomy (OR: 23.4). When considering the risk of AG and PPI use with EC development, the risk increased as follows: AG (OR: 1.59), PPI use (OR: 2.25), and both (OR: 3.13). PPI use, AG, advanced gastric cancer and post-gastrectomy are critical risk factors for the development of EC. We suggest close monitoring for EC development when PPIs are administered to patients with these factors.

scholarly journals Atrophic Gastritis Predicts Development of Esophageal Candidiasis Among Patients in Community Hospital

2021 ◽  
Author(s):  
Hideyuki Ogiso ◽  
Seiji Adachi ◽  
Masatoshi Mabuchi ◽  
Yohei Horibe ◽  
Tomohiko Ohno ◽  
...  
Keyword(s):  
Risk Factors ◽  
Gastric Cancer ◽  
Atrophic Gastritis ◽  
Advanced Gastric Cancer ◽  
Community Hospital ◽  
Significant Risk ◽  
Morbidity Rate ◽  
Close Monitoring ◽  
Esophageal Candidiasis ◽  
Lifestyle Related Diseases

Abstract Purpose: The aim of this study was to clarify risk factors for esophageal candidiasis (EC) in immunocompetent patients in a community hospital.Methods: 7736 patients who underwent esophagogastroduodenoscopy at our hospital from April 2012 to July 2018 were enrolled. The relationships between EC and the following factors: age, gender, body mass index, lifestyle, lifestyle-related diseases, medication, and endoscopic findings were analyzed.Results: EC was observed in 184 of 7736 cases (2.4% morbidity rate). Multivariate analysis revealed that significant risk factors for the development of EC were: diabetes mellitus {odds ratio (OR): 1.52}, proton pump inhibitor (PPI) use (OR: 1.69), atrophic gastritis (AG) (OR: 1.60), advanced gastric cancer (OR: 4.66), and gastrectomy (OR: 2.32). When severe EC (Kodsi grade ≥ II) was compared to mild EC (grade I), the most significant risk factors were advanced gastric cancer (OR: 17.6) and gastrectomy (OR: 23.4). When considering the risk of AG and PPI use with EC development, the risk increased as follows: AG (OR: 1.59), PPI use (OR: 2.25), and both (OR: 3.13).Conclusions: PPI use and AG are critical risk factors for the development of EC. We suggest close monitoring for EC development when PPIs are administered to patients with AG.

Comorbidity and severity-of-illness risk adjustment for hospital-onset Clostridioides difficile infection using data from the electronic medical record

2020 ◽  
pp. 1-7
Author(s):  
Stephanie M. Cabral ◽  
Katherine E. Goodman ◽  
Natalia Blanco ◽  
Surbhi Leekha ◽  
Larry S. Magder ◽  
...  
Keyword(s):  
Risk Factors ◽  
Risk Factor ◽  
Risk Adjustment ◽  
Community Hospital ◽  
Significant Risk ◽  
Significant Risk Factor ◽  
Bivariate Analysis ◽  
Patient Admissions ◽  
Clostridioides Difficile ◽  
Risk Adjustment Model

Abstract Objective: To determine whether electronically available comorbidities and laboratory values on admission are risk factors for hospital-onset Clostridioides difficile infection (HO-CDI) across multiple institutions and whether they could be used to improve risk adjustment. Patients: All patients at least 18 years of age admitted to 3 hospitals in Maryland between January 1, 2016, and January 1, 2018. Methods: Comorbid conditions were assigned using the Elixhauser comorbidity index. Multivariable log-binomial regression was conducted for each hospital using significant covariates (P < .10) in a bivariate analysis. Standardized infection ratios (SIRs) were computed using current Centers for Disease Control and Prevention (CDC) risk adjustment methodology and with the addition of Elixhauser score and individual comorbidities. Results: At hospital 1, 314 of 48,057 patient admissions (0.65%) had a HO-CDI; 41 of 8,791 patient admissions (0.47%) at community hospital 2 had a HO-CDI; and 75 of 29,211 patient admissions (0.26%) at community hospital 3 had a HO-CDI. In multivariable regression, Elixhauser score was a significant risk factor for HO-CDI at all hospitals when controlling for age, antibiotic use, and antacid use. Abnormal leukocyte level at hospital admission was a significant risk factor at hospital 1 and hospital 2. When Elixhauser score was included in the risk adjustment model, it was statistically significant (P < .01). Compared with the current CDC SIR methodology, the SIR of hospital 1 decreased by 2%, whereas the SIRs of hospitals 2 and 3 increased by 2% and 6%, respectively, but the rankings did not change. Conclusions: Electronically available patient comorbidities are important risk factors for HO-CDI and may improve risk-adjustment methodology.

scholarly journals Tu1327 – Risk Factors of Early and Advanced Gastric Cancer: A 8 Years Population Study in Northern Italy

2019 ◽  
Vol 156 (6) ◽  
pp. S-1027
Author(s):  
Chiara Miraglia ◽  
Ottavia Cavatorta ◽  
Marilisa Franceschi ◽  
Pellegrino Crafa ◽  
Gianluca Baldassarre ◽  
...  
Keyword(s):  
Risk Factors ◽  
Gastric Cancer ◽  
Advanced Gastric Cancer ◽  
Population Study ◽  
Northern Italy

T01.01.24 RISK FACTORS OF EARLY AND ADVANCED GASTRIC CANCER: A 8 YEARS POPULATION STUDY IN NORTHERN ITALY

2020 ◽  
Vol 52 ◽  
pp. S62
Author(s):  
O. Cavatorta ◽  
C. Miraglia ◽  
M. Franceschi ◽  
P. Crafa ◽  
G. Baldassarre ◽  
...  
Keyword(s):  
Risk Factors ◽  
Gastric Cancer ◽  
Advanced Gastric Cancer ◽  
Population Study ◽  
Northern Italy

Impact of preoperative sarcopenia on recurrecnce in gastric cancer surgery.

2016 ◽  
Vol 34 (4_suppl) ◽  
pp. 120-120
Author(s):  
Tsutomu Sato ◽  
Toru Aoyama ◽  
Yukio Maezawa ◽  
Kazuki Kano ◽  
Kenki Segami ◽  
...  
Keyword(s):  
Risk Factors ◽  
Gastric Cancer ◽  
Skeletal Muscle ◽  
Risk Factor ◽  
Muscle Mass ◽  
Significant Risk ◽  
Cancer Surgery ◽  
Pathological Stage ◽  
Gastric Cancer Surgery ◽  
Negative Prognostic Factor

120 Background: Our previous study clarified that morbidity was a negative prognostic factor and sarcopenia defined by of the handgrip strength was a risk factor for the morbidity in gastric cancer surgery. Sarcopenia was reportedly a negative prognostic factor in colorectal cancer, hepatocellular carcinoma and malignant melanoma. This study aimed to evaluate impact of preoperative sarcopenia on recurrence-free survival (RFS) in gastric cancer surgery. Methods: Between May 2011 and June 2013, 256 consecutive primary gastric cancer patients who underwent curative surgery were retrospectively examined. Patients who received neoadjuvant chemotherapy or were diagnosed with pathological stage IV were excluded. Preoperative skeletal muscle mass was evaluated by bioelectrical impedance analysis and was expressed as skeletal muscle index or SMI (muscle mass/height2) by adjusting absolute muscle mass with height. Preoperative muscle function was measured by hand grip strength (HGS). Each cutoff value was determined as the gender-specific lowest 20% of the distribution of each measurement. Univariate and multivariate analyses were preformed to identify risk factors for RFS using a Cox proportional hazards model. Results: Median age (range) was 66 years (37-85 years). Male to female ratio was 168:88. Median follow-up period was 33.4 months. Pathological stage was I in 160, II in 48 and III in 48 patients. Univariate analysis showed that age, adjuvant chemotherapy, pT, pN, histological type, tumor size, total gastrectomy, low SMI and low HGS were significant risk factors for RFS. Multi-variate Cox’s proportional hazard analyses demonstrated that pT (HR 2.76, p = 0.0001), pN (HR 1.375, p = 0.037), histological type (HR 3.46, p = 0.014), low SMI (HR2.17, p = 0.036) were the significant risk factors for RFS. The three-year RFS was 89.1% in the patients with high SMI and 73.2% in those with low SMI (p = 0.007). Conclusions: Low SMI was an independent risk factor for RFS in Stage I-III gastric cancer. Low HGS, a risk factor for morbidity shown in our previous study, was not a risk independent factor for RFS. Preoperative sarcopenia as the short- and long-term outcomes has a value to be tested in the future prospective studies in gastric cancer surgery.

scholarly journals Cumulative incidence, risk factors and prognostic impact of venous thromboembolism in Japanese patients with advanced gastric cancer

2017 ◽  
Vol 47 (10) ◽  
pp. 942-948 ◽  
Author(s):  
Hiroyuki Arai ◽  
Shuichi Hironaka ◽  
Keiko Minashi ◽  
Tadamichi Denda ◽  
Mototsugu Shimokawa ◽  
...  
Keyword(s):  
Risk Factors ◽  
Gastric Cancer ◽  
Venous Thromboembolism ◽  
Advanced Gastric Cancer ◽  
Cumulative Incidence ◽  
Japanese Patients ◽  
Prognostic Impact ◽  
Incidence Risk

scholarly journals Determinants of surgical morbidity in gastric cancer: experience of a single center and literature review

2020 ◽  
Vol 2 (4) ◽  
pp. Press
Author(s):  
Houyem Mansouri ◽  
Ines Zemni ◽  
Mohamed Ali Ayadi ◽  
Ines Ben Safta ◽  
Tarek Ben Dhiab ◽  
...  
Keyword(s):  
Risk Factors ◽  
Gastric Cancer ◽  
Operative Time ◽  
Multiple Logistic Regression Analysis ◽  
Significant Risk ◽  
Surgical Margin ◽  
Length Of Hospital Stay ◽  
Extent Of Resection ◽  
Surgical Morbidity ◽  
Cancer Experience

Background This study aimed to evaluate the severity of intraoperative and post operative complications of gastric cancer surgery and to investigate the predictive factors correlated to surgical morbidity. Methods We included 145 patients operated for gastric cancer. We investigated the risk factors associated with complications, length of hospital stay, operative time, and intraoperative blood transfusion (BT). Significant risk factors were analyzed by multiple logistic regression analysis. Results Postoperative complications occurred in 32 patients (22.1 %) and the rate of major complications was 7.6%. The rate of anastomotic fistula was 6.9% and was correlated to diabetes, tumor size, operative time, surgical margin, and extended lymphadenectomy. The mean risk factors for postoperative morbidity were the presence of comorbidities and ASA score (p = 0.021), intraoperative BT (p = 0.045) and prolonged operative time (p = 0.055). Conclusion surgical morbidity of gastric cancer is correlated to the extent of resection as well as the clinical and histological characteristics.

scholarly journals Neovascular Glaucoma after Diabetic Vitrectomy: Incidence and Risk Factors

2021 ◽  
Vol 62 (7) ◽  
pp. 963-968
Author(s):  
Hyeon Woo Son ◽  
Jung Min Park ◽  
Myeong In Yeom
Keyword(s):  
Risk Factors ◽  
Anterior Segment ◽  
Significant Risk ◽  
Intravitreal Bevacizumab ◽  
Neovascular Glaucoma ◽  
Panretinal Photocoagulation ◽  
Close Monitoring ◽  
Diabetic Vitrectomy ◽  
Postoperative Findings ◽  
High Possibility

Purpose: The prevalence and risk factors of neovascular glaucoma (NVG) after diabetic vitrectomy were evaluated. Methods: This retrospective study included 171 eyes of 141 patients who underwent diabetic vitrectomy in-hospital between March 2013 and July 2019 and were followed for >12 months postoperatively. Regardless of the presence or absence of neovascularization in the anterior segment, all patients received injections of intravitreal bevacizumab during vitrectomy. Patients with preoperative neovascularization in iris (NVI) or angle (NVA) received both intracameral and intravitreal bevacizumab injections. Data were collected regarding baseline demographics, preoperative best-corrected visual acuity, intraocular pressure, hypertension, NVG in the fellow eye, panretinal photocoagulation history, iris and angle neovascularization, and postoperative findings (e.g., rebleeding and residual retinal detachment). Results: In total, 141 patients and 171 eyes were included in the study, and the incidence of postoperative NVG was 5.85% (10 patients). Five patients (27.78%) with preoperative NVI or NVA developed postoperative NVG. Significant risk factors for postoperative NVG were preoperative NVA or NVI (odds ratio [OR] = 16.428, p = 0.003), shorter diabetic duration (OR = 0.853, p = 0.033), and the absence of preoperative panretinal photocoagulation (OR = 0.006, p = 0.035). Conclusions: There is a high possibility of postoperative NVG in patients with preoperative NVI or NVA, a short duration of diabetes, and no preoperative panretinal photocoagulation. In such patients, close monitoring is required after diabetic vitrectomy.

P.01.16 RISK FACTORS OF EARLY AND ADVANCED GASTRIC CANCER: AN 11 YEARS POPULATION STUDY

2019 ◽  
Vol 51 ◽  
pp. e140
Author(s):  
O. Cavatorta ◽  
M. Franceschi ◽  
P. Crafa ◽  
C. Miraglia ◽  
G. Baldassarre ◽  
...  
Keyword(s):  
Risk Factors ◽  
Gastric Cancer ◽  
Advanced Gastric Cancer ◽  
Population Study

scholarly journals Thirty-Day Unplanned Readmission after Total Knee Arthroplasty at a Teaching Community Hospital: Rates, Reasons, and Risk Factors

2019 ◽  
Vol 33 (02) ◽  
pp. 206-212 ◽  
Author(s):  
Kalain K. Workman ◽  
Nathan Angerett ◽  
Ronald Lippe ◽  
Alex Shin ◽  
Scott King
Keyword(s):  
Risk Factors ◽  
Total Knee Arthroplasty ◽  
Knee Arthroplasty ◽  
Community Hospital ◽  
Significant Risk ◽  
The United States ◽  
Administrative Database ◽  
Unplanned Readmission ◽  
Teaching Community ◽  
Total Knee

AbstractUnplanned readmission after total knee arthroplasty (TKA) has an increasing prevalence in the United States. Readmissions are now a metric for hospital quality of care, yet there are mixed results and variables associated with unplanned readmission. In this changing healthcare, it is critical for community healthcare institutions to identify risk factors for unplanned readmissions following TKA. Retrospective chart review and a hospital administrative database query to report causes, demographics, and medical comorbid risk factors result in 30-day readmission after undergoing primary TKA between 2011 and 2016 at a teaching community hospital. This study identified 7,482 primary TKA procedures of which 210 (2.8%) were unplanned readmissions. Gastrointestinal bleed (9.05%) and periprosthetic infection (8.10%) were the most common causes of readmission. Age 65 and older (odds ratio [OR], 1.64; 95% confidence interval [CI], 1.21–2.21; p = 0.0012), male (OR, 1.37; 95% CI, 1.03–1.83; p = 0.0302), length of stay > 3 days (OR, 2.04; 95% CI, 1.45–2.86; p < 0.0001), and discharge to rehab (OR, 2.21; 95% CI, 1.49–3.26; p ≤ 0.0001) were correlated significantly with risk of 30-day readmission. Chronic airway disease (OR, 2.81; 95% CI, 1.54–5.14; p = 0.0008) and obesity (OR, 1.45; 95% CI, 1.006–2.10; p = 0.0463) were significant risk factors. Higher Charlson comorbidity index was not a predictor of time to readmission within 30 days after TKA.

Sign in / Sign up

Export Citation Format

Share Document