scholarly journals Relationship between intraventricular hemorrhage and acute kidney injury in premature infants and its effect on neonatal mortality

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Mountasser M. Al-Mouqdad ◽  
Roya Huseynova ◽  
Thanaa M. Khalil ◽  
Yasmeen S. Asfour ◽  
Suzan S. Asfour

AbstractIntraventricular hemorrhage (IVH) and acute kidney injury (AKI) are important neonatal morbidities in premature infants. This study aimed to investigate the relationship between IVH and AKI in premature infants and whether this association affects the incidence of neonatal mortality. Infants [gestational age (GA) ≤ 32 weeks; birth weight (BW) < 1500 g] were retrospectively evaluated in a large tertiary neonatal intensive care unit. Of 710 premature infants, 268 (37.7%) developed AKI. Infants with IVH were more likely to have AKI than those without IVH. Infants with severe IVH had a higher incidence of AKI than infants with mild IVH. Infants younger than 28 weeks with IVH were more likely to have AKI than those without IVH. An association between IVH grades and AKI stages was observed in the overall study population, in infants with GA < 28 weeks, and in infants with GA between 28 and 32 weeks. Mortality was increased 1.5 times in infants with IVH and AKI compared with that in infants with IVH but without AKI. Furthermore, mortality was increased in infants with IVH and AKI compared with infants without IVH or AKI. This study shows a direct relationship between the severity of IVH and the degree of AKI; both IVH and AKI increase the incidence of neonatal mortality.

2019 ◽  
Vol 65 (5) ◽  
pp. 647-656
Author(s):  
Ali Mazouri ◽  
Mahtab Massahi ◽  
Nasrin Khalesi ◽  
Ladan Younesi asl ◽  
Mandana Kashaki

SUMMARY OBJECTIVE: We measured the level of pH gases in premature infants at birth, and examined the relationship between brain ultrasonography on the third and seventh day after birth. A case-control study conducted at the Neonatal Intensive Care Unit (NICU) of Shahid Akbar Abadi Hospital, Iran, during the years 2016-2017. METHODS: All premature infants who were admitted to NICU were enrolled in the current study. At birth, a blood gas sample was taken from the umbilical cord of the infants. On the third and seventh day after birth, an ultrasound of the brain of each neonate was performed by a radiologist. The umbilical cord was evaluated for blood gases in 72 neonates (mostly boys). RESULTS: Sixty-six newborns had normal sonography, and 16.7% (12 cases) had anomalies. A total of 75% of the 8 infants with intravenous bleeding were girls, which were significantly different from those in the non-hemodynamic group (62.5% male) (P 0.049). However, the type of delivery, mean weight, height, head circumference, the circumference of the chest, and Apgar score did not differ between the two groups. Mean pH, HCO3– and PCO2 in umbilical cord blood gas samples were not significantly different between the two groups with or without intraventricular hemorrhage (IVH). Although it was not related to gender and type of delivery in newborns CONCLUSION: Blood gases do not help in determining the occurrence of IVH in infants. Nevertheless, it is associated with immaturity and fetal age.


2015 ◽  
Vol 69 (1) ◽  
pp. 20-25
Author(s):  
Silvana Naunova-Timovska

Abstract Introduction. Acute kidney injury is a serious condition which damages the kidney as a central mediator of the homeostasis of bodily fluids and electrolytes. It is not a rare problem in the intensive care units, particularly in the neonatal population. Perinatal asphyxia is a common predisposing factor associated with neonatal kidney injury. The aim of this study was to determine the characteristics of acute kidney injury in newborns from neonatal intensive care unit and to explore the association with perinatal asphyxia. Methods. The study was conducted at the Children’s University Hospital in Skopje, R. Macedonia. It was a clinical, prospective study. In the period of two years (January 2013 to December 2014) 29 patients hospitalized at the Neonatal Intensive Care Unit (NICU) with documented neonatal kidney injury were analyzed. Medical data records of admitted neonates with kidney injury were analyzed. The material was statistically analyzed using methods of descriptive statistics. Results. We evaluated 29 neonates with documented acute kidney injury who at the period of 2 years were treated in NICU. The prevalence of kidney injury was 6.4%. Most of involved neonates were born at term (66%). Prerenal injury was evaluated in 80% of cases. Perinatal asphyxia was the most common predisposing factors for kidney injury in our study, revealed in 56% of cases with predominance of term-infants and male gender. Sepsis was present in 44% of cases, prematurity in 34%, and congenital malformation in 27% of cases. Mortality rate was 27.5% and it was higher in patients with assisted ventilation and sepsis. Conclusion. Perinatal asphyxia is a dominant predisposing factor associated with neonatal kidney injury. Often, the occurrence of kidney damage in the neonatal population is multifactorial (more than 40%) and caused by several associated comorbidities


2020 ◽  
Vol 40 (9) ◽  
pp. 1296-1300
Author(s):  
Brittnea Adcock ◽  
Sean Carpenter ◽  
John Bauer ◽  
Peter Giannone ◽  
Aric Schadler ◽  
...  

2015 ◽  
Vol 26 (1) ◽  
pp. 67 ◽  
Author(s):  
Doaa Youssef ◽  
Hadeel Abd-Elrahman ◽  
MohamedM Shehab ◽  
Mohamed Abd-Elrheem

2013 ◽  
Vol 9 (4) ◽  
pp. 323-329 ◽  
Author(s):  
Fatih Bolat ◽  
Serdar Comert ◽  
Guher Bolat ◽  
Oznur Kucuk ◽  
Emrah Can ◽  
...  

2016 ◽  
Vol 22 (2) ◽  
pp. 121-127 ◽  
Author(s):  
Margaret Doyle Settle

There is growing evidence that continuity of nurse caregivers (CNC) has an effect on outcomes for infants admitted to neonatal intensive care units. Using Levine’s conservation model, the relationship of infant acuity and CNC for 50 infants born between 24 and 40 weeks gestation was explored. A statistically significant difference was found between the variable acuity and CNC (F = 8.65, p = .01). Results suggest that high infant acuity is strongly related to high CNC but may be the effect of a third variable. CNC may support the emergence of physiological, structural, and social competencies for convalescing premature infants.


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