Radiological tumour classification across imaging modality and histology

Magnetic resonance imaging (MRI) has become established as an important imaging modality for the clinical management of disease. This is primarily due to the great tissue contrast inherent in magnetic resonance images of normal and diseased organs. Due to the wide availability of high field magnets and the ability to generate large and rapidly switched magnetic field gradients there is growing interest in applying high resolution MRI to obtain microscopic information. This symposium on MRI microscopy highlights new developments that are leading to increased resolution. The application of high resolution MRI to significant problems in developmental biology and cancer biology will illustrate the potential of these techniques.In combination with a growing interest in obtaining high resolution MRI there is also a growing interest in obtaining functional information from MRI. The great success of MRI in clinical applications is due to the inherent contrast obtained from different tissues leading to anatomical information.

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A TEM study of electron tunneling in biological macromolecules

Proceedings, annual meeting, Electron Microscopy Society of America ◽

10.1017/s0424820100125634 ◽

1987 ◽

Vol 45 ◽

pp. 140-141

Author(s):

J. A. Panitz

Keyword(s):

Stark Effect ◽

Electron Tunneling ◽

Imaging Modality ◽

Tunneling Current ◽

Biological Species ◽

Scanning Tunneling ◽

Biological Macromolecules ◽

Flat Surfaces ◽

Virus Particles ◽

Stm Images

Tunneling is a ubiquitous phenomenon. Alpha particle disintegration, the Stark effect, superconductivity in thin films, field-emission, and field-ionization are examples of electron tunneling phenomena. In the scanning tunneling microscope (STM) electron tunneling is used as an imaging modality. STM images of flat surfaces show structure at the atomic level. However, STM images of large biological species deposited onto flat surfaces are disappointing. For example, unstained virus particles imaged in the STM do not resemble their TEM counterparts.It is not clear how an STM image of a biological species is formed. Most biological species are large compared to the nominal electrode separation of ∼ 1nm that is required for electron tunneling. To form an image of a biological species, the tunneling electrodes must be separated by a distance that would normally be too large for a tunneling current to be observed.

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1005: Integrated Petict: A Novel Imaging Modality in Testis Cancer

The Journal of Urology ◽

10.1016/s0022-5347(18)31233-3 ◽

2007 ◽

Vol 177 (4S) ◽

pp. 332-332 ◽

Cited By ~ 1

Author(s):

Joseph R. Sterbis ◽

Stephen A. Brassell ◽

Aaron L. Stack ◽

Marcia C. Javitt ◽

Noah S. Schenkman

Keyword(s):

Imaging Modality ◽

Testis Cancer

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Staging ovarian carcinoma after surgery and chemotherapy: Radiolabelled monoclonal antibodies and their fragments as an imaging modality

Clinical Oncology ◽

10.1016/s0936-6555(05)81236-1 ◽

1991 ◽

Vol 3 ◽

pp. 295-295

Keyword(s):

Monoclonal Antibodies ◽

Ovarian Carcinoma ◽

Imaging Modality ◽

Radiolabelled Monoclonal Antibodies

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181 Echoscintigraphy : A new imaging modality for the assessment of vessel diameters reducing shadowing and blooming artefacts

European Journal of Echocardiography ◽

10.1016/s1525-2167(99)80014-6 ◽

1999 ◽

Vol 1 ◽

pp. S6-S6

Author(s):

K TIEMANN ◽

T SCHLOSSER ◽

H BECHER ◽

D BIMMEL ◽

S KUNTZ ◽

...

Keyword(s):

Imaging Modality

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State-of-the-art aortic imaging: Part II - applications in transcatheter aortic valve replacement and endovascular aortic aneurysm repair

VASA ◽

10.1024/0301-1526/a000324 ◽

2014 ◽

Vol 43 (1) ◽

pp. 6-26 ◽

Cited By ~ 12

Author(s):

Fabian Rengier ◽

Philipp Geisbüsch ◽

Paul Schoenhagen ◽

Matthias Müller-Eschner ◽

Rolf Vosshenrich ◽

...

Keyword(s):

Aortic Valve ◽

Transcatheter Aortic Valve Replacement ◽

Surgical Repair ◽

Imaging Modality ◽

Open Surgical Repair ◽

Cross Sectional ◽

Transcatheter Aortic Valve ◽

Cross Sectional Imaging ◽

Sectional Imaging

Transcatheter aortic valve replacement (TAVR) as well as thoracic and abdominal endovascular aortic repair (TEVAR and EVAR) rely on accurate pre- and postprocedural imaging. This review article discusses the application of imaging, including preprocedural assessment and measurements as well as postprocedural imaging of complications. Furthermore, the exciting perspective of computational fluid dynamics (CFD) based on cross-sectional imaging is presented. TAVR is a minimally invasive alternative for treatment of aortic valve stenosis in patients with high age and multiple comorbidities who cannot undergo traditional open surgical repair. Given the lack of direct visualization during the procedure, pre- and peri-procedural imaging forms an essential part of the intervention. Computed tomography angiography (CTA) is the imaging modality of choice for preprocedural planning. Routine postprocedural follow-up is performed by echocardiography to confirm treatment success and detect complications. EVAR and TEVAR are minimally invasive alternatives to open surgical repair of aortic pathologies. CTA constitutes the preferred imaging modality for both preoperative planning and postoperative follow-up including detection of endoleaks. Magnetic resonance imaging is an excellent alternative to CT for postoperative follow-up, and is especially beneficial for younger patients given the lack of radiation. Ultrasound is applied in screening and postoperative follow-up of abdominal aortic aneurysms, but cross-sectional imaging is required once abnormalities are detected. Contrast-enhanced ultrasound may be as sensitive as CTA in detecting endoleaks.

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Comparative study of ultrasonographic findings with the operative findings of biliary surgery

Journal of Surgical Sciences ◽

10.3329/jss.v22i1.44011 ◽

2020 ◽

Vol 22 (1) ◽

pp. 25-29

Author(s):

Zubayer Ahmad ◽

Mohammad Ali ◽

Kazi lsrat Jahan ◽

ABM Khurshid Alam ◽

G M Morshed

Keyword(s):

Bile Duct ◽

Common Bile Duct ◽

Imaging Modality ◽

False Positive Rate ◽

Gallstone Disease ◽

False Negative ◽

False Negative Rate ◽

Biliary Disease ◽

Biliary Surgery ◽

Operative Findings

Background: Biliary disease is one of the most common surgical problems encountered all over the world. Ultrasound is widely accepted for the diagnosis of biliary system disease. However, it is a highly operator dependent imaging modality and its diagnostic success is also influenced by the situation, such as non-fasting, obesity, intestinal gas. Objective: To compare the ultrasonographic findings with the peroperative findings in biliary surgery. Methods: This prospective study was conducted in General Hospital, comilla between the periods of July 2006 to June 2008 among 300 patients with biliary diseases for which operative treatment is planned. Comparison between sonographic findings with operative findings was performed. Results: Right hypochondriac pain and jaundice were two significant symptoms (93% and 15%). Right hypochondriac tenderness, jaundice and palpable gallbladder were most valuable physical findings (respectively, 40%, 15% and 5%). Out of 252 ultrasonically positive gallbladder, stone were confirmed in 249 cases preoperatively. Sensitivity of USG in diagnosis of gallstone disease was 100%. There was, however, 25% false positive rate detection. Specificity was, however, 75% in this case. USG could demonstrate stone in common bile duct in only 12 out of 30 cases. Sensitivity of the test in diagnosing common bile duct stone was 40%, false negative rate 60%. In the series, ultrasonography sensitivity was 100% in diagnosing stone in cystic duct. USG could detect with relatively good but less sensitivity the presence of chronic cholecystitis (92.3%) and worm inside gallbladder (50%). Conclusion: Ultrasonography is the most important investigation in the diagnosis of biliary disease and a useful test for patients undergoing operative management for planning and anticipating technical difficulties. Journal of Surgical Sciences (2018) Vol. 22 (1): 25-29

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Contrast-Enhanced Ultrasound: a Simple and Effective Tool in Defining a Rapid Diagnostic Work-up for Small Nodules Detected in Cirrhotic Patients during Surveillance

Journal of Gastrointestinal and Liver Diseases ◽

10.15403/jgld.2014.1121.252.chu ◽

2016 ◽

Vol 25 (2) ◽

pp. 205-211 ◽

Cited By ~ 13

Author(s):

Antonio Giorgio ◽

Luca Montesarchio ◽

Piero Gatti ◽

Ferdinando Amendola ◽

Paolo Matteucci ◽

...

Keyword(s):

Predictive Value ◽

Imaging Modality ◽

Dynamic Imaging ◽

Contrast Enhanced Ultrasound ◽

Histologic Diagnosis ◽

Therapeutic Work ◽

Contrast Enhanced ◽

Arterial Vascularization ◽

Cirrhotic Patients ◽

Work Up

Background & Aims: Disappearance of portal blood flow and arterial vascularization is the hallmark of hepatocarcinogenesis. The capability of a dynamic imaging modality detecting arterial hypervascularization of small nodules is crucial to promote a rapid diagnostic and therapeutic work-up improving survival. We aimed to evaluate the capability of CEUS to detect arterial vascularization of ≤ 2 cm HCC nodules arising during surveillance so as to shorten the diagnostic and therapeutic work-up. Methods: From October 2009 to September 2014, among 1757 consecutive cirrhotic patients under surveillance with ultrasound (US), 243 patients had new single nodules 7-20 mm; 229/243 had a conclusive histologic diagnosis and comprised the study group. All patients underwent CEUS followed by enhanced MRI and US guided percutaneous 18G needle core biopsy of the nodules. Of the 229 nodules, 27 were hyperechoic, 171 hypoechoic and 31 isoechoic lesions. Results: The histology results revealed that 199/229 nodules were HCC and 30 were benign. Of 199 HCC, CEUS evidenced arterial hypervascularity in 190 nodules (95.5%) (sensitivity 94.48 %, specificity 100%, PPV 100%, NPV 76.92 %). Of the 39 CEUS arterial-unenhanced nodules, 30 were benign and 9 (23%) were well-differentiated HCC. eMRI showed arterial hypervascularity in 199 nodules (86,9%). Of these, only 193 (97%) were histologically HCCs while 6 were benign (sensitivity: 97%, specificity: 80%, PPV: 97%, NPV: 80%). Conclusions: CEUS has a great capability to detect arterial hypervascularity of small HCC. Because only 4.5% of new nodules escape the demonstration of arterial hyervascularity, CEUS must be performed immediately after conventional US to contrast the malignant fate of small lesions arising in a cirrhotic liver.. Abbreviations: CEUS: contrast-enhanced ultrasound; CT: computed tomography; HCC: hepatocellular carcinoma;MRI: magnetic resonance; NPV: negative predictive value; PPV: positive predictive value; US: ultrasonography.

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The Expanding Role of Echocardiography in Interventional Cardiology

European Cardiology Review ◽

10.15420/ecr.2010.6.2.71 ◽

2010 ◽

Vol 6 (2) ◽

pp. 71 ◽

Cited By ~ 3

Author(s):

Lindsay A Smith ◽

Amit Bhan ◽

Mark J Monaghan ◽

◽

...

Keyword(s):

Interventional Procedures ◽

Imaging Modality ◽

Interventional Cardiology ◽

Design And Technology ◽

Team Approach ◽

Medical Problems ◽

Multidisciplinary Team Approach ◽

Case Selection ◽

Optimal Imaging

Echocardiography provides excellent realtime imaging of the heart, making it the imaging modality of choice immediately before, during and after cardiac interventional procedures. It helps to guide case selection and execution of the intervention, evaluates the effects of the intervention and enables early detection of complications. Advances in the design and technology of medical devices and delivery systems, coupled with demand for alternative non-surgical therapies for common medical problems, have led to an increase in the volume, variety and complexity of non-coronary cardiac interventional procedures performed. Many of these procedures require a multidisciplinary team approach and demand optimal imaging to ensure successful outcomes. The aim of this article is to review the expanding role of echocardiography in non-coronary interventional cardiology in adults.

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Incidence of Cerebral Hemorrhage in Traumatic Patients using Computed Tomography in Tabuk City, Saudi Arabia

International Journal of Innovative Research in Medical Science ◽

10.23958/ijirms/vol05-i10/971 ◽

2020 ◽

Vol 5 (10) ◽

pp. 460-463

Author(s):

Amna Mohamed Ahmed ◽

Towmader Awad ◽

Hajer Yousif ◽

Reem Nahari ◽

Omnia Abdelrhman ◽

...

Keyword(s):

Computed Tomography ◽

Saudi Arabia ◽

Head Trauma ◽

Subdural Hematoma ◽

Cerebral Hemorrhage ◽

Imaging Modality ◽

Common Type ◽

Radiology Department ◽

Age Group ◽

Ct Finding

Computed Tomography (CT) is the most commonly used imaging modality in the evaluation of cerebral hemorrhage in the head trauma patients. Objective: To study the incidence of a cerebral hemorrhage in traumatic patients using computed tomography. Method: This retrospective study was conducted at King Khalid hospital in Tabuk city, Saudi Arabia, in the radiology department, in the period from September 2018 to April 2020. The study was done by collecting 471 CT reports of patients all of them were exposed to head trauma with deferent reasons. The data were analyzed by Statistical Package for the Social Sciences (SPSS) program (ver. 20) and presented in tables and graphs according to the checklist which includes: patient age, gender, type of trauma, CT finding, and type of hemorrhage. Results: The most age group suffered from head trauma was less than 20 years percentage (55%), The male patients more exposed to head trauma than female patients with percentage (84.5%), the road traffic accident (RTA) is the most common type of trauma by percentage (63.5%), according to the CT finding; the cerebral hemorrhage represented (15.5%) with the highest percentage in a subdural hematoma (31.2%), the fracture represented (2.8%) while the normal appearance represented (81.7%) as the highest percentage. Conclusion: Most of the traumatic brain injury in patients caused cerebral hemorrhage and the CT scan reports show that: the common type of cerebral hemorrhage is subdural hematoma and it is common in males which exposed to (RTA) in the age group (21 - 40) years old.

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