scholarly journals Asthma treatment outcome in adults is associated with rs9910408 in TBX21 gene

2013 ◽  
Vol 3 (1) ◽  
Author(s):  
Anton Lopert ◽  
Matija Rijavec ◽  
Mateja Žavbi ◽  
Peter Korošec ◽  
Matjaž Fležar
2012 ◽  
Vol 16 (3) ◽  
pp. 173-180 ◽  
Author(s):  
Mateja Balantic ◽  
Matija Rijavec ◽  
Maja Skerbinjek Kavalar ◽  
Stanislav Suskovic ◽  
Mira Silar ◽  
...  

2012 ◽  
Vol 49 (3) ◽  
pp. 230-236 ◽  
Author(s):  
Thomas Janssens ◽  
Geert Verleden ◽  
Steven De Peuter ◽  
Sibille Petersen ◽  
Omer van den Bergh

2011 ◽  
Vol 8 (5) ◽  
pp. 16-20
Author(s):  
V K Yakovleva ◽  
Gleb Borisovich Fedoseev ◽  
M V Eliseeva ◽  
V I Trofimov ◽  
V K Yakovleva ◽  
...  

Background. The results of observation of patients with bronchial asthma (ВА), parasitic invasion and intestine disbacteriosis before and after treatment have been described in the article. Methods. The basic group (ВА(+)) included 46 patients with ВА, parasitic invasion, disbacteriosis of intestine or their combination. The control group included 18 patients without disbacteriosis and parasitic invasion. The following examination was done: PS was assessed by ACTtest (asthma Control Test), respiratory function (RF ), helminthoovoscopy of faeces, P CR of faeces for lamblia Giardia, bacteriologic examination of faeces. Results. Complex treatment resulted in improvement of B A symptoms, decreased number of B A relapses and decreased number of hospitalization. Also the increasing of F EF 25 and F EF 50 was evaluated. S ame tendency was not traced in B A group and in patients with isolated lambliosis. Conclusion. Treatment of helminthiasis and intestine disbacteriosis improves the overall bronchial asthma treatment outcome.


2018 ◽  
Vol 5 (1) ◽  
pp. 13-19
Author(s):  
Raja Ahsan Aftab ◽  
Amer Hayat Khan ◽  
Syed Azhar Syed Sulaiman ◽  
Irfhan Ali

Aims and objective: The aim of the current study is to evaluate adherence clinical practice guideline of asthma, to assess treatment outcomes of guideline adhering to pharmacotherapy and to calculate the cost of asthma treatment. Methods: A prospective record viewing study was conducted at the respiratory clinic of Hospital Pulau Pinang, Penang, Malaysia from December 2012 to June 2013. A total of 180 prescriptions of patients from 6 doctors (30 prescriptions by each doctor) were evaluated against global initiative of asthma (GINA) guidelines. Treatment outcomes of asthma patients were evaluated based on lung function values. Direct assessment of cost was compared between the guidelines adhered and non-adhered scripts. Results: Of the total 180 asthmatic patients, 143 (78.9%) received guideline-adhered pharmacotherapy. A total of 158 (87.7%) patients reported successful treatment outcome, out of which, 124 (78.4%) patients received guideline-adhered pharmacotherapy. A statistical significant difference (p < 0.001) was observed among lung function values after patients’ first and second visit. An analysis indicated that patients aged > 46 years were found to have a significant association with treatment outcomes (OR=3.77, p=0.03). While comparing the cost of asthma treatment outcome, it was observed that the average cost of successfully treated patients who received guideline-adhered pharmacotherapy was RM 70.00 per patient (1US$ = RM 3.20) while patients reporting unsuccessful treatment outcome was RM 75.47 per patient. Conclusion: A majority of asthma patients received guideline-adhered pharmacotherapy.


Ob Gyn News ◽  
2005 ◽  
Vol 40 (4) ◽  
pp. 10
Author(s):  
GIDEON KOREN

Author(s):  
Charlotte Jaite ◽  
Betteke Maria van Noort ◽  
Timo D. Vloet ◽  
Erika Graf ◽  
Viola Kappel ◽  
...  

Abstract. Objective: We examined predictors and moderators of treatment outcome in mothers and children diagnosed with ADHD in a large multicentre RCT. Method: In total, 144 mother-child dyads with ADHD were randomly assigned to either a maternal ADHD treatment (group psychotherapy and open methylphenidate medication, TG) or to a control treatment (individual counselling without psycho- or pharmacotherapy, CG). After maternal ADHD treatment, parent-child training (PCT) for all mother-child dyads was added. The final analysis set was based on 123 dyads with completed primary outcome assessments (TG: n = 67, CG: n = 56). The primary outcome was the change in each child’s externalizing symptoms. Multiple linear regression analyses were performed. Results: The severity of the child’s externalizing problem behaviour in the family at baseline predicted more externalizing symptoms in the child after PCT, independent of maternal treatment. When mothers had a comorbid depression, TG children showed more externalizing symptoms after PCT than CG children of depressive mothers. No differences between the treatment arms were seen in the mothers without comorbid depression. Conclusions: Severely impaired mothers with ADHD and depressive disorder are likely to need additional disorder-specific treatment for their comorbid psychiatric disorders to effectively transfer the contents of the PCT to the home situation (CCTISRCTN73911400).


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