A new series of 5-(5-aryl-1-phenyl-1H-pyrazol-3-yl)-3-aryl-1,2,4-oxadiazole (6a-o) have been
synthesized by a cyclocondensation reaction of ethyl 5-(4-chlorophenyl)-1-phenyl-1H-pyrazole-3-
carboxylate (3a-c) with aryl imidoxime (5a-e). The newly synthesized pyrazolyl-1,2,4-oxadiazole
(6a-o) derivatives were characterized by spectroscopic techniques and screened for in vitro antibacterial
activity against Bacillus subtilis (NCIM 2063), Staphylococcus albus (NCIM 2178), Escherichia coli
(NCIM 2574), Proteus mirabilis (NCIM 2388) and in vitro antifungal activity against Aspergillus
niger (ATCC 504) Candida albicans (NCIM 3100).