Amplified inhibition of the electrochemical signal of graphene–thionine nanocomposites using silica nanoprobes for ultrasensitive electrochemical immunoassays

2014 ◽  
Vol 6 (7) ◽  
pp. 2080-2085 ◽  
Author(s):  
Guosong Lai ◽  
Cuiying Yin ◽  
Xiangen Tan ◽  
Haili Zhang ◽  
Aimin Yu
Keyword(s):  
Electrochemical Signal ◽  
Electrochemical Immunoassays

The amplified inhibition of the electrochemical signal of graphene–thionine nanocomposites using silica nanoprobes enabled a novel ultrasensitive immunoassay method.

scholarly journals Selective Enhancement of Electrochemical Signal Based on the Size of Alcohols Using Nanoporous Platinum

2021 ◽  
Author(s):  
Jae Jin Bang ◽  
Donghoon Han ◽  
Jinsik Shin ◽  
Taek Dong Chung ◽  
Je Hyun Bae
Keyword(s):  
Electrochemical Signal ◽  
Selective Enhancement ◽  
Nanoporous Platinum

scholarly journals Metal Nanoparticle and Quantum Dot Tags for Signal Amplification in Electrochemical Immunosensors for Biomarker Detection

Chemosensors ◽  
2021 ◽  
Vol 9 (4) ◽  
pp. 85
Author(s):  
Anton Popov ◽  
Benediktas Brasiunas ◽  
Asta Kausaite-Minkstimiene ◽  
Almira Ramanaviciene
Keyword(s):  
Signal Amplification ◽  
Electrochemical Immunosensor ◽  
Metal Nanoparticle ◽  
Biomarker Detection ◽  
Analytical Instruments ◽  
Electrochemical Immunosensors ◽  
Highly Sensitive ◽  
Recent Developments ◽  
Electrochemical Signal ◽  
Detection Of Biomarkers

With the increasing importance of healthcare and clinical diagnosis, as well as the growing demand for highly sensitive analytical instruments, immunosensors have received considerable attention. In this review, electrochemical immunosensor signal amplification strategies using metal nanoparticles (MNPs) and quantum dots (Qdots) as tags are overviewed, focusing on recent developments in the ultrasensitive detection of biomarkers. MNPs and Qdots can be used separately or in combination with other nanostructures, while performing the function of nanocarriers, electroactive labels, or catalysts. Thus, different functions of MNPs and Qdots as well as recent advances in electrochemical signal amplification are discussed. Additionally, the methods most often used for antibody immobilization on nanoparticles, immunoassay formats, and electrochemical methods for indirect biomarker detection are overviewed.

Enzyme-induced Cu2+/Cu+ conversion as the electrochemical signal for sensitive detection of ethyl carbamate

2021 ◽  
Vol 1151 ◽  
pp. 338256
Author(s):  
Long Wu ◽  
Yasheng Wang ◽  
Shuhong Zhou ◽  
Yongheng Zhu ◽  
Xiaoqiang Chen
Keyword(s):  
Ethyl Carbamate ◽  
Sensitive Detection ◽  
Electrochemical Signal

Sensitivity Improvement in Electrochemical Immunoassays Using Antibody Immobilized Magnetic Nanoparticles with a Clean ITO Working Electrode

2020 ◽  
Vol 14 (3) ◽  
pp. 308-316
Author(s):  
Sunga Song ◽  
Young Joo Kim ◽  
Hye-Lim Kang ◽  
Sumi Yoon ◽  
Dong-Ki Hong ◽  
...  
Keyword(s):  
Magnetic Nanoparticles ◽  
Working Electrode ◽  
Sensitivity Improvement ◽  
Electrochemical Immunoassays

Enhancement of Electrochemical Signal on Gold Electrodes by Polyvalent Esterase−Dendrimer Clusters

2008 ◽  
Vol 19 (12) ◽  
pp. 2456-2461 ◽  
Author(s):  
Martin Humenik ◽  
Christopher Pöhlmann ◽  
Yiran Wang ◽  
Mathias Sprinzl
Keyword(s):  
Gold Electrodes ◽  
Electrochemical Signal

scholarly journals DNA/RNA Electrochemical Biosensing Devices a Future Replacement of PCR Methods for a Fast Epidemic Containment

Sensors ◽  
2020 ◽  
Vol 20 (16) ◽  
pp. 4648 ◽  
Author(s):  
Manikandan Santhanam ◽  
Itay Algov ◽  
Lital Alfonta
Keyword(s):  
Signal Amplification ◽  
Nucleic Acid Hybridization ◽  
Diagnostic Tools ◽  
Testing Method ◽  
Reverse Transcription Pcr ◽  
Electrochemical Biosensing ◽  
Low Copy Number ◽  
Rna Sensors ◽  
Electrochemical Signal ◽  
Sensitive Testing

Pandemics require a fast and immediate response to contain potential infectious carriers. In the recent 2020 Covid-19 worldwide pandemic, authorities all around the world have failed to identify potential carriers and contain it on time. Hence, a rapid and very sensitive testing method is required. Current diagnostic tools, reverse transcription PCR (RT-PCR) and real-time PCR (qPCR), have its pitfalls for quick pandemic containment such as the requirement for specialized professionals and instrumentation. Versatile electrochemical DNA/RNA sensors are a promising technological alternative for PCR based diagnosis. In an electrochemical DNA sensor, a nucleic acid hybridization event is converted into a quantifiable electrochemical signal. A critical challenge of electrochemical DNA sensors is sensitive detection of a low copy number of DNA/RNA in samples such as is the case for early onset of a disease. Signal amplification approaches are an important tool to overcome this sensitivity issue. In this review, the authors discuss the most recent signal amplification strategies employed in the electrochemical DNA/RNA diagnosis of pathogens.

scholarly journals Tungsten disulfide nanosheets supported poly(xanthurenic acid) as a signal transduction interface for electrochemical genosensing applications

RSC Advances ◽  
2018 ◽  
Vol 8 (69) ◽  
pp. 39703-39709 ◽  
Author(s):  
Jimin Yang ◽  
Xuesong Yin ◽  
Min Xia ◽  
Wei Zhang
Keyword(s):  
Signal Transduction ◽  
Tungsten Disulfide ◽  
Xanthurenic Acid ◽  
Pik3ca Gene ◽  
Electrochemical Signal

An electrochemical signal transduction sensing interface for detecting PIK3CA gene was developed based on WS2 nanosheets supported PXa.

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