Novel fluorescent sensors based on benzimidazo[2,1-a]benz[de]isoquinoline-7-one-12-carboxylic acid for Cu2+

RSC Advances ◽  
2014 ◽  
Vol 4 (100) ◽  
pp. 56863-56869 ◽  
Author(s):  
Zheng Liu ◽  
Yuhua Qi ◽  
Chaoxia Guo ◽  
Yingying Zhao ◽  
Xiaofeng Yang ◽  
...  

(1) Two new fluorescent sensors were developed based on benzimidazo[2,1-a]benz[de]isoquinoline-7-one. (2) BothC1andC2showed fluorescence turn-on response toward Cu2+in buffer solutions. (3) The detection limit of C1 towards Cu2+reached 5.7 × 10−8M. (4) The Cu2+sensing ofC1andC2were both based on the PET process. (5) Addition of OH−could lead to significantly color changes ofC1solution.

Molecules ◽  
2019 ◽  
Vol 24 (17) ◽  
pp. 3102 ◽  
Author(s):  
Bin Li ◽  
Datong Zhang ◽  
Ruibing An ◽  
Yaling Zhu

In this work, a novel 7-hydroxybenzoxazinone-based fluorescent probe (PBD) for the selective sensing of biothiols is reported. Upon treatment with biothiols, PBD shows a strong fluorescence enhancement (up to 70-fold) and a large Stokes shift (155 nm). Meanwhile, this probe exhibits high resistance to interference from other amino acids and competing species. PBD features good linearity ranges with a low detection limit of 14.5 nM for glutathione (GSH), 17.5 nM for cysteine (Cys), and 80.0 nM for homocysteine (Hcy), respectively. Finally, the potential utility of this probe for biothiol sensing in living HeLa cells is demonstrated.


2020 ◽  
Vol 44 (28) ◽  
pp. 12019-12026 ◽  
Author(s):  
Divya Singhal ◽  
Ismail Althagafi ◽  
Ashish Kumar ◽  
Saroj Yadav ◽  
Ashok K. Prasad ◽  
...  

Thieno[3,2-c]pyran was synthesized as a fluorescent turn-on chemosensor for the selective recognition of Zn2+ ions with a low detection limit (0.67 μM), and it also exhibited AIE properties.


RSC Advances ◽  
2016 ◽  
Vol 6 (57) ◽  
pp. 52004-52008 ◽  
Author(s):  
Xiaofeng Yang ◽  
Yan Zhang ◽  
Yexin Li ◽  
Xiaolei Liu ◽  
Jiaxin Mao ◽  
...  

A diketopyrrolopyrrole-based fluorescent probeDPP-HBTbearing a benzothiazole hydrazone motif exhibited an obvious fluorescent turn-on response toward Pb2+ions with a low detection limit of 2.3 × 10−10M in aqueous solution.


2018 ◽  
Vol 16 (1) ◽  
pp. 1268-1274 ◽  
Author(s):  
Jiaoliang Wang ◽  
Liping Long ◽  
Guing Xiao ◽  
Fang Fang

AbstractCompounds Rh6G-1 and RhB-2 with a novel receptor composed of tri-oxygen atoms of amide groups were designed and synthesized as new reversible fluorescent sensors for Fe3+. The prominent features of the novel sensor Rh6G-1 include a large fluorescence turn-on response in essentially pure water at room temperature, high sensitivity, high selectivity, a limit of detection, cell membrane permeability, and low cytotoxicity. These desirable attributes enable us to successfully employ the new sensor Rh6G-1 for Fe3+ bioimaging in living cells.


Molecules ◽  
2021 ◽  
Vol 26 (11) ◽  
pp. 3180
Author(s):  
Yina Cai ◽  
Binxue Ren ◽  
Chifang Peng ◽  
Cunzheng Zhang ◽  
Xinlin Wei

New nanocomposites, Fe3O4@Au–FITC, were prepared and explored to develop a fluorescent detection of Pb2+. The Fe3O4@AuNPs–FITC nanocomposites could be etched by Pb2+ in the presence of Na2S2O3, leading to fluorescence recovery of FITC quenched by Fe3O4@Au nanocomposites. With the increase of Pb2+ concentration, the fluorescence recovery of Fe3O4@AuNPs–FITC increased gradually. Under optimized conditions, a detection limit of 5.2 nmol/L of Pb2+ with a linear range of 0.02–2.0 µmol/L were obtained. The assay demonstrated negligible response to common metal ions. Recoveries of 98.2–106.4% were obtained when this fluorescent method was applied in detecting Pb2+ spiked in a lake-water sample. The above results demonstrated the high potential of ion-induced nanomaterial etching in developing robust fluorescent assays.


2009 ◽  
Vol 38 (9) ◽  
pp. 2543 ◽  
Author(s):  
Meaghan E. Germain ◽  
Michael J. Knapp

RSC Advances ◽  
2017 ◽  
Vol 7 (47) ◽  
pp. 29697-29701 ◽  
Author(s):  
Jing-Han Hu ◽  
Jian-Bin Li ◽  
You Sun ◽  
Peng-Xiang Pei ◽  
Jing Qi

A novel highly selective chemosensor for Mg2+ ions based on the naphthalene group as the fluorophore has been designed and synthesized, which shows a fluorescence turn-on response from colorless to green for Mg2+ ions in DMSO–H2O solutions.


2014 ◽  
Vol 6 (8) ◽  
pp. 2499-2505 ◽  
Author(s):  
Wenzhu Zhang ◽  
Ping Zhang ◽  
Shengzhou Zhang ◽  
Changqing Zhu

A quantum-dot-based fluorescence turn-on sensor was used for label-free and real-time monitoring of trypsin activity.


2018 ◽  
Author(s):  
Suying Xu ◽  
Adam Sedgwick ◽  
Souad Elfecky ◽  
Wenbo Chen ◽  
Ashley Jones ◽  
...  

<p>A boronic acid-based anthracene fluorescent probe was functionalised with an acrylamide unit to incorporate into a hydrogel system for monosaccharide detection<i>. </i>In solution, the fluorescent probe<b> </b>displayed a strong fluorescence turn-on response upon exposure to fructose, and an expected trend in apparent binding constants, as judged by a fluorescence response where D-fructose > D-galactose > D-mannose > D-glucose. The hydrogel incorporating the boronic acid monomer demonstrated the ability to detect monosaccharides by fluorescence with the same overall trend as the monomer in solution with the addition of fructose resulting in a 10-fold enhancement (≤ 0.25 M). <b><u></u></b></p>


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