Portable and quantitative monitoring of mercury ions using DNA-gated mesoporous silica nanoparticles using a glucometer readout

2016 ◽  
Vol 52 (10) ◽  
pp. 2192-2194 ◽  
Author(s):  
Xiaoling Liang ◽  
Lin Wang ◽  
Dou Wang ◽  
Lingwen Zeng ◽  
Zhiyuan Fang

A novel glucometer biosensor was developed for the quantitative detection of mercury ions (Hg2+) based on glucose-loaded DNA-gated mesoporous silica nanoparticles (MSNs).

2014 ◽  
Vol 2 (35) ◽  
pp. 5847-5853 ◽  
Author(s):  
Youmei Wang ◽  
Minghua Lu ◽  
Jinhua Zhu ◽  
Shufang Tian

This work reports a simple and sensitive sensing protocol for the quantitative monitoring of telomerase activity based on target-responsive release of cargo from wrapping DNA-capped mesoporous silica nanoparticles (MSNs) by coupling with a portable personal glucometer (PGM).


2021 ◽  
Author(s):  
Morvarid Aghayan ◽  
Ali Mahmoudi ◽  
Mohammad Reza Sazegar ◽  
Forogh Adhami

In an attempt to explore the significance of inorganic mimetic enzymes as sensors, this study introduces a naked-eye analytical sensing platform for the detection of L-cysteine (cys), mercury ions (Hg2+)...


2020 ◽  
Vol 20 (11) ◽  
pp. 1001-1016
Author(s):  
Sandra Ramírez-Rave ◽  
María Josefa Bernad-Bernad ◽  
Jesús Gracia-Mora ◽  
Anatoly K. Yatsimirsky

Hybrid materials based on Mesoporous Silica Nanoparticles (MSN) have attracted plentiful attention due to the versatility of their chemistry, and the field of Drug Delivery Systems (DDS) is not an exception. MSN present desirable biocompatibility, high surface area values, and a well-studied surface reactivity for tailoring a vast diversity of chemical moieties. Particularly important for DDS applications is the use of external stimuli for drug release. In this context, light is an exceptional alternative due to its high degree of spatiotemporal precision and non-invasive character, and a large number of promising DDS based on photoswitchable properties of azobenzenes have been recently reported. This review covers the recent advances in design of DDS using light as an external stimulus mostly based on literature published within last years with an emphasis on usually overlooked underlying chemistry, photophysical properties, and supramolecular complexation of azobenzenes.


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