The Controlled Release of Drugs and Bioactive Compounds from Mesoporous Silica Nanoparticles

2016 ◽  
Vol 13 (6) ◽  
pp. 839-856 ◽  
Author(s):  
Mohammad A. Chowdhury
2015 ◽  
Vol 26 (10) ◽  
pp. 1203-1208 ◽  
Author(s):  
Yu-Jie Chang ◽  
Xi-Zhen Liu ◽  
Qing Zhao ◽  
Xiao-Hai Yang ◽  
Ke-Min Wang ◽  
...  

2018 ◽  
Vol 340 ◽  
pp. 2-8 ◽  
Author(s):  
Juan L. Paris ◽  
Christophoros Mannaris ◽  
M. Victoria Cabañas ◽  
Robert Carlisle ◽  
Miguel Manzano ◽  
...  

2016 ◽  
Vol 22 (39) ◽  
pp. 13935-13945 ◽  
Author(s):  
Sameh El Sayed ◽  
Michele Milani ◽  
Chiara Milanese ◽  
Maurizio Licchelli ◽  
Ramón Martínez-Máñez ◽  
...  

2014 ◽  
Vol 2 (47) ◽  
pp. 8298-8302 ◽  
Author(s):  
Prasanna Lakshmi Abbaraju ◽  
Anand kumar Meka ◽  
Siddharth Jambhrunkar ◽  
Jun Zhang ◽  
Chun Xu ◽  
...  

Floating tablets were prepared using hydrophobic (curcumin) and hydrophilic (captopril) drug loaded mesoporous silica nanoparticles respectively, leading to an improved dissolution rate of curcumin and controlled release for captopril.


Pharmaceutics ◽  
2020 ◽  
Vol 12 (5) ◽  
pp. 432 ◽  
Author(s):  
Rafael R. Castillo ◽  
Daniel Lozano ◽  
María Vallet-Regí

The enormous versatility of mesoporous silica nanoparticles permits the creation of a large number of nanotherapeutic systems for the treatment of cancer and many other pathologies. In addition to the controlled release of small drugs, these materials allow a broad number of molecules of a very different nature and sizes. In this review, we focus on biogenic species with therapeutic abilities (proteins, peptides, nucleic acids, and glycans), as well as how nanotechnology, in particular silica-based materials, can help in establishing new and more efficient routes for their administration. Indeed, since the applicability of those combinations of mesoporous silica with bio(macro)molecules goes beyond cancer treatment, we address a classification based on the type of therapeutic action. Likewise, as illustrative content, we highlight the most typical issues and problems found in the preparation of those hybrid nanotherapeutic materials.


2020 ◽  
Vol 8 ◽  
Author(s):  
Alessandro Presentato ◽  
Francesco Armetta ◽  
Alberto Spinella ◽  
Delia Francesca Chillura Martino ◽  
Rosa Alduina ◽  
...  

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