An inner filter effect based sensor of tetracycline hydrochloride as developed by loading photoluminescent carbon nanodots in the electrospun nanofibers

Nanoscale ◽  
2016 ◽  
Vol 8 (5) ◽  
pp. 2999-3007 ◽  
Author(s):  
Min Lin ◽  
Hong Yan Zou ◽  
Tong Yang ◽  
Ze Xi Liu ◽  
Hui Liu ◽  
...  

Highly photoluminescent carbon nanodots (CDs), which have been loaded in the electrospun nanofibers, are applied to develop an IFE-based visual sensor for tetracycline hydrochloride (Tc) sensing in milk.

2019 ◽  
Vol 280 ◽  
pp. 195-202 ◽  
Author(s):  
Qin Hu ◽  
Lu Gao ◽  
Sheng-qi Rao ◽  
Zhen-quan Yang ◽  
Tao Li ◽  
...  

Materials ◽  
2020 ◽  
Vol 13 (10) ◽  
pp. 2275 ◽  
Author(s):  
Baraa Al-Hashimi ◽  
Heshu Sulaiman Rahman ◽  
Khalid Mohammad Omer

The determination of rifampicin in pharmaceutical dosage forms using a rapid, sensitive, selective, biocompatible, and low-cost method is of vital importance in the pharmaceutical analysis field to ensure its concentration is within the effective range when administered. In this study, nitrogen-and-phosphorous-doped carbon nanodots (CNDs) were prepared using a single-step hydrothermal method with ciprofloxacin as the starting material. The CNDs showed a highly intense blue fluorescence emission centered at 450 nm, with a photoluminescence quantum yield of about 51%. Since the absorption of rifampicin was the same as the excitation spectrum of CNDs, inner filter effect (IFE) quenching occurred and it was used as a successful detection platform for the analysis of rifampicin in capsules. The detection platform showed a dynamic linear range from 1 to 100 μM (R2 = 0.9940) and the limit of detection was 0.06 μM (when S/N = 3). The average spike recovery percentage for rifampicin in the capsule samples was 100.53% (n = 5). Moreover, the sub-chronic cytotoxicity of CNDs was evaluated on healthy male mice (Balb/c) drenched with different amounts of CNDs (10 and 50 mg/kg). During this study period, no mortalities or toxicity signs were recorded in any of the experimental subjects. Based on the cytotoxicity experiment, the proposed nano-probe is considered safe and biocompatible.


Author(s):  
Liman Sai ◽  
Xingyang Wang ◽  
Quanhong Chang ◽  
Wangzhou Shi ◽  
Lei Huang

2021 ◽  
Vol 112 ◽  
pp. 110743
Author(s):  
Min Yang ◽  
Yujia Yan ◽  
Enzhou Liu ◽  
Xiaoyun Hu ◽  
Hong Hao ◽  
...  

2021 ◽  
Author(s):  
Qianqian Zhao ◽  
Datong Wu ◽  
Zhengzhi Yin ◽  
Wenrong Cai ◽  
Haifeng Zhou ◽  
...  

A fluorescent chiral sensor is proposed based on the inner filter effect (IFE) of chiral Au nanoparticles (AuNPs) on MoS2 quantum dots (MoS2 QDs), which can be used for the...


RSC Advances ◽  
2021 ◽  
Vol 11 (34) ◽  
pp. 21137-21144
Author(s):  
Mengyuan He ◽  
Ning Shang ◽  
Bo Zheng ◽  
Gege Yue

An ultrasensitive colorimetric and fluorescence dual-readout assay based on carbon dot–MnO2 nanosheets platform was developed for GSH detection in human body fluid samples.


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