Reducing the cytotoxicity while improving the anti-cancer activity of silver nanoparticles through α-tocopherol succinate modification

RSC Advances ◽  
2015 ◽  
Vol 5 (100) ◽  
pp. 82050-82055 ◽  
Author(s):  
Guansong Hu ◽  
Yuchun Cai ◽  
Zhengchao Tu ◽  
Jinfeng Luo ◽  
Xueliang Qiao ◽  
...  
Keyword(s):  
Silver Nanoparticles ◽  
Ag Nps ◽  
Anti Cancer ◽  
Cancer Activity

α-TOS modified Ag NPs could reduce the cytotoxicity while improving the anti-cancer activity of Ag NPs.

scholarly journals Photocatalytic degradation and anti-cancer activity of biologically synthesized Ag NPs for inhibit the MCF-7 breast cancer cells

2021 ◽  
pp. 101725
Author(s):  
Govindan Nadar Rajivgandhi ◽  
Govindan Ramachandran ◽  
Moorthy Rajesh Kannan ◽  
Arockiam Antony Joseph Velanganni ◽  
Muhammad Zubair Siddiqi ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Photocatalytic Degradation ◽  
Cancer Cells ◽  
Breast Cancer Cells ◽  
Ag Nps ◽  
Anti Cancer ◽  
Cancer Activity ◽  
Mcf 7

scholarly journals Anti-cancer activity of biosynthesized silver nanoparticles using Avicennia marina against A549 lung cancer cells through ROS/mitochondrial damages

2020 ◽  
Vol 27 (11) ◽  
pp. 3018-3024 ◽  
Author(s):  
Shan Tian ◽  
Kandasamy Saravanan ◽  
Ramzi A. Mothana ◽  
Govindan Ramachandran ◽  
Govindan Rajivgandhi ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Silver Nanoparticles ◽  
Cancer Cells ◽  
Avicennia Marina ◽  
Lung Cancer Cells ◽  
Anti Cancer ◽  
A549 Lung ◽  
Cancer Activity

Anti-cancer activity of camptothecin nanocrystals decorated by silver nanoparticles

2017 ◽  
Vol 5 (14) ◽  
pp. 2692-2701 ◽  
Author(s):  
Honglei Zhan ◽  
Xiaqing Zhou ◽  
Yang Cao ◽  
Tina Jagtiani ◽  
Tzu-Lan Chang ◽  
...  
Keyword(s):  
Silver Nanoparticles ◽  
Broad Spectrum ◽  
High Selectivity ◽  
Anti Cancer ◽  
Cancer Activity

CPT/Ag nanocrystals display extreme and broad-spectrum anti-cancer activity and high selectivity through a cooperation effect between CPT and AgNPs.

scholarly journals Silver Nanoparticles: Cytotoxic and Apoptotic Activity on HT-29 and A549 Cell Lines

2018 ◽  
Vol 1 (4) ◽  
pp. 1-6 ◽  
Author(s):  
Abdolhossien Miri ◽  
Mina Sarani
Keyword(s):  
Silver Nanoparticles ◽  
Cell Lines ◽  
A549 Cell ◽  
A549 Cell Line ◽  
Tunel Method ◽  
Ag Nps ◽  
Anti Cancer ◽  
Cancer Agent ◽  
Apoptotic Activity ◽  
Ht 29

Silver nanoparticles (Ag-NPs) are versatile materials with a broad range of applications in various fields such as cancer therapy, drug delivery. In this work, cytotoxic and apoptotic activities of silver nanoparticles was evaluation against lung (A549) and colon (HT-29) cell lines. The cytotoxic activity of nanoparticles was performed by MTT assay, while their apoptotic activity was tested through TUNEL method. The results of MTT of A549 have illustrate that fifty percent of cells destruction in concentrations more than 250 µg/ml of Ag-NPs. Apoptotic results of nanoparticles have shown more than fifty percent of apoptosis on A549 cell line. HT-29 display full apoptosis at concentrations more than 500 µg/ml. It seems that synthesized Ag-NPs by using P. farcta extract can be candidate as anti-cancer agent in treatment many cancers through creating or discovering new drug forms

scholarly journals Pollen Bee Aqueous Extract-Based Synthesis of Silver Nanoparticles and Evaluation of Their Anti-Cancer and Anti-Bacterial Activities

Processes ◽  
2020 ◽  
Vol 8 (5) ◽  
pp. 524
Author(s):  
Hanan M. Al-Yousef ◽  
Musarat Amina ◽  
Ali S. Alqahtani ◽  
Mohammed S. Alqahtani ◽  
Abdul Malik ◽  
...  
Keyword(s):  
Silver Nanoparticles ◽  
Cell Lines ◽  
Aqueous Extract ◽  
Antibacterial Properties ◽  
Essential Amino Acids ◽  
Spectroscopic Techniques ◽  
Human Beings ◽  
Ag Nps ◽  
Anti Cancer ◽  
Ic50 Values

Bee pollens are rich source of essential amino acids and are often considered as complete food for human beings. Herein, we exploited the potential reducing abilities of Bee pollens extract for the eco-friendly preparation of silver nanoparticles (AgNPs-G). The resulting NPs were characterized using a combination of microscopic and spectroscopic techniques. The analyses confirm the formation of spherical Ag NPs. AgNPs-G obtained from the aqueous extract of bee pollens was used to study their antibacterial properties against Gram-positive and Gram-negative microbes using the Minimum Inhibitory Concentration 50 (MIC50) method. The antibacterial properties of AgNPs-G were compared to the properties of chemically synthesized Ag NPs (AgNPs-C) using sodium borohydride as a reducing agent. The green synthesized nanoparticles (AgNPs-G) exhibited a better antibacterial activity against most of the studied strains when compared to the chemically synthesized Ag NPs (AgNPs-C). In addition, the anti-cancer activity of Ag NPs was also studied against human liver and breast carcinoma cell lines by applying MTT-assay. The Ag NPs demonstrated considerable anticancer activity against the studied cell lines and exhibited high IC50 values in both MCF-7 and HepG2 cell lines.

Modulating chromatin structure and DNA accessibility by deacetylase inhibition enhances the anti-cancer activity of silver nanoparticles

2016 ◽  
Vol 146 ◽  
pp. 670-677 ◽  
Author(s):  
Nóra Igaz ◽  
Dávid Kovács ◽  
Zsolt Rázga ◽  
Zoltán Kónya ◽  
Imre M. Boros ◽  
...  
Keyword(s):  
Silver Nanoparticles ◽  
Chromatin Structure ◽  
Dna Accessibility ◽  
Anti Cancer ◽  
Cancer Activity

In-vitro anti-cancer activity of shape controlled silver nanoparticles (AgNPs) in various organ specific cell lines

2017 ◽  
Vol 242 ◽  
pp. 757-766 ◽  
Author(s):  
Sabina Yeasmin ◽  
Hemanta Kumar Datta ◽  
Sujata Chaudhuri ◽  
Debasish Malik ◽  
Abhijit Bandyopadhyay
Keyword(s):  
Silver Nanoparticles ◽  
Cell Lines ◽  
Specific Cell ◽  
Anti Cancer ◽  
Organ Specific ◽  
Shape Controlled ◽  
Cancer Activity

PEGylated silver nanoparticles from Sesbania aegyptiaca exhibit immunomodulatory and anti-cancer activity

2018 ◽  
Vol 6 (3) ◽  
pp. 035402 ◽  
Author(s):  
Sureshbabu Ram Kumar Pandian ◽  
Dayalan Anjanei ◽  
NR Livingston Raja ◽  
Krishnan Sundar
Keyword(s):  
Silver Nanoparticles ◽  
Anti Cancer ◽  
Cancer Activity
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