Biologizing titanium alloy implant material with morphogenetically active polyphosphate

RSC Advances ◽  
2015 ◽  
Vol 5 (92) ◽  
pp. 75465-75473 ◽  
Author(s):  
Werner E. G. Müller ◽  
Emad Tolba ◽  
Heinz C. Schröder ◽  
Shunfeng Wang ◽  
Gunnar Glasser ◽  
...  

As a further step towards a new generation of bone implant materials, we developed a procedure for biological functionalization of titanium alloy surfaces with inorganic calcium polyphosphate (Ca-polyP).

2010 ◽  
Vol 6 (8) ◽  
pp. 3318-3324 ◽  
Author(s):  
Christian Symietz ◽  
Erhard Lehmann ◽  
Renate Gildenhaar ◽  
Jörg Krüger ◽  
Georg Berger

RSC Advances ◽  
2019 ◽  
Vol 9 (18) ◽  
pp. 10081-10090 ◽  
Author(s):  
Dengyu Liu ◽  
Zhenghou Zhu ◽  
Jia Zhou ◽  
Hui Zhao ◽  
Jie Chen ◽  
...  

Hydroxyapatite (HAP)/polyetheretherketone (PEEK) composites are widely used in the new generation of bone implant materials.


2020 ◽  
Vol 1000 ◽  
pp. 97-106
Author(s):  
Dian Juliadmi ◽  
Nuzul Ficky Nuswantoro ◽  
Hidayatul Fajri ◽  
Irma Yulia Indriyani ◽  
Jon Affi ◽  
...  

Research about the utilization of titanium alloy (Ti-6Al-4V ELI) as implant material in the treatment of orthopedic cases had been increasing. Health problems appear due to the drawbacks of using titanium. The lack of titanium using is bio-inertness characteristic, which decreasing its bioactivity and results in low bone growth and effect for implant failure. The titanium can be modified with coating on the surface using a bioactive substance that is natural-source hydroxyapatite. Bovine-source hydroxyapatite (bovineHA) contains apatite component that is similar to human bone apatite. The coating process was carried out using particle size variation (25 μm, 63 μm, and 125 μm) of bovineHA. The electrophoretic deposition (EPD) method was applied to coat hydroxyapatite with 10 volt for 5 minutes onto the titanium surface. The result showed that different size particles have an effect on coating properties. The coating composed by particle-sized 25 μm has better surface coverage (95.89%), indicating more particle mass (particle weight 6.97x103 μg) attached to surface material, thus resulting thick coating. The good coating characteristic using bovine-source hydroxyapatite with small particle size was expected can be used in biomedical applications due to fulfill the prerequisite of the bone implant.


Author(s):  
Yusuf Kaynak ◽  
Armin Gharibi

Titanium alloy Ti-5Al-5V-3Cr-0.5Fe (Ti-5553) is a new generation of near-beta titanium alloy that is commonly used in the aerospace industry. Machining is one of the manufacturing methods to produce parts that are made of this near-beta alloy. This study presents the machining performance of new generation near-beta alloys, namely, Ti-5553, by focusing on a high-speed cutting process under cryogenic cooling conditions and dry machining. The machining experiments were conducted under a wide range of cutting speeds, including high speeds that used liquid nitrogen (LN2) and carbon dioxide (CO2) as cryogenic coolants. The experimental data on the cutting temperature, tool wear, force components, chip breakability, dimensional accuracy, and surface integrity characteristics are presented and were analyzed to evaluate the machining process of this alloy and resulting surface characteristics. This study shows that cryogenic machining improved the machining performance of the Ti-5553 alloy by substantially reducing the tool wear, cutting temperature, and dimensional deviation of the machined parts. The cryogenic machining also produced shorter chips as compared to dry machining.


Author(s):  
Vinod Kumar ◽  
Bipul Tripathi ◽  
Anchal Srivastava ◽  
Preeti S. Saxena

2019 ◽  
Vol 5 (7) ◽  
pp. 3260-3269 ◽  
Author(s):  
Victor Prévost ◽  
Karine Anselme ◽  
Olivier Gallet ◽  
Mathilde Hindié ◽  
Tatiana Petithory ◽  
...  

2019 ◽  
Vol 6 (2) ◽  
pp. 51 ◽  
Author(s):  
Mohammad Elahinia ◽  
Hamdy Ibrahim ◽  
Mohammad Javad Mahtabi ◽  
Reza Mehrabi

This special issue is dedicated to the simulation as well as experimental studies of biomechanical behavior of biomaterials, especially those that are used for bone implant applications [...]


2016 ◽  
Vol 2016 ◽  
pp. 1-6 ◽  
Author(s):  
Kun Mediaswanti

Biofilm formation on implant materials is responsible for periprosthetic infections. Bacterial attachment is important as the first stage in biofilm formation. It is meaningful to understand the influence of nanostructured surface on bacterial attachment. This review discusses the influence of physicochemical aspects of substratum nanosurface on bacterial attachment.


2019 ◽  
Vol 16 (2) ◽  
pp. 359-372
Author(s):  
Ravishanker Baliga ◽  
Sharat K. Rao ◽  
Raghuvir Pai ◽  
Satish B. Shenoy ◽  
Atmananda K. Hegde ◽  
...  

Purpose The purpose of this paper is to investigate by means of finite element analysis (FEA), the effect of polyethylene insert thickness and implant material, under axial loading following TKA. Design/methodology/approach The 3D geometric model of bone was processed using the CT scan data by MIMICS (3matic Inc.), package. Implant components were 3D scanned and subsequently 3D modeled using ANSYS Spaceclaim and meshed in Hypermesh (Altair Hyperworks). The assembled, meshed bone-implant model was then input to ABAQUS for FE simulations, considering axial loading. Findings Polyethylene insert thickness was found to have very little or no significance (p>0.05) on the mechanical performance, namely, stress, strain and stress shielding of bone-implant system. Implant material was found to have a very significant effect (p<0.05) on the performance parameters and greatly reduced the high stress zones up to 60 percent on the tibial flange region and periprosthetic region of tibia. Originality/value Very few FEA studies have been done considering a full bone with heterogeneous material properties, to save computational time. Moreover, four different polyethylene insert thickness with a metal-backed and all-poly tibial tray was considered as the variables affecting the bone-implant system response, under static axial loading. The authors believe that considering a full bone shall lead to more precise outcomes, in terms of the response of bone-implant system, namely, stress, strains and stress shielding in the periprosthetic region, to loading.


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