In situ tuning of gold nanorod plasmon through oxidative cyanide etching

2016 ◽  
Vol 18 (23) ◽  
pp. 15619-15624 ◽  
Author(s):  
Aquiles Carattino ◽  
Saumyakanti Khatua ◽  
Michel Orrit
Keyword(s):  
Gold Nanorods ◽  
Plasmon Resonance ◽  
Photothermal Therapy ◽  
Red Shift ◽  
Gold Nanorod

Single gold nanorods exhibit great opportunities for bio-sensing, enhanced spectroscopies and photothermal therapy. We show how to red-shift the plasmon resonance of single nanorods controllably.

scholarly journals A Novel Fast Photothermal Therapy Using Hot Spots of Gold Nanorods for Malignant Melanoma Cells

Nanomaterials ◽  
2018 ◽  
Vol 8 (11) ◽  
pp. 880 ◽  
Author(s):  
Yanhua Yao ◽  
Nannan Zhang ◽  
Xiao Liu ◽  
Qiaofeng Dai ◽  
Haiying Liu ◽  
...  
Keyword(s):  
Cell Death ◽  
Malignant Melanoma ◽  
Gold Nanorods ◽  
Plasmon Resonance ◽  
Photothermal Therapy ◽  
Treatment Time ◽  
High Energy ◽  
Melanoma Cells ◽  
Photothermal Effect ◽  
A375 Cells

In this paper, the plasmon resonance effects of gold nanorods was used to achieve rapid photothermal therapy for malignant melanoma cells (A375 cells). After incubation with A375 cells for 24 h, gold nanorods were taken up by the cells and gold nanorod clusters were formed naturally in the organelles of A375 cells. After analyzing the angle and space between the nanorods in clusters, a series of numerical simulations were performed and the results show that the plasmon resonance coupling between the gold nanorods can lead to a field enhancement of up to 60 times. Such high energy localization causes the temperature around the nanorods to rise rapidly and induce cell death. In this treatment, a laser as low as 9.3 mW was used to irradiate a single cell for 20 s and the cell died two h later. The cell death time can also be controlled by changing the power of laser which is focused on the cells. The advantage of this therapy is low laser treatment power, short treatment time, and small treatment range. As a result, the damage of the normal tissue by the photothermal effect can be greatly avoided.

An injectable nanocomposite hydrogel co-constructed with gold nanorods and paclitaxel-loaded nanoparticles for local chemo-photothermal synergetic cancer therapy

2019 ◽  
Vol 7 (16) ◽  
pp. 2667-2677 ◽  
Author(s):  
Meiyan Liu ◽  
Pingsheng Huang ◽  
Weiwei Wang ◽  
Zujian Feng ◽  
Jianhua Zhang ◽  
...  
Keyword(s):  
Cancer Therapy ◽  
Gold Nanorods ◽  
Photothermal Therapy ◽  
Nanocomposite Hydrogel ◽  
Tumor Inhibition

A nanocomposite hydrogel, AuNR/PTXmPECTgel, was fabricated for in situ synergetic chemotherapy and photothermal therapy for tumor inhibition.

scholarly journals Simple synthesis of gold-decorated silica nanoparticles by in situ precipitation method with new plasmonic properties

2021 ◽  
Vol 3 (4) ◽  
Author(s):  
Lizbet León Félix ◽  
Joaquin Martinez Porcel ◽  
Fermín Fidel Herrera Aragón ◽  
David Gregorio Pacheco-Salazar ◽  
Marcelo Henrique Sousa
Keyword(s):  
Surface Plasmon Resonance ◽  
Silica Nanoparticles ◽  
Surface Plasmon ◽  
Plasmon Resonance ◽  
Photothermal Therapy ◽  
Precipitation Method ◽  
Ambient Conditions ◽  
Simple Method ◽  
Potential Applications

AbstractWe describe a simple method for the preparation of gold-decorated silica (SiO2) nanoparticles (NPs) by the in situ precipitation method using simple BH4− ions reduction as a procedure, where BH4− ions are adsorbed onto PEI-functionalized SiO2 NPs for stabilizing and reducing gold ions onto PEI-SiO2 surface in water under ambient conditions. The result was 3-nm gold nanoshell NPs attached to SiO2 core (~ 75 nm) with a surface plasmon resonance (SPR) at ~ 680 nm. SPR band is associated with Au NP aggregates that arise from strong interparticle interaction. This is an alternative to the gold-seeding methods and the use of anionic gold species for the obtention of gold-decorated SiO2 NPs with an important red-shift in UV–Vis absorption and with potential applications in biosensors and photothermal therapy.

Interferometric spectroscopy and high-speed orientation detection of individual gold nanorods

Nanoscale ◽  
2020 ◽  
Vol 12 (4) ◽  
pp. 2613-2625
Author(s):  
Zhixing He ◽  
Chengshuai Li ◽  
Hans D. Robinson ◽  
Yizheng Zhu
Keyword(s):  
Time Scales ◽  
Gold Nanorods ◽  
Plasmon Resonance ◽  
High Speed ◽  
Scattered Light ◽  
Resonance Wavelength ◽  
Gold Nanorod ◽  
Orientation Detection

The 3D orientation and plasmon resonance wavelength in a single gold nanorod are simultaneously characterized at microsecond time scales with an interferometric, spectroscopic polarimetry of scattered light.

scholarly journals Biomedical Applications of Nanomaterials: Diagnosis and Therapy of Thrombotic Disorders

2017 ◽  
Vol 53 (01) ◽  
pp. 036-040
Author(s):  
D. Dash
Keyword(s):  
Gold Nanorods ◽  
Photothermal Therapy ◽  
Biomedical Applications ◽  
Near Infrared ◽  
Infrared Laser ◽  
Coronary Risk ◽  
Innovative Strategy ◽  
Diagnosis And Therapy ◽  
Metallic Nanomaterials

ABSTRACTWe have employed unique properties of carbon-based as well as metallic nanomaterials to develop diagnostic / therapeutic devices targeted against thrombotic disorders. We have designed a novel graphene-based biosensor that can detect individuals with high coronary risk. Further, we describe an innovative strategy to ablate pathological thrombus in situ employing near-infrared laser-irradiated gold nanorods (photothermal therapy).

Theoretical Simulation of Temperature Elevations in Tumors Using Monte Carlo Method and Comparison to Experimental Measurements During Laser Photothermal Therapy

2013 ◽  
Author(s):  
Navid Manuchehrabadi ◽  
Yonghui Chen ◽  
Alexander LeBrun ◽  
Ronghui Ma ◽  
Liang Zhu
Keyword(s):  
Monte Carlo ◽  
Monte Carlo Method ◽  
Gold Nanorods ◽  
Photothermal Therapy ◽  
Treatment Protocol ◽  
Gold Nanorod ◽  
Theoretical Simulation ◽  
The Past ◽  
Geometric Ratio ◽  
Laser Photothermal Therapy

Nanotechnology using gold nanoshells or nanorods is a newly developed hyperthermia approach and has been tested in the past several years in cancer treatment.1–2 Gold nanorods have a diameter of ∼10 nm and an aspect ratio of approximately four. By varying the geometric ratio, the nanostructures can be tuned to have strong absorption and scattering to a specific laser wavelength. Designing an optimal treatment protocol of laser photothermal therapy requires understanding of gold nanorod deposition inside the tumor after injection, its resulted specific absorption rate (SAR) distribution, and the ultimate temperature field in the tumor during the treatment. Recent microCT studies by our group have suggested that the gold nanorod solution injected into PC3 prostatic tumors results in an almost uniform distribution of the gold nanorods in the tumors.3 The Monte Carlo method has been used in the past to determine the heating pattern (SAR) of laser-tissue thermal interaction.4 However, the accuracy of the theoretical simulation of the temperature fields in tumors relies on precise measurements of the optical properties of the tumors with nanorods presence.

scholarly journals Graphene Oxide-Coated Gold Nanorods: Synthesis and Applications

Nanomaterials ◽  
2020 ◽  
Vol 10 (11) ◽  
pp. 2149
Author(s):  
Thabang C. Lebepe ◽  
Sundararajan Parani ◽  
Oluwatobi S. Oluwafemi
Keyword(s):  
Graphene Oxide ◽  
Gold Nanorods ◽  
Photothermal Therapy ◽  
Ex Situ ◽  
Future Perspectives

The application of gold nanorods (AuNRs) and graphene oxide (GO) has been widely studied due to their unique properties. Although each material has its own challenges, their combination produces an exceptional material for many applications such as sensor, therapeutics, and many others. This review covers the progress made so far in the synthesis and application of GO-coated AuNRs (GO–AuNRs). Initially, it highlights different methods of synthesizing AuNRs and GO followed by two approaches (ex situ and in situ approaches) of coating AuNRs with GO. In addition, the properties of GO–AuNRs composite such as biocompatibility, photothermal profiling, and their various applications, which include photothermal therapy, theranostic, sensor, and other applications of GO–AuNRs are also discussed. The review concludes with challenges associated with GO–AuNRs and future perspectives.

Surface enhanced anti-Stokes one-photon luminescence from single gold nanorods

Nanoscale ◽  
2015 ◽  
Vol 7 (2) ◽  
pp. 577-582 ◽  
Author(s):  
Yingbo He ◽  
Keyu Xia ◽  
Guowei Lu ◽  
Hongming Shen ◽  
Yuqing Cheng ◽  
...  
Keyword(s):  
Surface Plasmon Resonance ◽  
Fermi Level ◽  
Surface Plasmon ◽  
Gold Nanorods ◽  
Plasmon Resonance ◽  
Gold Nanorod ◽  
Surface Enhanced ◽  
Anti Stokes

Anti-Stokes one-photon luminescence from single gold nanorod was determined to be enhanced by surface plasmon resonance and strongly related with the distribution of electrons near the Fermi level.

Rattle-Structured Rough Nanocapsules with in-Situ-Formed Gold Nanorod Cores for Complementary Gene/Chemo/Photothermal Therapy

ACS Nano ◽  
2018 ◽  
Vol 12 (6) ◽  
pp. 5646-5656 ◽  
Author(s):  
Xinyan Chen ◽  
Qing Zhang ◽  
Jinliang Li ◽  
Ming Yang ◽  
Nana Zhao ◽  
...  
Keyword(s):  
Photothermal Therapy ◽  
Gold Nanorod ◽  
Complementary Gene
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