Endogenous Cu in the central nervous system fails to satiate the elevated requirement for Cu in a mutant SOD1 mouse model of ALS
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It is unclear why ubiquitous expression of mutant SOD1 selectively affects the central nervous system in amyotrophic lateral sclerosis. Here we hypothesise that the central nervous system is primarily affected because, unlike other tissues, it has relatively limited capacity to satiate an increased requirement for Cu.
2004 ◽
Vol 120
(2)
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pp. 115-122
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1944 ◽
Vol 99
(6)
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pp. 973
2012 ◽
Vol 516
(2)
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pp. 296-301
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