scholarly journals Fabrication of a 3D Teflon microdevice for energy free homogeneous liquid flow inside a long microchannel and its application to continuous-flow PCR

RSC Advances ◽  
2017 ◽  
Vol 7 (18) ◽  
pp. 10624-10630 ◽  
Author(s):  
Kieu The Loan Trinh ◽  
Wenming Wu ◽  
Nae Yoon Lee

The 3D spiral PTFE microdevice was fabricated for performing continuous-flow PCR using a single heater and via semi-automated sample injection method.

2021 ◽  
Author(s):  
Amin Etminan ◽  
Yuri S. Muzychka ◽  
Kevin Pope

Abstract This paper presents a CFD-based simulation method for air/water and water/dodecane Taylor flows through an axisymmetric microchannel with a circular cross-sectional area. A systematic analysis is conducted by exploring the effects of different superficial velocities and apparent viscosities on the hydrodynamics of a slug flow regime. A concentric junction is employed to make bubbles of air in a continuous flow of water and slugs of water in a continuous flow of dodecane oil. A time-history study is conducted to predict the air-bubble and water-slug evolution processes, in particular at the moment of slug breakup. The results show that the larger apparent viscosity ratio of phases involved in the liquid-liquid flow generates a more stable interface. However, the liquid slug length is less and film thickness is slightly larger in liquid-liquid compared to gas-liquid flow. Furthermore, variations in gas and liquid holdups are correlated by the superficial velocity ratio. The numerical analysis developed in this paper is in good agreement with the correlations and data in the literature.


Lab on a Chip ◽  
2019 ◽  
Vol 19 (2) ◽  
pp. 214-222 ◽  
Author(s):  
Nan Xiang ◽  
Yu Han ◽  
Yuan Jia ◽  
Zhiguo Shi ◽  
Hong Yi ◽  
...  

We proposed a novel syringe flow-stabilizer for hand-powered, precise, continuous-flow microfluidic sample injection in resource-poor settings.


2015 ◽  
Vol 7 (1) ◽  
pp. 175-180 ◽  
Author(s):  
Cheng Chen ◽  
Lingchen Meng ◽  
Meixian Li ◽  
Zhiwei Zhu

A rapid, sensitive and cost-effective CE-UV method has been developed for the simultaneous separation and sensitive determination of four beta2-agonists.


2017 ◽  
Vol 2 (4) ◽  
pp. 498-511 ◽  
Author(s):  
Christian P. Haas ◽  
Tibor Müllner ◽  
Richard Kohns ◽  
Dirk Enke ◽  
Ulrich Tallarek

On-line control and monitoring in heterogeneous catalysis utilizing high-performance supports allows rapid screening of intrinsic reaction parameters in continuous-flow mode.


Author(s):  
Chang-Hwan Choi ◽  
Joonwon Kim ◽  
Chang-Jin Kim

We report nano-engineered surfaces (NanoTurf), designed to make various micro- and nano-fluidic devices and systems less frictional for liquid flows, and describe microchannels made with such a surface. While our group has reported a dramatic (> 95%) drag reduction of discrete droplets flowing in a space between two parallel-plates covered with “random” nano-posts created by the “black silicon method” [1], this paper describes various nanofabrication techniques, including those capable of “designing” nanostructures with not only a good control of pattern sizes and periods but also practical manufacturability to be embedded in various micro- and nano-fluidic devices and systems. Microchannels are developed using the designed nanostructure surfaces and used for continuous flow tests.


ACS Catalysis ◽  
2013 ◽  
Vol 3 (12) ◽  
pp. 2669-2676 ◽  
Author(s):  
Bernhard Gutmann ◽  
Petteri Elsner ◽  
Dominique Roberge ◽  
C. Oliver Kappe

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