Construction of polydopamine-coated gold nanostars for CT imaging and enhanced photothermal therapy of tumors: an innovative theranostic strategy

2016 ◽  
Vol 4 (23) ◽  
pp. 4216-4226 ◽  
Author(s):  
Du Li ◽  
Yongxing Zhang ◽  
Shihui Wen ◽  
Yang Song ◽  
Yueqin Tang ◽  
...  
Keyword(s):  
Photothermal Therapy ◽  
Ct Imaging ◽  
Gold Nanostars

A theranostic nanoplatform for in vivo CT imaging and enhanced PTT of tumors is reported.

Core-Shell Pd@Au Nanoplates as Theranostic Agents for In-Vivo Photoacoustic Imaging, CT Imaging, and Photothermal Therapy

2014 ◽  
Vol 26 (48) ◽  
pp. 8210-8216 ◽  
Author(s):  
Mei Chen ◽  
Shaoheng Tang ◽  
Zhide Guo ◽  
Xiaoyong Wang ◽  
Shiguang Mo ◽  
...  
Keyword(s):  
Photothermal Therapy ◽  
Photoacoustic Imaging ◽  
Ct Imaging ◽  
Core Shell ◽  
Theranostic Agents

PEGylated hollow gold nanoparticles for combined X-ray radiation and photothermal therapy in vitro and enhanced CT imaging in vivo

2019 ◽  
Vol 16 ◽  
pp. 195-205 ◽  
Author(s):  
Ru Wang ◽  
Junjie Deng ◽  
Dongsheng He ◽  
Ershuang Yang ◽  
Wenqian Yang ◽  
...  
Keyword(s):  
Gold Nanoparticles ◽  
Photothermal Therapy ◽  
Ct Imaging ◽  
X Ray ◽  
Hollow Gold Nanoparticles ◽  
Enhanced Ct

Liquid Exfoliation of Colloidal Rhenium Disulfide Nanosheets as a Multifunctional Theranostic Agent for In Vivo Photoacoustic/CT Imaging and Photothermal Therapy

Small ◽  
2018 ◽  
Vol 14 (14) ◽  
pp. 1703789 ◽  
Author(s):  
Zhao-Hua Miao ◽  
Lan-Xiang Lv ◽  
Kai Li ◽  
Pei-Ying Liu ◽  
Zhenglin Li ◽  
...  
Keyword(s):  
Photothermal Therapy ◽  
Ct Imaging ◽  
Liquid Exfoliation ◽  
Theranostic Agent

Gold nanostars functionalized with amine-terminated PEG for X-ray/CT imaging and photothermal therapy

2015 ◽  
Vol 3 (21) ◽  
pp. 4330-4337 ◽  
Author(s):  
Ying Tian ◽  
Song Luo ◽  
Huaijiang Yan ◽  
Zhaogang Teng ◽  
Yuanwei Pan ◽  
...  
Keyword(s):  
Photothermal Therapy ◽  
Ct Imaging ◽  
Ct Guided ◽  
X Ray ◽  
Gold Nanostars

We present the great potential of gold nanostars decorated with amine-terminated PEG in the application of X-ray/CT-guided photothermal therapy.

scholarly journals Untrasmall Bi2S3 nanodots for in vivo X-ray CT imaging-guided photothermal therapy of cancer

RSC Advances ◽  
2017 ◽  
Vol 7 (47) ◽  
pp. 29672-29678 ◽  
Author(s):  
Zelun Li ◽  
Kelong Ai ◽  
Zhe Yang ◽  
Tianqi Zhang ◽  
Jianhua Liu ◽  
...  
Keyword(s):  
Cancer Treatment ◽  
Real Time ◽  
Photothermal Therapy ◽  
Therapeutic Response ◽  
Ct Imaging ◽  
X Ray

Theranostic nanomedicine has shown tremendous promise for more effective and predictive cancer treatment by real-time mornitoring of the delivery of therapeutics to tumors and subsequent therapeutic response.

Dendrimer-Stabilized Gold Nanostars as a Multifunctional Theranostic Nanoplatform for CT Imaging, Photothermal Therapy, and Gene Silencing of Tumors

2016 ◽  
Vol 5 (24) ◽  
pp. 3203-3213 ◽  
Author(s):  
Ping Wei ◽  
Jingwen Chen ◽  
Yong Hu ◽  
Xin Li ◽  
Han Wang ◽  
...  
Keyword(s):  
Gene Silencing ◽  
Photothermal Therapy ◽  
Ct Imaging ◽  
Gold Nanostars

Na0.3WO3 nanorods: a multifunctional agent for in vivo dual-model imaging and photothermal therapy of cancer cells

2015 ◽  
Vol 44 (6) ◽  
pp. 2771-2779 ◽  
Author(s):  
Yuxin Zhang ◽  
Bo Li ◽  
Yunjiu Cao ◽  
Jinbao Qin ◽  
Zhiyou Peng ◽  
...  
Keyword(s):  
Cancer Cells ◽  
Photothermal Therapy ◽  
Ct Imaging ◽  
Dual Model ◽  
Photothermal Treatment ◽  
Nir Absorption

The hydrophilic Na0.3WO3 nanorods showed intense NIR absorption and large HU value, and thus can be used as a promising multifunctional agent for CT imaging and photothermal treatment of cancer.

scholarly journals Engineered Exosomes-Based Photothermal Therapy with MRI/CT Imaging Guidance Enhances Anticancer Efficacy through Deep Tumor Nucleus Penetration

Pharmaceutics ◽  
2021 ◽  
Vol 13 (10) ◽  
pp. 1593
Author(s):  
Min Yang ◽  
Xiaohui Wang ◽  
Fang Pu ◽  
Ying Liu ◽  
Jia Guo ◽  
...  
Keyword(s):  
Photothermal Therapy ◽  
Tumor Therapy ◽  
Ct Imaging ◽  
Cancer Site ◽  
Control Group ◽  
Anticancer Efficacy ◽  
In Vivo Experiments ◽  
Actual Application

Exosomes, as natural nanovesicles, have become a spotlight in the field of cancer therapy due to their reduced immunogenicity and ability to overcome physiological barriers. However, the tumor targeting ability of exosomes needs to be improved before its actual application. Herein, a multiple targeted engineered exosomes nanoplatform was constructed through rare earth element Gd and Dy-doped and TAT peptide-modified carbon dots (CDs:Gd,Dy-TAT) encapsulated into RGD peptide engineered exosomes (Exo-RGD), which were used to enhance the effect of cancer imaging diagnosis and photothermal therapy. In vitro and in vivo experiments showed that the resulting CDs:Gd,Dy-TAT@Exo-RGD could effectively accumulate at cancer site with an increased concentration owing to the targeting peptides modification and exosomes encapsulation. The tumor therapy effects of mice treated with CDs:Gd,Dy-TAT@Exo-RGD were heightened compared with mice from the CDs:Gd,Dy control group. After intravenous injection of CDs:Gd,Dy-TAT@Exo-RGD into tumor-bearing mice, the temperature of tumors rose to above 50 °C under NIR irradiation and the localized hyperpyrexia induced by CDs could remarkably ablate tumors. The survival rate of the mice was 100% after 60 days. In addition, the CDs:Gd,Dy-TAT@Exo-RGD exhibited higher MRI/CT imaging contrast enhancement of tumor sites than that of CDs:Gd,Dy. Our study identified that engineered exosomes are a powerful tool for encapsulating multiple agents to enhance cancer theranostic efficiency and provide insight into precise personalized nanomedicine.

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