Linear poly(ethylene imine)s: true molar masses, solution properties and conformation

2017 ◽  
Vol 8 (46) ◽  
pp. 7169-7179 ◽  
Author(s):  
Igor Perevyazko ◽  
Alexander S. Gubarev ◽  
Lutz Tauhardt ◽  
Anatoly Dobrodumov ◽  
Georges M. Pavlov ◽  
...  
Keyword(s):  
Gene Therapy ◽  
Pivotal Role ◽  
Polymer Chemistry ◽  
Solution Properties ◽  
Ethylene Imine ◽  
Linear Poly ◽  
Poly Ethylene

In-depth characterization of pharmaceutically relevant polymers plays a pivotal role in many areas, including nanoscience, gene therapy, analytical and polymer chemistry etc.

Linear Poly(ethylene imine)-Based Hydrogels for Effective Binding and Release of DNA

2014 ◽  
Vol 15 (4) ◽  
pp. 1124-1131 ◽  
Author(s):  
Christoph Englert ◽  
Lutz Tauhardt ◽  
Matthias Hartlieb ◽  
Kristian Kempe ◽  
Michael Gottschaldt ◽  
...  
Keyword(s):  
Ethylene Imine ◽  
Linear Poly ◽  
Poly Ethylene

scholarly journals Comparison of Linear Poly Ethylene Imine (LPEI) and Poly L-Lysine (PLL) in Fabrication of CHOK1 Cell-Loaded Multilayer Alginate Microcapsules

2020 ◽  
Vol 10 (2) ◽  
pp. 290-296
Author(s):  
Fariba Hajifathaliha ◽  
Arash Mahboubi ◽  
Elham Mohit ◽  
Noushin Bolourchian ◽  
Vahid Khalaj ◽  
...  
Keyword(s):  
Cell Viability ◽  
Cell Survival ◽  
Metabolic Activity ◽  
Encapsulation Efficiency ◽  
Cell Encapsulation ◽  
High Price ◽  
Ethylene Imine ◽  
Linear Poly ◽  
Cellular Metabolic Activity ◽  
Poly Ethylene

Purpose: Poly l-lysine (PLL) has been introduced as a strengthening covering layer for alginate microcapsules which are the most convenient way for cell encapsulation. Some disadvantages of PLL such as high price and low biocompatibility have prompted scientists to find better alternatives. Linear poly ethylene imine (LPEI), thanks to its highly similar structure to PLL, could be considered as a proper cost-effective alternative. In this study LPEI and PLL were compared as covering layers of cell-loaded alginate-LPEI-alginate (cALA) and alginate-PLL-alginate (cAPA) microcapsules. Methods: In addition to the physico-mechanical properties, the encapsulation efficiency, cell survival post encapsulation, cell viability, and cellular metabolic activity within the microcapsules were evaluated using trypan blue, live/dead cell staining, and MTT test, respectively. Results: Physico-mechanical evaluation of the microcapsules revealed that the cell microencapsulation process did not affect their shape, size, and mechanical stability. Although the encapsulation efficiency for cALA and cAPA was not different (P>0.05), cell survival post encapsulation was higher in cALA than in cAPA (P<0.05) which could be the reason for the higher cell viability and also cellular metabolic activity within these microcapsules in comparison to cAPA. Conclusion: Here, based on these results, ALA could be introduced as a preferable alternative to APA for cell encapsulation.

Dextran-graft-linear poly(ethylene imine)s for gene delivery: Importance of the linking strategy

2014 ◽  
Vol 113 ◽  
pp. 597-606 ◽  
Author(s):  
Sofia Ochrimenko ◽  
Antje Vollrath ◽  
Lutz Tauhardt ◽  
Kristian Kempe ◽  
Stephanie Schubert ◽  
...  
Keyword(s):  
Gene Delivery ◽  
Ethylene Imine ◽  
Linear Poly ◽  
Poly Ethylene

Calcium phosphate mineralization with linear poly(ethylene imine): a time-resolved study

2011 ◽  
Vol 289 (8) ◽  
pp. 881-888 ◽  
Author(s):  
Andriy Shkilnyy ◽  
Stefanie Schöne ◽  
Claudia Rumplasch ◽  
Annett Uhlmann ◽  
Annett Hedderich ◽  
...  
Keyword(s):  
Calcium Phosphate ◽  
Ethylene Imine ◽  
Time Resolved ◽  
Phosphate Mineralization ◽  
Linear Poly ◽  
Poly Ethylene

Charge Reversal of Sulfate Latex Particles by Adsorbed Linear Poly(ethylene imine) Probed by Multiparticle Colloidal Probe Technique

2011 ◽  
Vol 115 (29) ◽  
pp. 9098-9105 ◽  
Author(s):  
Marco Finessi ◽  
Prashant Sinha ◽  
István Szilágyi ◽  
Ionel Popa ◽  
Plinio Maroni ◽  
...  
Keyword(s):  
Ethylene Imine ◽  
Charge Reversal ◽  
Latex Particles ◽  
Probe Technique ◽  
Colloidal Probe ◽  
Linear Poly ◽  
Poly Ethylene

Linear Poly(ethylene imine)s by Acidic Hydrolysis of Poly(2-oxazoline)s: Kinetic Screening, Thermal Properties, and Temperature-Induced Solubility Transitions

2010 ◽  
Vol 43 (2) ◽  
pp. 927-933 ◽  
Author(s):  
Hanneke M. L. Lambermont-Thijs ◽  
Friso S. van der Woerdt ◽  
Anja Baumgaertel ◽  
Lies Bonami ◽  
Filip E. Du Prez ◽  
...  
Keyword(s):  
Thermal Properties ◽  
Ethylene Imine ◽  
Acidic Hydrolysis ◽  
Linear Poly ◽  
Poly Ethylene ◽  
Hydrolysis Of

Physicochemical Characterization of Thermoresponsive Poly(N-isopropylacrylamide)−poly(ethylene imine) Graft Copolymers

2008 ◽  
Vol 9 (4) ◽  
pp. 1170-1178 ◽  
Author(s):  
Peter C. Griffiths ◽  
Cameron Alexander ◽  
Renuka Nilmini ◽  
Sivanand S. Pennadam ◽  
Stephen M. King ◽  
...  
Keyword(s):  
Graft Copolymers ◽  
Physicochemical Characterization ◽  
Ethylene Imine ◽  
Poly Ethylene

Characterization of DNA/poly(ethylene imine) electrolyte membranes

2007 ◽  
Vol 15 (6) ◽  
pp. 581-586 ◽  
Author(s):  
Jin Kyoung Park ◽  
Jongok Won ◽  
Chan Kyung Kim
Keyword(s):  
Ethylene Imine ◽  
Electrolyte Membranes ◽  
Poly Ethylene
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