scholarly journals A novel silver-loaded chitosan composite sponge with sustained silver release as a long-lasting antimicrobial dressing

RSC Advances ◽  
2017 ◽  
Vol 7 (55) ◽  
pp. 34655-34663 ◽  
Author(s):  
Xiaofei Huang ◽  
Xiaojiong Bao ◽  
Zhengke Wang ◽  
Qiaoling Hu
Keyword(s):  
Wound Healing ◽  
Potential Candidate ◽  
Chitosan Matrix ◽  
Silver Release ◽  
Chitosan Composite

A new kind of chitosan-based sponge with sustained silver release was prepared by loading CCS-AgNPs into chitosan matrix through interaction between catechol and chitosan, which is considered as a potential candidate for wound healing dressings.

Polyvinyl Alcohol/Chitosan Composite Hydrogels with Sustained Release of Traditional Tibetan Medicine for Promoting Chronic Diabetic Wound Healing

2021 ◽  
Author(s):  
Xingyu Chen ◽  
Zuxin Wang ◽  
Shan Gao ◽  
Wanlin Zhang ◽  
Hanwen Gong ◽  
...  
Keyword(s):  
Wound Healing ◽  
Polyvinyl Alcohol ◽  
Sustained Release ◽  
Skin Diseases ◽  
Tibetan Medicine ◽  
Diabetic Wound ◽  
Composite Hydrogels ◽  
Diabetic Wound Healing ◽  
Traditional Tibetan Medicine ◽  
Chitosan Composite

The Tibetan eighteen flavor dangshen pills (TEP) are composed of 18 traditional Tibetan medicines, which are commonly used in the treatment of skin diseases in the Tibetan medicine system. They...

Fabrication of hydroxyapatite/chitosan composite hydrogels loaded with exosomes derived from miR-126-3p overexpressed synovial mesenchymal stem cells for diabetic chronic wound healing

2016 ◽  
Vol 4 (42) ◽  
pp. 6830-6841 ◽  
Author(s):  
Min Li ◽  
Qin-Fei Ke ◽  
Shi-Cong Tao ◽  
Shang-Chun Guo ◽  
Bi-Yu Rui ◽  
...  
Keyword(s):  
Stem Cells ◽  
Wound Healing ◽  
Mesenchymal Stem Cells ◽  
Chronic Wound ◽  
Wound Surface ◽  
Composite Hydrogels ◽  
Chitosan Composite

Hydroxyapatite/chitosan composite hydrogels loaded with exosomes was fabricated for promoting wound surface re-epithelialization, angiogenesis, collagen maturity and diabetic chronic wound healing.

Preparation and Characterization of Polylactic Acid Fiber Enhanced Hydroxyapatite/Chitosan Composites

2011 ◽  
Vol 368-373 ◽  
pp. 321-325
Author(s):  
Hai Rong Yin ◽  
Quan Xian Zu ◽  
Yang Wu
Keyword(s):  
Polylactic Acid ◽  
Composite Plate ◽  
Influence Factors ◽  
Orthogonal Test ◽  
Pecking Order ◽  
Bending Modulus ◽  
Chitosan Matrix ◽  
Ft Ir ◽  
And Performance ◽  
Chitosan Composite

A novel hydroxyapatite/chitosan composite plate enhanced by polylactic acid fiber is prepared via in–situ hybridization in the semipermeable mold. The influence factors of the composites are evaluated by orthogonal test; FT–IR, XRD and SEM are also used to determine the relevance between the composition and performance. Analyses show that: hydroxyapatite with weak crystalline state is generated in the composites; there is hydrogen bonding associating existing in the complex system; preferable interface junction is created between the fiber and hydroxyapatite /chitosan matrix, which is able to play benign potentiation to the mechanical strength. Orthogonal test finds that the pecking order of the influencing factors to physical properties is: fiber content > fiber length > hydroxyapatite content. HA/CS composite plate enhanced by PLA–fiber can get a significantly increase on flexural strength and bending modulus, therefore, it will be a kind of potential orthopaedic materials which possesses the ability of completely degraded.

Effect of Juglone on Migration of Human Ovarian Cancer SKOV3 Cells

2014 ◽  
Vol 912-914 ◽  
pp. 1911-1914
Author(s):  
Liang Zhong Zhao ◽  
Shuang Chen ◽  
Qing Fang ◽  
Duo Zhang ◽  
You Peng Zhu ◽  
...  
Keyword(s):  
Ovarian Cancer ◽  
Wound Healing ◽  
Plant Species ◽  
Human Ovarian Cancer ◽  
Skov3 Cell ◽  
Potential Candidate ◽  
Wound Healing Assay ◽  
Skov3 Cells ◽  
Anti Cancer ◽  
Cancer Activity

Juglone is isolated from many plant species belonging to Juglandaceae family. Recent studies have shown that Juglone exhibits various bioactivities including anti-tumor functions. However, its anti-cancer activity on human ovarian cancer SKOV3 cell has not been examined. Thus, the current study was designed to elucidate the effect of Juglone on migration of human ovarian cancer SKOV3 cells. In the present study, SKOV3 cells were incubated with Juglone at various concentrations. Wound healing assay and Transwell chambers were used to detect migration of SKOV3 treated with Juglone for 24h. The result showed that Juglone inhibited the migration of SKOV3 cells with concentration of Juglone at 25, 50 or 100μM compared with control cells. Therefore, our results indicated that Juglone may be a potential candidate of drug for ovarian cancer.

scholarly journals Ulmus Parvifolia Accelerate Skin Wound Healing by Regulating the Expression of MMPs and TGF-β

2019 ◽  
Author(s):  
Min Cheol Kang ◽  
Silvia Yumnam ◽  
Woo Sung Park ◽  
Hae Min So ◽  
Ki Hyun Kim ◽  
...  
Keyword(s):  
Wound Healing ◽  
Growth Factor ◽  
Transforming Growth Factor ◽  
Skin Wound ◽  
Root Bark ◽  
Potential Candidate ◽  
Skin Wound Healing ◽  
Healing Effect ◽  
Ulmus Parvifolia ◽  
Wound Healing Effect

Ulmus species have been widely used in Korean folk medicine because of their anti-inflammatory and antimicrobial properties. We intended to investigate the wound healing effect of the powder of Ulmus parvifolia (UP) root bark in a mouse wound healing model. We also determined the mechanisms of effects of Ulmus parvifolia (UP) in skin and skin wound healing effect using keratinocyte model. in vivo experiments showed that the wound lesions in the mice decreased by U. parvifolia with 200 mesh size of root bark powder and significantly reduced by treatment with UP, compared with those treated with U. macrocarpa (UM). Results from in vitro experiments also revealed that UP extract promoted the migration of human skin keratinocytes. UP powder treatment upregulated the expression of the matrix metalloproteinase-2 and -9 protein and significantly increased transforming growth factor (TGF)-β levels. We confirmed that topical administration of the bark powder of exerted a significant effect on skin wound healing by upregulating the expression of MMP and transforming growth factor-β. TGF-β In, Our study suggests that U. parvifolia may be a potential candidate for skin wound healing including epidermal skin rejuvernation.

Chitosan composite hydrogels cross‐linked by multifunctional diazo resin as antibacterial dressings for improved wound healing

2020 ◽  
Vol 108 (9) ◽  
pp. 1890-1898 ◽  
Author(s):  
Lilong Gao ◽  
Hui Zhang ◽  
Bing Yu ◽  
Wenlong Li ◽  
Fei Gao ◽  
...  
Keyword(s):  
Wound Healing ◽  
Composite Hydrogels ◽  
Chitosan Composite

scholarly journals The Conductance and Swelling of Composite Membrane ‘Chitosan-Silver Nanoparticles’ in Monovalent Salt Solution ‘KCl and NaCl’

2019 ◽  
Vol 20 (2) ◽  
pp. 1
Author(s):  
Ni Wayan Eri Sandriani ◽  
Ni Nyoman Rupiasih ◽  
Made Sumadiyasa
Keyword(s):  
Composite Membrane ◽  
Membrane Conductance ◽  
Absorption Capacity ◽  
Water Absorption Capacity ◽  
Nacl Solution ◽  
Salt Solutions ◽  
Chitosan Matrix ◽  
Chitosan Membrane ◽  
Monovalent Salt ◽  
Chitosan Composite

A research about to determine the conductance and water absorption capacity (swelling) of the composite membrane has been conducted. The membrane used was a membrane made of chitosan matrix, silver nanoparticle(AgNP) of 100 µg as a filler and acetic acid 1% as a solvent, which named chitosan composite membrane (Ch-AgNP). A 2% chitosan membrane (membrane Ch) used as a comparison. The membrane conductance value determined by measuring the membrane voltage (V) as a function of current (I) in monovalent salt solutions of NaCl and KCl with a concentration of 0.025 M. The swelling tests have been carried out using distilled water. The results showed that Ch membrane conductance was greater than the Ch-AgNP composite membrane. In KCl solution, the conductance is 0.0991 ?-1 and 0.0984 ?-1 and in NaCl solution are 0.1002 ?-1 and 0.0996 ?-1. The membrane conductance is greater in NaCl solution than in KCl solution. The swelling test showed that the swelling percentage of Ch-AgNP composite membrane was greater than Ch membrane

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