Precise control of drug loading and release of an NSAID–polymer conjugate for long term osteoarthritis intra-articular drug delivery

2017 ◽  
Vol 5 (31) ◽  
pp. 6221-6226 ◽  
Author(s):  
Adrian Sulistio ◽  
Felisa Reyes-Ortega ◽  
Asha M. D’Souza ◽  
Sarah M. Y. Ng ◽  
David Valade ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Drug Loading ◽  
Biocompatible Polymer ◽  
High Drug ◽  
Precise Control ◽  
Polymer Conjugate ◽  
Degree Of Control ◽  
High Degree ◽  
High Drug Loading

The synthesis of biocompatible polymer diclofenac conjugates (PDCs) that have a high drug loading and high degree of control over diclofenac (DCF) release is described.

Prodrugs Forming High Drug Loading Multifunctional Nanocapsules for Intracellular Cancer Drug Delivery

2010 ◽  
Vol 132 (12) ◽  
pp. 4259-4265 ◽  
Author(s):  
Youqing Shen ◽  
Erlei Jin ◽  
Bo Zhang ◽  
Caitlin J. Murphy ◽  
Meihua Sui ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Drug Loading ◽  
Cancer Drug ◽  
High Drug ◽  
Cancer Drug Delivery ◽  
High Drug Loading

A novel high drug loading mussel-inspired polydopamine hybrid nanoparticle as a pH-sensitive vehicle for drug delivery

2017 ◽  
Vol 533 (1) ◽  
pp. 73-83 ◽  
Author(s):  
Jie Hou ◽  
Chunlei Guo ◽  
Yuzhi Shi ◽  
Ergang Liu ◽  
Weibing Dong ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Drug Loading ◽  
Ph Sensitive ◽  
High Drug ◽  
Hybrid Nanoparticle ◽  
High Drug Loading

scholarly journals A facile doxorubicin-dichloroacetate conjugate nanomedicine with high drug loading for safe drug delivery

2018 ◽  
Vol Volume 13 ◽  
pp. 1281-1293 ◽  
Author(s):  
Conglian Yang ◽  
Tingting Wu ◽  
Yuting Qin ◽  
Yan Qi ◽  
Yu Sun ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Drug Loading ◽  
High Drug ◽  
High Drug Loading

A γ-cyclodextrin-based metal–organic framework embedded with graphene quantum dots and modified with PEGMA via SI-ATRP for anticancer drug delivery and therapy

Nanoscale ◽  
2019 ◽  
Vol 11 (43) ◽  
pp. 20956-20967 ◽  
Author(s):  
Qiaojuan Jia ◽  
Zhenzhen Li ◽  
Chuanpan Guo ◽  
Xiaoyu Huang ◽  
Yingpan Song ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Metal Organic Framework ◽  
Drug Loading ◽  
Graphene Quantum Dots ◽  
Tumor Growth Inhibition ◽  
High Drug ◽  
Anticancer Drug Delivery ◽  
Metal Organic ◽  
High Drug Loading

A biocompatible γ-CD-MOF based DDS with high drug loading and full drug release was prepared and effective tumor growth inhibition was achieved in vivo.

Supramolecular micellar drug delivery system based on multi-arm block copolymer for highly effective encapsulation and sustained-release chemotherapy

2019 ◽  
Vol 7 (37) ◽  
pp. 5677-5687 ◽  
Author(s):  
Li Zhang ◽  
Dongjian Shi ◽  
Chunling Shi ◽  
Tatsuo Kaneko ◽  
Mingqing Chen
Keyword(s):  
Drug Delivery ◽  
Block Copolymer ◽  
Sustained Release ◽  
Drug Delivery System ◽  
Delivery System ◽  
Drug Loading ◽  
High Drug ◽  
Release Drug ◽  
Drug Loading Efficiency ◽  
High Drug Loading

A novel multi-arm polyphosphoester-based nanomaterial provides high drug loading efficiency and sustained-release drug delivery for effective chemotherapy.

Stimuli-responsive poly(ionic liquid) nanoparticles for controlled drug delivery

2020 ◽  
Vol 8 (35) ◽  
pp. 7994-8001 ◽  
Author(s):  
Beibei Lu ◽  
Gaoxin Zhou ◽  
Fan Xiao ◽  
Qianjun He ◽  
Jiaheng Zhang
Keyword(s):  
Drug Delivery ◽  
Ionic Liquid ◽  
Drug Loading ◽  
Controlled Drug Delivery ◽  
Stimuli Responsive ◽  
Spherical Nanoparticles ◽  
High Drug ◽  
Good Ability ◽  
Poly Ionic Liquid ◽  
High Drug Loading

A novel poly(ionic liquid) (PIL)-based block copolymer, which can self-assemble into spherical nanoparticles, high drug loading content, and good ability to inhibit tumors. Therefore, this copolymer shows great potential for drug delivery. 

scholarly journals Synthesis and compatibility evaluation of versatile mesoporous silica nanoparticles with red blood cells: an overview

RSC Advances ◽  
2019 ◽  
Vol 9 (61) ◽  
pp. 35566-35578 ◽  
Author(s):  
Subhankar Mukhopadhyay ◽  
Hanitrarimalala Veroniaina ◽  
Tadious Chimombe ◽  
Lidong Han ◽  
Wu Zhenghong ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Mesoporous Silica ◽  
Silica Nanoparticles ◽  
Blood Cells ◽  
Drug Delivery Systems ◽  
Mesoporous Silica Nanoparticles ◽  
Drug Loading ◽  
Loading Capacity ◽  
High Drug ◽  
High Drug Loading

Protean mesoporous silica nanoparticles are propitious candidates over decades for nanoscale drug delivery systems due to their unique characteristics, including changeable pore size, mesoporosity, high drug loading capacity and biodegradability.

Construction of High Drug Loading and Enzymatic Degradable Multilayer Films for Self-Defense Drug Release and Long-Term Biofilm Inhibition

2017 ◽  
Vol 19 (1) ◽  
pp. 85-93 ◽  
Author(s):  
Bailiang Wang ◽  
Huihua Liu ◽  
Lin Sun ◽  
Yingying Jin ◽  
Xiaoxu Ding ◽  
...  
Keyword(s):  
Drug Release ◽  
Drug Loading ◽  
Multilayer Films ◽  
Biofilm Inhibition ◽  
High Drug ◽  
Self Defense ◽  
High Drug Loading
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