scholarly journals Continuous monitoring of adenosine and its metabolites using microdialysis coupled to microchip electrophoresis with amperometric detection

2018 ◽  
Vol 10 (30) ◽  
pp. 3737-3744 ◽  
Author(s):  
Shamal M. Gunawardhana ◽  
Susan M. Lunte
Keyword(s):  
Continuous Monitoring ◽  
Amperometric Detection ◽  
Microchip Electrophoresis ◽  
Working Electrode ◽  
On Line ◽  
Line Analysis ◽  
Pdms Device

Reversibly sealed all-PDMS device with CF working electrode for continuous on-line analysis of microdialysis samples.

A Mobile Laser Mass Spectrometer (REMPI-TOFMS) for Continuous Monitoring of Toxic Combustion Byproducts: Real-time On-line Analysis of PAH in Waste Incineration Flue Gases

1998 ◽  
Vol 134 (1-6) ◽  
pp. 87-101 ◽  
Author(s):  
R. Zimmermann ◽  
H. J. Heger ◽  
R. Dorfner ◽  
U. Boesl ◽  
M. Blumenstock ◽  
...  
Keyword(s):  
Real Time ◽  
Mass Spectrometer ◽  
Continuous Monitoring ◽  
Waste Incineration ◽  
Flue Gases ◽  
On Line ◽  
Laser Mass Spectrometer ◽  
Line Analysis

scholarly journals Microfabricated On-Line Sensor for Continuous Monitoring of L-Glutamate.

1998 ◽  
Vol 14 (5) ◽  
pp. 947-953 ◽  
Author(s):  
Osamu NIWA ◽  
Tsutomu HORIUCHI ◽  
Ryoji KURITA ◽  
Hisao TABEI ◽  
Keiichi TORIMITSU
Keyword(s):  
Continuous Monitoring ◽  
On Line

First on-line analysis of petroleum from single inclusion using ultrafast laser ablation

2010 ◽  
Vol 41 (2) ◽  
pp. 74-77 ◽  
Author(s):  
Herbert Volk ◽  
David Fuentes ◽  
Alexander Fuerbach ◽  
Christopher Miese ◽  
Wolfgang Koehler ◽  
...  
Keyword(s):  
Laser Ablation ◽  
Ultrafast Laser ◽  
Single Inclusion ◽  
On Line ◽  
Line Analysis ◽  
Ultrafast Laser Ablation

On-Line Analysis of Gas-Phase Composition in the Combustion Chamber and Particle Emission Characteristics during Combustion of Wood and Waste in a Small Batch Reactor

2005 ◽  
Vol 39 (6) ◽  
pp. 1393-1402 ◽  
Author(s):  
T. Ferge ◽  
J. Maguhn ◽  
K. Hafner ◽  
F. Mühlberger ◽  
M. Davidovic ◽  
...  
Keyword(s):  
Phase Composition ◽  
Combustion Chamber ◽  
Gas Phase ◽  
Batch Reactor ◽  
Particle Emission ◽  
Emission Characteristics ◽  
On Line ◽  
Line Analysis

On-line Flow Cytometry for Real-time Surgical Guidance

Neurosurgery ◽  
2004 ◽  
Vol 55 (3) ◽  
pp. 551-561 ◽  
Author(s):  
Ali H. Mesiwala ◽  
Louis D. Scampavia ◽  
Peter S. Rabinovitch ◽  
Jaromir Ruzicka ◽  
Robert C. Rostomily
Keyword(s):  
Decision Making ◽  
Real Time ◽  
Dna Content ◽  
Time Frame ◽  
Tissue Samples ◽  
Surgical Decision ◽  
Surgical Guidance ◽  
On Line ◽  
Surgical Decision Making ◽  
Line Analysis

Abstract OBJECTIVE: This study tests the feasibility of using on-line analysis of tissue during surgical resection of brain tumors to provide biologically relevant information in a clinically relevant time frame to augment surgical decision making. For the purposes of establishing feasibility, we used measurement of deoxyribonucleic acid (DNA) content as the end point for analysis. METHODS: We investigated the feasibility of interfacing an ultrasonic aspiration (USA) system with a flow cytometer (FC) capable of analyzing DNA content (DNA-FC). The sampling system design, tissue preparation requirements, and time requirements for each step of the on-line analysis system were determined using fresh beef brain tissue samples. We also compared DNA-FC measurements in 28 nonneoplastic human brain samples with DNA-FC measurements in specimens of 11 glioma patients obtained from central tumor regions and surgical margins after macroscopically gross total tumor removal to estimate the potential for analysis of a biological marker to influence surgical decision making. RESULTS: With minimal modification, modern FC systems are fully capable of real-time, intraoperative analysis of USA specimens. The total time required for on-line analysis of USA specimens varies between 36 and 63 seconds; this time includes delivery from the tip of the USA to complete analysis of the specimen. Approximately 60% of this time is required for equilibration of the DNA stain. When compared with values for nonneoplastic human brain samples, 50% of samples (10 of 20) from macroscopically normal glioma surgical margins contained DNA-FC abnormalities potentially indicating residual tumor. CONCLUSION: With an interface of existing technologies, DNA content of brain tissue samples can be analyzed in a meaningful time frame that has the potential to provide real-time information for surgical guidance. The identification of DNA content abnormalities in macroscopically normal tumor resection margins by DNA-FC supports the practical potential for on-line analysis of a tumor marker to guide surgical resections. The development of such a device would provide neurosurgeons with an objective method for intraoperative analysis of a clinically relevant biological parameter that can be measured in real time.

Possibility of on-line analysis of very short-lived nuclei with the aid of a spectrograph equipped with a laser ion source

1976 ◽  
Vol 135 (1) ◽  
pp. 111-116 ◽  
Author(s):  
J.F. Eloy ◽  
J.P. Zirnheld
Keyword(s):  
Ion Source ◽  
Laser Ion Source ◽  
On Line ◽  
Line Analysis
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