A facile two-photon fluorescent probe: an endoplasmic reticulum tracker monitoring ER stress and vesicular transport to lysosomes

2019 ◽  
Vol 55 (3) ◽  
pp. 294-297 ◽  
Author(s):  
Pratibha Kumari ◽  
Sanjay K. Verma ◽  
Shaikh M. Mobin
Keyword(s):  
Endoplasmic Reticulum ◽  
Er Stress ◽  
Fluorescent Probe ◽  
Vesicular Transport ◽  
Living Cells ◽  
Vesicle Transport ◽  
Live Cells ◽  
Tumor Spheroids ◽  
Dynamic Changes ◽  
Two Photon

The two-photon fluorescent organic probe ERLp selectively labels the endoplasmic reticulum in live cells and tumor spheroids. ERLp can also monitor ER dynamic changes during ER stress and vesicle transport from the ER to the lysosome in living cells.

Visualization of vesicular transport from the endoplasmic reticulum to lysosome using an amidine derived two-photon probe

2017 ◽  
Vol 53 (45) ◽  
pp. 6097-6100 ◽  
Author(s):  
Hyo Won Lee ◽  
Myoung Ki Cho ◽  
Hye-Ri Kim ◽  
Chang Su Lim ◽  
Chulhun Kang ◽  
...  
Keyword(s):  
Endoplasmic Reticulum ◽  
Fluorescent Probe ◽  
Small Molecule ◽  
Vesicular Transport ◽  
Vesicle Transport ◽  
Live Cells ◽  
Two Photon

An amidine-based small molecule two-photon fluorescent probe for monitoring vesicle transport from the ER to lysosome in live cells was reported.

A two-photon endoplasmic reticulum-targeting fluorescent probe for the imaging of pH in living cells and zebrafish

2018 ◽  
Vol 10 (47) ◽  
pp. 5702-5706 ◽  
Author(s):  
Nan Zhang ◽  
Baoli Dong ◽  
Xiuqi Kong ◽  
Wenhui Song ◽  
Weiying Lin
Keyword(s):  
Endoplasmic Reticulum ◽  
Fluorescent Probe ◽  
Living Cells ◽  
Ph Changes ◽  
Two Photon ◽  
Endoplasmic Reticulum Targeting

The pH changes of the endoplasmic reticulum (ER) are closely related to many diseases.

A two-photon fluorescent probe for bio-imaging of formaldehyde in living cells and tissues

The Analyst ◽  
2016 ◽  
Vol 141 (11) ◽  
pp. 3395-3402 ◽  
Author(s):  
Jun-Bin Li ◽  
Qian-Qian Wang ◽  
Lin Yuan ◽  
Yong-Xiang Wu ◽  
Xiao-Xiao Hu ◽  
...  
Keyword(s):  
Fluorescent Probe ◽  
Living Cells ◽  
Live Cells ◽  
Two Photon ◽  
Bio Imaging

We report a new two-photon fluorescent probe FATP1 that allows for the two-photon bio-imaging of formaldehyde in live cells and tissues.

Development of an endoplasmic reticulum-targeting fluorescent probe for the two-photon imaging of hypochlorous acid (HClO) in living cells

2019 ◽  
Vol 11 (35) ◽  
pp. 4450-4455 ◽  
Author(s):  
Wenhui Song ◽  
Baoli Dong ◽  
Yaru Lu ◽  
Xiuqi Kong ◽  
Abdul Hadi Mehmood ◽  
...  
Keyword(s):  
Reactive Oxygen Species ◽  
Endoplasmic Reticulum ◽  
Cell Death ◽  
Fluorescent Probe ◽  
Hypochlorous Acid ◽  
Living Cells ◽  
Oxygen Species ◽  
Cell Dysfunction ◽  
Two Photon ◽  
Endoplasmic Reticulum Targeting

As an important reactive oxygen species, hypochlorous acid (HClO) could irreversibly destroy Ca2+-ATPase to inhibit Ca2+ transport in the endoplasmic reticulum (ER), which may eventually lead to cell dysfunction and cell death.

An endoplasmic reticulum-targeting fluorescent probe for imaging ˙OH in living cells

2020 ◽  
Vol 56 (47) ◽  
pp. 6344-6347 ◽  
Author(s):  
Yanyan Zhao ◽  
Hongyu Li ◽  
Ziyin Chai ◽  
Wen Shi ◽  
Xiaohua Li ◽  
...  
Keyword(s):  
Endoplasmic Reticulum ◽  
Er Stress ◽  
Fluorescent Probe ◽  
Lipid Droplet ◽  
Droplet Formation ◽  
Living Cells ◽  
Lipid Droplet Formation ◽  
Er Targeting ◽  
Endoplasmic Reticulum Targeting

A new ER-targeting fluorescent probe for ˙OH is developed and applied to imaging ˙OH generation as well as lipid droplet formation in ER stress.

Achieving the ratiometric imaging of steroid sulfatase in living cells and tissues with a two-photon fluorescent probe

2020 ◽  
Vol 56 (9) ◽  
pp. 1349-1352 ◽  
Author(s):  
Wei Li ◽  
Shulu Yin ◽  
Xiangyang Gong ◽  
Wang Xu ◽  
Ronghua Yang ◽  
...  
Keyword(s):  
Endoplasmic Reticulum ◽  
Fluorescent Probe ◽  
Living Cells ◽  
Fluorescence Assay ◽  
Steroid Sulfatase ◽  
Ratiometric Fluorescence ◽  
Two Photon ◽  
Ratiometric Imaging ◽  
Endogenous Steroid

A novel two-photon ratiometric fluorescence assay was proposed for monitoring endogenous steroid sulfatase (STS) activity, which achieved the ratiometric imaging of STS activity in the endoplasmic reticulum of living cells and tissues.

A smart mitochondria-targeting TP-NIR fluorescent probe for selective and sensitive sensing H2S in living cells and mice

2021 ◽  
Author(s):  
Qiaomei Yang ◽  
Liyi Zhou ◽  
Longpeng Peng ◽  
Gangqiang Yuan ◽  
Haiyuan Ding ◽  
...  
Keyword(s):  
Hydrogen Sulfide ◽  
Fluorescent Probe ◽  
Near Infrared ◽  
Living Cells ◽  
Signal Molecules ◽  
Two Photon ◽  
Mitochondria Targeting

Hydrogen sulfide (H2S) is one of the important gaseous signal molecules and plays key roles in various biologically crucial processes. In this work, we report a novel two-photon near-infrared (TP-NIR)...

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