Designing dual-functionalized carbon nanotubes with high blood–brain-barrier permeability for precise orthotopic glioma therapy

2019 ◽  
Vol 48 (5) ◽  
pp. 1569-1573 ◽  
Author(s):  
Yuanyuan You ◽  
Ni Wang ◽  
Lizhen He ◽  
Changzheng Shi ◽  
Dong Zhang ◽  
...  
Keyword(s):  
Carbon Nanotubes ◽  
Carbon Nanotube ◽  
Blood Brain Barrier ◽  
Cell Penetrating Peptide ◽  
Functionalized Carbon Nanotubes ◽  
Multi Walled Carbon Nanotube ◽  
Brain Barrier Permeability ◽  
Cell Penetrating ◽  
A Cell ◽  
Orthotopic Glioma

Herein we synthesize a cell penetrating peptide- and cancer-targeted molecule-functionalized multi-walled carbon nanotube for precise orthotopic glioma therapy.

Synthesis and Characterization of Poly(2,5-benzimidazole) (ABPBI) Grafted Carbon Nanotubes

2009 ◽  
Vol 1240 ◽  
Author(s):  
Ji-Ye Kang ◽  
Su-Mi Eo ◽  
Loon-Seng Tan ◽  
Jong-Beom Baek
Keyword(s):  
Carbon Nanotubes ◽  
Carbon Nanotube ◽  
Interfacial Adhesion ◽  
Synthesis And Characterization ◽  
Acylation Reaction ◽  
Single Walled Carbon Nanotube ◽  
Mechanical And Electrical Properties ◽  
Multi Walled Carbon Nanotube

AbstractSingle-walled carbon nanotube (SWCNT) and multi-walled carbon nanotube (MWCNT) were functionalized with 3,4-diaminobenzoic acid via “direct” Friedel-Crafts acylation reaction in PPA/P2O5 to afford ortho-diamino-functionalized SWCNT (DIF-SWCNT) and MWCNT (DIF-MWCNT). The resultant DIF-SWCNT and DIF-MWCNT showed improved solubility and dispersibility. To improve interfacial adhesion between CNT and polymer matrix, the grafting of ABPBI onto the surface of DIF-SWCNT (10 wt%) or DIF-MWCNT (10 wt%) was conducted by simple in-situ polymerization of AB monomer, 3,4-diaminobenzoic acid dihydrochloride, in PPA. The resultant ABPBI-g-MWCNT and ABPBI-g-SWCNT showed improved the mechanical and electrical properties.

Mechanical Properties Of Polyaniline / Multi-walled Carbon Nanotube Composite Films

2003 ◽  
Vol 791 ◽  
Author(s):  
P. C. Ramamurthy ◽  
W. R. Harrell ◽  
R. V. Gregory ◽  
B. Sadanadan ◽  
A. M. Rao
Keyword(s):  
Mechanical Properties ◽  
Carbon Nanotubes ◽  
Carbon Nanotube ◽  
Composite Films ◽  
Weight Percent ◽  
Organic Electronic Devices ◽  
Multiwalled Carbon ◽  
Multi Walled Carbon Nanotube ◽  
Contact Devices ◽  
Carbon Nanotube Composite

ABSTRACTHigh molecular weight polyaniline / multi-walled carbon nanotube composite films were fabricated using solution processing. Composite films with various weight percentages of multiwalled carbon nanotubes were fabricated. Physical properties of these composites were analyzed by thermogravimetric analysis, tensile testing, and scanning electron microscopy. These results indicate that the addition of multiwalled nanotubes to polyaniline significantly enhances the mechanical properties of the films. In addition, metal–semiconductor (composite) (MS) contact devices were fabricated, and it was observed that the current level in the films increased with increasing multiwalled nanotube content. Furthermore, it was observed that polyaniline containing one weight percent of carbon nanotubes appears to be the most promising composition for applications in organic electronic devices.

scholarly journals A Cell-Penetrating Peptide with a Guanidinylethyl Amine Structure Directed to Gene Delivery

2016 ◽  
Vol 6 (1) ◽  
Author(s):  
Makoto Oba ◽  
Takuma Kato ◽  
Kaori Furukawa ◽  
Masakazu Tanaka
Keyword(s):  
Gene Delivery ◽  
Cell Penetrating Peptide ◽  
Cell Penetrating ◽  
Amine Structure ◽  
A Cell

Pharmacokinetics, Biodistribution, Stability and Toxicity of a Cell-Penetrating Peptide−Morpholino Oligomer Conjugate

2007 ◽  
Vol 18 (4) ◽  
pp. 1325-1331 ◽  
Author(s):  
Adams Amantana ◽  
Hong M. Moulton ◽  
Melissa L. Cate ◽  
Muralimohan T. Reddy ◽  
Tom Whitehead ◽  
...  
Keyword(s):  
Cell Penetrating Peptide ◽  
Cell Penetrating ◽  
A Cell
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