An AceDAN–porphyrin(Zn) dyad for fluorescence imaging and photodynamic therapy via two-photon excited FRET

2018 ◽  
Vol 5 (12) ◽  
pp. 3061-3066 ◽  
Author(s):  
Mengliang Zhu ◽  
Chaorui Su ◽  
Peipei Xing ◽  
Yabin Zhou ◽  
Lei Gong ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Singlet Oxygen ◽  
Cancer Cells ◽  
Fluorescence Imaging ◽  
Red Emission ◽  
Two Photon

A FRET based AceDAN–porphyrin(Zn) dyad was designed to generate red emission and singlet oxygen (1O2) simultaneously, which were utilized successfully for two-photon excited fluorescence imaging and PDT of cancer cells.

scholarly journals Biocompatible conjugated fluorenylporphyrins for two-photon photodynamic therapy and fluorescence imaging

2019 ◽  
Vol 55 (81) ◽  
pp. 12231-12234 ◽  
Author(s):  
Limiao Shi ◽  
Christophe Nguyen ◽  
Morgane Daurat ◽  
Abdelhamid Chiheb Dhieb ◽  
Wajda Smirani ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Photodynamic Therapy ◽  
Cancer Cells ◽  
Fluorescence Imaging ◽  
Breast Cancer Cells ◽  
Two Photon ◽  
Theranostic Applications

Three new biocompatible porphyrin-based oxygen photosensitisers were tested in vitro on breast cancer cells via 2P-PDT: one of them, 66 times more active than H2TPP, gave quite promising results for theranostic applications.

scholarly journals A multifunctional nanoprobe for targeting tumors and mitochondria with singlet oxygen generation and monitoring mitochondrion pH changes in cancer cells by ratiometric fluorescence imaging

2020 ◽  
Vol 11 (14) ◽  
pp. 3636-3643 ◽  
Author(s):  
Jingjin Zhao ◽  
Mengbing Zou ◽  
Mengjiao Huang ◽  
Liangliang Zhang ◽  
Keqin Yang ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Singlet Oxygen ◽  
Cancer Cells ◽  
Fluorescence Imaging ◽  
Ratiometric Fluorescence ◽  
Oxygen Generation ◽  
Ph Changes ◽  
Singlet Oxygen Generation ◽  
Multifunctional Nanoprobe

A multifunctional nanoprobe with singlet oxygen generation that can target tumors and mitochondria was developed for photodynamic therapy of tumors and monitoring mitochondrion pH changes in cancer cells by ratiometric fluorescence imaging.

A biotinylated ruthenium(ii) photosensitizer for tumor-targeted two-photon photodynamic therapy

2019 ◽  
Vol 55 (73) ◽  
pp. 10972-10975 ◽  
Author(s):  
Jia Li ◽  
Leli Zeng ◽  
Kai Xiong ◽  
Thomas W. Rees ◽  
Chengzhi Jin ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Singlet Oxygen ◽  
Cancer Cells ◽  
Cisplatin Resistance ◽  
Two Photon ◽  
Target Cancer

A biotinylated ruthenium(ii) two-photon photosensitizer was developed to selectively target cancer cells and overcome cisplatin resistance by the production of high levels of singlet oxygen.

Lysosomal targeted NIR photosensitizer for photodynamic therapy and two-photon fluorescent imaging

2021 ◽  
Author(s):  
Ruiyuan Liu ◽  
Yuping Zhou ◽  
Di Zhang ◽  
Genghan He ◽  
Chuang Liu ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Fluorescence Imaging ◽  
Near Infrared ◽  
Fluorescent Imaging ◽  
High Fidelity ◽  
Design And Synthesis ◽  
Two Photon ◽  
Two Photon Fluorescence ◽  
Photon Fluorescence

Design and synthesis of near-infrared (NIR) emissive fluorophore for imaging of organelle and photodynamic therapy has received enormous attention. Hence, NIR emissive fluorophore of high-fidelity lysosome targeting, two-photon fluorescence imaging,...

scholarly journals Design, synthesis and application in biological imaging of a novel red fluorescent dye based on a rhodanine derivative

RSC Advances ◽  
2021 ◽  
Vol 11 (1) ◽  
pp. 160-163
Author(s):  
Zijing Li ◽  
Bin Huang ◽  
Yuan Wang ◽  
Wenbo Yuan ◽  
Yijing Wu ◽  
...  
Keyword(s):  
Cancer Cells ◽  
Fluorescence Imaging ◽  
Inhibitory Concentration ◽  
Fluorescent Dye ◽  
Biological Imaging ◽  
Design Synthesis ◽  
Red Emission ◽  
Rhodanine Derivative

2RDNTPA can be applied in fluorescence imaging of living cancer cells (HepG2) with red emission of 620 nm and negligible cytotoxicity with a half maximal inhibitory concentration much more than 100 μM.

Biocompatible fluorenylphthalocyanines for one and two-photon photodynamic therapy and fluorescence imaging

2021 ◽  
pp. 109840
Author(s):  
Seifallah Abid ◽  
Christophe Nguyen ◽  
Morgane Daurat ◽  
Denis Durand ◽  
Bassem Jamoussi ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Fluorescence Imaging ◽  
Two Photon

Enhanced Two-Photon Fluorescence Imaging and Therapy of Cancer Cells via Gold@Bridged Silsesquioxane Nanoparticles

Small ◽  
2014 ◽  
Vol 11 (3) ◽  
pp. 295-299 ◽  
Author(s):  
Jonas Croissant ◽  
Marie Maynadier ◽  
Olivier Mongin ◽  
Vincent Hugues ◽  
Mireille Blanchard-Desce ◽  
...  
Keyword(s):  
Cancer Cells ◽  
Fluorescence Imaging ◽  
Two Photon ◽  
Bridged Silsesquioxane ◽  
Two Photon Fluorescence ◽  
Photon Fluorescence

A lysosome-targeted near-infrared photosensitizer for photodynamic therapy and two-photon fluorescence imaging

2021 ◽  
Author(s):  
Yinuo Tu ◽  
Weikang Xia ◽  
Xu Wu ◽  
Lei Wang
Keyword(s):  
Photodynamic Therapy ◽  
Fluorescence Imaging ◽  
Near Infrared ◽  
Two Photon ◽  
Two Photon Fluorescence ◽  
Photon Fluorescence

Organelle-targeted two-photon near-infrared photosensitizers are highly desirable for photodynamic therapy (PDT) of cancer. Herein, in this contribution, we have developed a 2-dicyanomethylenethiazole based D-π-A structured near-infrared photosensitizer (TTR). TTR depicts...

scholarly journals Highly efficient singlet oxygen generation, two-photon photodynamic therapy and melanoma ablation by rationally designed mitochondria-specific near-infrared AIEgens

2020 ◽  
Vol 11 (9) ◽  
pp. 2494-2503 ◽  
Author(s):  
Zheng Zheng ◽  
Haixiang Liu ◽  
Shaodong Zhai ◽  
Haoke Zhang ◽  
Guogang Shan ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Singlet Oxygen ◽  
Near Infrared ◽  
Molecular Engineering ◽  
Photon Absorption ◽  
Oxygen Generation ◽  
Two Photon Absorption ◽  
Two Photon ◽  
Singlet Oxygen Generation ◽  
Highly Efficient

Mitochondria-targeted photosensitizers with highly efficient singlet oxygen generation, bright near-infrared AIE and good two-photon absorption are obtained through ingenious molecular engineering for cancer cell-selective photodynamic therapy.

Absorption-dependent generation of singlet oxygen from gold bipyramids excited under low power density

RSC Advances ◽  
2015 ◽  
Vol 5 (100) ◽  
pp. 81897-81904 ◽  
Author(s):  
Junliang Lv ◽  
Xin Zhang ◽  
Nana Li ◽  
Baoju Wang ◽  
Sailing He
Keyword(s):  
Photodynamic Therapy ◽  
Low Power ◽  
Singlet Oxygen ◽  
Cancer Cells ◽  
Power Density ◽  
Oxygen Generation ◽  
Singlet Oxygen Generation ◽  
Photodynamic Therapy Of Cancer

Gold bipyramid-mediated singlet oxygen generation for photodynamic therapy of cancer cells in the optical biological window.

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