Biocompatible fluorenylphthalocyanines for one and two-photon photodynamic therapy and fluorescence imaging

2021 ◽  
pp. 109840
Author(s):  
Seifallah Abid ◽  
Christophe Nguyen ◽  
Morgane Daurat ◽  
Denis Durand ◽  
Bassem Jamoussi ◽  
...  
Author(s):  
Ruiyuan Liu ◽  
Yuping Zhou ◽  
Di Zhang ◽  
Genghan He ◽  
Chuang Liu ◽  
...  

Design and synthesis of near-infrared (NIR) emissive fluorophore for imaging of organelle and photodynamic therapy has received enormous attention. Hence, NIR emissive fluorophore of high-fidelity lysosome targeting, two-photon fluorescence imaging,...


Author(s):  
Yinuo Tu ◽  
Weikang Xia ◽  
Xu Wu ◽  
Lei Wang

Organelle-targeted two-photon near-infrared photosensitizers are highly desirable for photodynamic therapy (PDT) of cancer. Herein, in this contribution, we have developed a 2-dicyanomethylenethiazole based D-π-A structured near-infrared photosensitizer (TTR). TTR depicts...


2019 ◽  
Vol 55 (81) ◽  
pp. 12231-12234 ◽  
Author(s):  
Limiao Shi ◽  
Christophe Nguyen ◽  
Morgane Daurat ◽  
Abdelhamid Chiheb Dhieb ◽  
Wajda Smirani ◽  
...  

Three new biocompatible porphyrin-based oxygen photosensitisers were tested in vitro on breast cancer cells via 2P-PDT: one of them, 66 times more active than H2TPP, gave quite promising results for theranostic applications.


2017 ◽  
Vol 5 (20) ◽  
pp. 3651-3657 ◽  
Author(s):  
Shaojing Zhao ◽  
Guangle Niu ◽  
Feng Wu ◽  
Li Yan ◽  
Hongyan Zhang ◽  
...  

Polythiophene nanoparticles with large TPA cross section and high1O2generation quantum yield have been developed for simultaneous lysosome-targetable fluorescence imaging and photodynamic therapy.


2018 ◽  
Vol 5 (12) ◽  
pp. 3061-3066 ◽  
Author(s):  
Mengliang Zhu ◽  
Chaorui Su ◽  
Peipei Xing ◽  
Yabin Zhou ◽  
Lei Gong ◽  
...  

A FRET based AceDAN–porphyrin(Zn) dyad was designed to generate red emission and singlet oxygen (1O2) simultaneously, which were utilized successfully for two-photon excited fluorescence imaging and PDT of cancer cells.


2018 ◽  
Vol 9 (4) ◽  
pp. 999-1005 ◽  
Author(s):  
Wenbo Hu ◽  
Meng Xie ◽  
Hui Zhao ◽  
Yufu Tang ◽  
Song Yao ◽  
...  

A nitric oxide (NO) activatable photosensitizer was constructed for efficient fluorescence imaging and photodynamic therapy.


2020 ◽  
Vol 8 (19) ◽  
pp. 6342-6349 ◽  
Author(s):  
Liang Xu ◽  
Junzheng Zhang ◽  
Lingfeng Yin ◽  
Xueting Long ◽  
Wenying Zhang ◽  
...  

The enhancement of two-photon absorption cross-section, fluorescence quantum yield and singlet oxygen generation efficiency for organic dyes and their applications in two-photon excited fluorescence imaging and photodynamic therapy are summarized.


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