scholarly journals Antiproliferative activities of tricyclic amides derived from β-caryophyllene via the Ritter reaction against MDA-MB-231 breast cancer cells

2020 ◽  
Vol 11 (1) ◽  
pp. 118-124 ◽  
Author(s):  
XiXi Xu ◽  
Ariane Roseblade ◽  
Tristan Rawling ◽  
Alison T. Ung
Keyword(s):  
Breast Cancer ◽  
Cell Cycle ◽  
Cell Death ◽  
Breast Cancer Cells ◽  
Cell Cycle Progression ◽  
Apoptotic Cell ◽  
Ritter Reaction ◽  
Cycle Progression ◽  
The Ritter Reaction ◽  
Antiproliferative Activities

Tricyclic amides were successfully synthesised from β-caryophyllene via the Ritter reaction. Amides 3c and 6b inhibited proliferation of MDA-MB-231 cells. Compound 6b inhibited cell cycle progression and induced predominantly apoptotic cell death.

scholarly journals Δ9-Tetrahydrocannabinol Inhibits Cell Cycle Progression in Human Breast Cancer Cells through Cdc2 Regulation

2006 ◽  
Vol 66 (13) ◽  
pp. 6615-6621 ◽  
Author(s):  
María M. Caffarel ◽  
David Sarrió ◽  
José Palacios ◽  
Manuel Guzmán ◽  
Cristina Sánchez
Keyword(s):  
Breast Cancer ◽  
Cell Cycle ◽  
Cancer Cells ◽  
Human Breast Cancer ◽  
Breast Cancer Cells ◽  
Cell Cycle Progression ◽  
Human Breast Cancer Cells ◽  
Human Breast ◽  
Cycle Progression
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