Direct 3D printing of a tough hydrogel incorporated with carbon nanotubes for bone regeneration

2019 ◽  
Vol 7 (45) ◽  
pp. 7207-7217 ◽  
Author(s):  
Haomin Cui ◽  
Yaling Yu ◽  
Xiaokeng Li ◽  
Ziyang Sun ◽  
Jihao Ruan ◽  
...  

The emerging three-dimensional (3D) printing technique has shown prominent advantages to fabricate hydrogel-based tissue scaffolds for the regeneration of bone defects.

2019 ◽  
Vol 822 ◽  
pp. 277-283
Author(s):  
Mariia Stepanova ◽  
Aleksei Eremin ◽  
Ilia Averianov ◽  
Iosif Gofman ◽  
Antonina Lavrentieva ◽  
...  

Supermacroporous three-dimensional matrices based on poly-D,L-lactide or polycaprolactone were fabricated by thermally induced phase separation method and 3D printing technique. The morphology and mechanical properties of the resulting matrices were studied with the use of optical and scanning electron microscopy and the uniaxial compression test, respectively. All matrices were characterized with supermacroporous structure suitable for cell penetration. A significant increase in Young's modulus and tensile strength was established for both polymer matrices prepared by 3D printing technique.


Author(s):  
Peng Wang ◽  
Wei Chu ◽  
Wenbo Li ◽  
Yuanxin Tan ◽  
Fang Liu ◽  
...  

Three-dimensional (3D) printing has allowed for production of geometrically complex 3D objects with extreme flexibility, which is currently undergoing rapid expansions in terms of materials, functionalities, as well as areas of application. When attempting to print 3D microstructures in glass, femtosecond laser induced chemical etching (FLICE) – which is a subtractive 3D printing technique – has proved itself a powerful approach. Here, we demonstrate fabrication of macro-scale 3D glass objects of large heights up to ~3.8 cm with an identical lateral and longitudinal spatial resolution of ~20 μm. The remarkable accomplishment is achieved by revealing an unexplored regime in the interaction of ultrafast laser pulses with fused silica which results in aberration-free focusing of the laser pulses deeply inside fused silica.


2020 ◽  
Author(s):  
Ruyi Zou ◽  
Min Wu ◽  
Jianzhong Guan ◽  
Yuzhou Xiao ◽  
Xiaotian Chen

Abstract Background To explore the clinical efficacy of pararectus approach combined with 3D printing technique for the surgical treatment of partial complex acetabular fractures. Methods We retrospectively evaluated 18 (11 males and 7 females) patients with complicated acetabular fractures in the period of June 2017 to December 2018; According to judet-letenneal classification: 11 cases were of double column fracture, 6 fractures were of the anterior column with posterior half transverse, and 1 case was of "T" fracture. For all cases, 3D printing is used to print the acetabular model. Pre-bent reconstruction plates from the model were placed to fixate fractures after reduction via the pararectus approach. Results The average time of surgery was 203 min (range:135-245 min)and mean intraoperative blood loss was 1030ml(range:450-1400ml);18 patients were followed up for 12-18 months (average,14 months);One patient (5.6%) developed postoperative wound infection, and the wound completely improved by secretion culture, enhanced dressing and effective antibiotics. One patient (5.6%) developed postoperative ossifying myositis, and there are no obvious symptoms at present; all patients underwent pelvic films and pelvic CT+ three-dimensional reconstruction after surgery, suggesting that fractures reduction as well. All the acetabular fractures united after 12 to 16 weeks(average,13 weeks);According to the modified Merle d’Aubigne and Postel scoring system to assess the hip function: excellent in 13 cases (72.2%), good in 3 cases(16.7%) and fair in 2 cases(11.1%). Conclusions In the treatment of partial complex acetabular fractures, the pararectus approach combined with 3D printing technique can achieve effective reduction and fixation, decrease intraoperative hemorrhage, shorten operation time and the internal fixation position can be properly adjusted during the operation by looking directly at the model.


Materials ◽  
2019 ◽  
Vol 12 (3) ◽  
pp. 504 ◽  
Author(s):  
Qiusheng Wang ◽  
Guocong Han ◽  
Shuqin Yan ◽  
Qiang Zhang

Three-dimensional (3D) printing is regarded as a critical technological-evolution in material engineering, especially for customized biomedicine. However, a big challenge that hinders the 3D printing technique applied in biomedical field is applicable bioink. Silk fibroin (SF) is used as a biomaterial for decades due to its remarkable high machinability and good biocompatibility and biodegradability, which provides a possible alternate of bioink for 3D printing. In this review, we summarize the requirements, characteristics and processabilities of SF bioink, in particular, focusing on the printing possibilities and capabilities of bioink. Further, the current achievements of cell-loading SF based bioinks were comprehensively viewed from their physical properties, chemical components, and bioactivities as well. Finally, the emerging issues and prospects of SF based bioink for 3D printing are given. This review provides a reference for the programmable and multiple processes and the further improvement of silk-based biomaterials fabrication by 3D printing.


2019 ◽  
Vol 47 (11) ◽  
pp. 5873-5882
Author(s):  
Linglong Deng ◽  
Xing Zhao ◽  
Chi Wei ◽  
Wenqiang Qu ◽  
Li Yu ◽  
...  

Chondrosarcoma is characterized by the presence of histologically aggressive behavior, and commonly involves the scapula. Currently, limb salvage surgery is the recommended surgical treatment. Owing to the irregularity of the tumor, the suitability of an implant after tumor resection is a challenge for surgeons. Three-dimensional (3D) printing technology has the potential to make personalized limb salvage surgery a reality. We report the case of a 53-year-old man who was diagnosed with chondrosarcoma of the scapula. Considering the low-grade malignancy and lack of invasion of the glenoid, we agreed upon segmental scapula replacement as the treatment protocol. Nevertheless, reconstruction of the irregular bony defect remaining after tumor resection can be complicated. Therefore, a personalized prosthesis and navigation template corresponding to tumor was designed with 3D printing technique, and tumor resection, prosthesis implantation, and rotator cuff reconstruction were completed. The affected shoulder achieved satisfactory function during a 32-month follow-up with no tumor recurrence. 3D printing technique can help implement the individualized design of the implant and accurate reconstruction after tumor resection, simplify complicated operations, improve operational efficiency, and allow early functional recovery.


RSC Advances ◽  
2016 ◽  
Vol 6 (3) ◽  
pp. 2450-2454 ◽  
Author(s):  
Carmen R. Tubío ◽  
José A. Nóvoa ◽  
Jorge Martín ◽  
Francisco Guitián ◽  
José R. Salgueiro ◽  
...  

A simple 3D printing technique is used to fabricate three-dimensional photonic crystals made of Al2O3 and intended to be functional for terahertz frequencies. The process is completed by a thermal sintering to obtain compact structures.


RSC Advances ◽  
2021 ◽  
Vol 11 (9) ◽  
pp. 5128-5138
Author(s):  
Ji Li ◽  
Ketao Wang ◽  
Xiaowei Bai ◽  
Qi Wang ◽  
Ningyu Lv ◽  
...  

Porous Ti6AI4V scaffolds incorporated with MSC and PRP are more effective in enhancing the bone regeneration.


ACS Omega ◽  
2019 ◽  
Vol 4 (7) ◽  
pp. 12012-12017 ◽  
Author(s):  
Elmeri Lahtinen ◽  
Lotta Turunen ◽  
Mikko M. Hänninen ◽  
Kalle Kolari ◽  
Heikki M. Tuononen ◽  
...  

Sign in / Sign up

Export Citation Format

Share Document