scholarly journals Application of a three-dimensional printed segmental scapula prosthesis in the treatment of scapula tumors

2019 ◽  
Vol 47 (11) ◽  
pp. 5873-5882
Author(s):  
Linglong Deng ◽  
Xing Zhao ◽  
Chi Wei ◽  
Wenqiang Qu ◽  
Li Yu ◽  
...  
Keyword(s):  
3D Printing ◽  
Limb Salvage ◽  
Salvage Surgery ◽  
Tumor Resection ◽  
Three Dimensional ◽  
Limb Salvage Surgery ◽  
Bony Defect ◽  
Low Grade ◽  
Printing Technique ◽  
3D Printing Technique

Chondrosarcoma is characterized by the presence of histologically aggressive behavior, and commonly involves the scapula. Currently, limb salvage surgery is the recommended surgical treatment. Owing to the irregularity of the tumor, the suitability of an implant after tumor resection is a challenge for surgeons. Three-dimensional (3D) printing technology has the potential to make personalized limb salvage surgery a reality. We report the case of a 53-year-old man who was diagnosed with chondrosarcoma of the scapula. Considering the low-grade malignancy and lack of invasion of the glenoid, we agreed upon segmental scapula replacement as the treatment protocol. Nevertheless, reconstruction of the irregular bony defect remaining after tumor resection can be complicated. Therefore, a personalized prosthesis and navigation template corresponding to tumor was designed with 3D printing technique, and tumor resection, prosthesis implantation, and rotator cuff reconstruction were completed. The affected shoulder achieved satisfactory function during a 32-month follow-up with no tumor recurrence. 3D printing technique can help implement the individualized design of the implant and accurate reconstruction after tumor resection, simplify complicated operations, improve operational efficiency, and allow early functional recovery.

Bone tumor resection guide using three-dimensional printing for limb salvage surgery

2018 ◽  
Vol 118 (6) ◽  
pp. 898-905 ◽  
Author(s):  
Jong Woong Park ◽  
Hyun Guy Kang ◽  
Kwun Mook Lim ◽  
Dae Woo Park ◽  
June Hyuk Kim ◽  
...  
Keyword(s):  
Limb Salvage ◽  
Bone Tumor ◽  
Salvage Surgery ◽  
Tumor Resection ◽  
Three Dimensional ◽  
Limb Salvage Surgery ◽  
Three Dimensional Printing ◽  
Bone Tumor Resection ◽  
Dimensional Printing

Comparison of Supermacroporous Polyester Matrices Fabricated by Thermally Induced Phase Separation and 3D Printing Techniques

2019 ◽  
Vol 822 ◽  
pp. 277-283
Author(s):  
Mariia Stepanova ◽  
Aleksei Eremin ◽  
Ilia Averianov ◽  
Iosif Gofman ◽  
Antonina Lavrentieva ◽  
...  
Keyword(s):  
Phase Separation ◽  
3D Printing ◽  
Three Dimensional ◽  
Uniaxial Compression Test ◽  
Thermally Induced Phase Separation ◽  
Cell Penetration ◽  
Thermally Induced ◽  
Printing Technique ◽  
3D Printing Technique ◽  
Printing Techniques

Supermacroporous three-dimensional matrices based on poly-D,L-lactide or polycaprolactone were fabricated by thermally induced phase separation method and 3D printing technique. The morphology and mechanical properties of the resulting matrices were studied with the use of optical and scanning electron microscopy and the uniaxial compression test, respectively. All matrices were characterized with supermacroporous structure suitable for cell penetration. A significant increase in Young's modulus and tensile strength was established for both polymer matrices prepared by 3D printing technique.

scholarly journals Three-Dimensional Laser Printing of Macro-Scale Glass Objects at a Micro-Scale Resolution

2019 ◽  
Author(s):  
Peng Wang ◽  
Wei Chu ◽  
Wenbo Li ◽  
Yuanxin Tan ◽  
Fang Liu ◽  
...  
Keyword(s):  
3D Printing ◽  
Three Dimensional ◽  
Laser Pulses ◽  
Fused Silica ◽  
Ultrafast Laser Pulses ◽  
3D Objects ◽  
Macro Scale ◽  
Powerful Approach ◽  
Printing Technique ◽  
3D Printing Technique

Three-dimensional (3D) printing has allowed for production of geometrically complex 3D objects with extreme flexibility, which is currently undergoing rapid expansions in terms of materials, functionalities, as well as areas of application. When attempting to print 3D microstructures in glass, femtosecond laser induced chemical etching (FLICE) – which is a subtractive 3D printing technique – has proved itself a powerful approach. Here, we demonstrate fabrication of macro-scale 3D glass objects of large heights up to ~3.8 cm with an identical lateral and longitudinal spatial resolution of ~20 μm. The remarkable accomplishment is achieved by revealing an unexplored regime in the interaction of ultrafast laser pulses with fused silica which results in aberration-free focusing of the laser pulses deeply inside fused silica.

scholarly journals Therapeutic effect of acetabular fractures using the Pararectus approach combined with 3D printing technique

2020 ◽  
Author(s):  
Ruyi Zou ◽  
Min Wu ◽  
Jianzhong Guan ◽  
Yuzhou Xiao ◽  
Xiaotian Chen
Keyword(s):  
3D Printing ◽  
Three Dimensional ◽  
Operation Time ◽  
Acetabular Fractures ◽  
Effective Reduction ◽  
Printing Technique ◽  
Dimensional Reconstruction ◽  
Hip Function ◽  
Pararectus Approach ◽  
3D Printing Technique

Abstract Background To explore the clinical efficacy of pararectus approach combined with 3D printing technique for the surgical treatment of partial complex acetabular fractures. Methods We retrospectively evaluated 18 (11 males and 7 females) patients with complicated acetabular fractures in the period of June 2017 to December 2018; According to judet-letenneal classification: 11 cases were of double column fracture, 6 fractures were of the anterior column with posterior half transverse, and 1 case was of "T" fracture. For all cases, 3D printing is used to print the acetabular model. Pre-bent reconstruction plates from the model were placed to fixate fractures after reduction via the pararectus approach. Results The average time of surgery was 203 min (range:135-245 min)and mean intraoperative blood loss was 1030ml(range:450-1400ml);18 patients were followed up for 12-18 months (average,14 months);One patient (5.6%) developed postoperative wound infection, and the wound completely improved by secretion culture, enhanced dressing and effective antibiotics. One patient (5.6%) developed postoperative ossifying myositis, and there are no obvious symptoms at present; all patients underwent pelvic films and pelvic CT+ three-dimensional reconstruction after surgery, suggesting that fractures reduction as well. All the acetabular fractures united after 12 to 16 weeks(average,13 weeks);According to the modified Merle d’Aubigne and Postel scoring system to assess the hip function: excellent in 13 cases (72.2%), good in 3 cases(16.7%) and fair in 2 cases(11.1%). Conclusions In the treatment of partial complex acetabular fractures, the pararectus approach combined with 3D printing technique can achieve effective reduction and fixation, decrease intraoperative hemorrhage, shorten operation time and the internal fixation position can be properly adjusted during the operation by looking directly at the model.

Low-Grade Intraosseous Osteosarcoma With Prominent Lymphoid Infiltrate

2000 ◽  
Vol 124 (6) ◽  
pp. 868-871
Author(s):  
Mary L. Ostrowski ◽  
Mark E. Johnson ◽  
Paula D. Smith ◽  
Patricia Chevez-Barrios ◽  
Harlan J. Spjut
Keyword(s):  
Malignant Lymphoma ◽  
Limb Salvage ◽  
Salvage Surgery ◽  
Good Prognosis ◽  
Initial Diagnosis ◽  
Limb Salvage Surgery ◽  
Low Grade ◽  
Lymphoid Infiltrate ◽  
Flow Cytometric ◽  
Well Differentiated

Abstract Low-grade intraosseous osteosarcoma is an uncommon and well-differentiated osteosarcoma with a good prognosis. We report a proximal tibial low-grade intraosseous osteosarcoma with a prominent intratumoral lymphoid infiltrate, which led to an initial diagnosis of probable malignant lymphoma. The importance of this infiltrate, which exhibited reactive features on flow cytometric studies, is not known. Our patient is free of tumor 1 year after limb salvage surgery, without hematologic or lymphoid abnormalities.

scholarly journals Treatment-Related Prognostic Factors in Managing Osteosarcoma around the Knee with Limb Salvage Surgery: A Lesson from a Long-Term Follow-Up Study

2019 ◽  
Vol 2019 ◽  
pp. 1-13 ◽  
Author(s):  
Jianping Hu ◽  
Chunlin Zhang ◽  
Kunpeng Zhu ◽  
Lei Zhang ◽  
Tao Cai ◽  
...  
Keyword(s):  
Overall Survival ◽  
Prognostic Factors ◽  
Local Recurrence ◽  
Limb Salvage ◽  
Salvage Surgery ◽  
Survival Rates ◽  
Tumor Resection ◽  
Limb Salvage Surgery ◽  
Related Factors

Purpose. The aim of this study was to assess the treatment-related factors associated with local recurrence and overall survival of patients with osteosarcoma treated with limb-salvage surgery. Patients and Methods. Treatment-related factors were analyzed to evaluate their effects on local recurrence-free survival (LRFS) and overall survival (OS) in 182 patients from 2004 to 2013. Results. The mean length of follow-up was 73.4 ± 34.7 months (median, 68 months; range, 12-173 months), and 63 patients died by the end of the follow-up. The 5-year and 10-year overall survival rates were 68.6 ± 6.6% and 59.4 ± 10.6%, respectively. Univariate analysis showed that treatment-related prognostic factors for overall survival were prolonged symptom intervals >=60 days, biopsy/tumor resection performed by different centers, previous medical history, incomplete preoperative chemotherapy (<8 weeks), and prolonged postoperative interval >21 days. In the multivariate analysis, biopsy/tumor resection performed by different centers, incomplete implementation of planned new adjuvant chemotherapy, and delayed resumption of postoperative chemotherapy (>21 days) were risk factors for poor prognosis; biopsy/tumor resection performed by different centers and tumor necrosis <90% were independent predictors of local recurrence. Conclusion. For localized osteosarcoma treated with limb-salvage surgery, it is necessary to optimize timely standard chemotherapy and to resume postoperative chemotherapy to improve survival rates. Biopsies should be performed at experienced institutions in cases of developing local recurrence.

scholarly journals Surgical Technique and Outcome of Joint Sparing Limb Salvage Surgery by Three-dimensional-printed Prothesis for Children With Osteosarcoma in Distal Femur

2020 ◽  
Author(s):  
Tao Cai ◽  
Chunlin Zhang ◽  
Lei Zhang ◽  
Kunpeng Zhu ◽  
Jianping Hu ◽  
...  
Keyword(s):  
Surgical Technique ◽  
Limb Salvage ◽  
Distal Femur ◽  
Salvage Surgery ◽  
Three Dimensional ◽  
Limb Length Discrepancy ◽  
Limb Salvage Surgery ◽  
3D Printed ◽  
The Mean

Abstract Purpose The purpose of this study was to introduce the surgical technique and functional outcome of joint-sparing limb salvage surgery with metaphyseal osteotomy by dependent design of three-dimensional printed prothesis for children with osteosarcoma in distal femur.Methods Between 2012 to 2019, we performed twelve joint sparing limb salvage surgeries (JSLSS) with metaphyseal osteotomy for the children of osteosarcoma in the distal femur with our dependent design of 3D-printed guided plate and prothesis. The clinical assessment including resection margin, limb-length discrepancy, orthopaedic complications and functional outcome would be analyzed.Results The mean operation time for JSLSS was 107.6 minutes and the average blood loss was 194.5ml with the dependent design of 3D-printed prosthesis. With the assistance of guide plate, the mean margin of the osteosarcoma from the epiphyseal plate was 1.6 cm and the mean limb-length discrepancy was 2.2 cm with maximum follow-up period of seven years (mean 45.3 months, range 12-84 months). All the patients could bend their knee through >90° flexion, achieved similar results for ROMs in 6DOF during gait compared with normal data of Chinese knees, and the mean MSTS score was 94.7 for the patients with JSLSS. One patient had a superficial infection and there was one patient of local recurrence happened during the follow-up with the necrosis rate less than 90% by preoperative chemotherapy. None aseptic loosening happened in distal femur for the patients in this group with dependent design of 3D-printed prosthesis.Conclusion Joint-sparing limb salvage surgery by metaphyseal osteotomy with the dependent design of 3D-printed prosthesis and guide plate would be a good choice for the children with osteosarcoma in distal femur.

scholarly journals Surgical Technique and Outcome of Joint Sparing Limb Salvage Surgery by Three-Dimensional-Printed Prothesis for Children with Osteosarcoma in Distal Femur

2020 ◽  
Author(s):  
Tao Cai ◽  
Chunlin Zhang ◽  
Lei Zhang ◽  
Kunpeng Zhu ◽  
Jianping Hu ◽  
...  
Keyword(s):  
Surgical Technique ◽  
Limb Salvage ◽  
Distal Femur ◽  
Salvage Surgery ◽  
Three Dimensional ◽  
Limb Length Discrepancy ◽  
Limb Salvage Surgery ◽  
3D Printed ◽  
The Mean

Abstract Purpose The purpose of this study was to introduce the surgical technique and functional outcome of joint-sparing limb salvage surgery with metaphyseal osteotomy by dependent design of three-dimensional printed prothesis for children with osteosarcoma in distal femur.Methods Between 2012 to 2019, we performed twelve joint sparing limb salvage surgeries (JSLSS) with metaphyseal osteotomy for the children of osteosarcoma in the distal femur with our dependent design of 3D-printed guided plate and prothesis. The clinical assessment including resection margin, limb-length discrepancy, orthopaedic complications and functional outcome would be analyzed.Results The mean operation time for JSLSS was 107.6 minutes and the average blood loss was 194.5ml with the dependent design of 3D-printed prosthesis. With the assistance of guide plate, the mean margin of the osteosarcoma from the epiphyseal plate was 1.6 cm and the mean limb-length discrepancy was 2.2 cm with maximum follow-up period of seven years (mean 45.3 months, range 12-84 months). All the patients could bend their knee through >90° flexion, achieved similar results for ROMs in 6DOF during gait compared with normal data of Chinese knees, and the mean MSTS score was 94.7 for the patients with JSLSS. One patient had a superficial infection and there was one patient of local recurrence happened during the follow-up with the necrosis rate less than 90% by preoperative chemotherapy. None aseptic loosening happened in distal femur for the patients in this group with dependent design of 3D-printed prosthesis.Conclusion Joint-sparing limb salvage surgery by metaphyseal osteotomy with the dependent design of 3D-printed prosthesis and guide plate would be a good choice for the children with osteosarcoma in distal femur.

scholarly journals 3D Printing of Silk Fibroin for Biomedical Applications

Materials ◽  
2019 ◽  
Vol 12 (3) ◽  
pp. 504 ◽  
Author(s):  
Qiusheng Wang ◽  
Guocong Han ◽  
Shuqin Yan ◽  
Qiang Zhang
Keyword(s):  
3D Printing ◽  
Silk Fibroin ◽  
Three Dimensional ◽  
Chemical Components ◽  
Technological Evolution ◽  
Multiple Processes ◽  
Printing Technique ◽  
Emerging Issues ◽  
Good Biocompatibility ◽  
3D Printing Technique

Three-dimensional (3D) printing is regarded as a critical technological-evolution in material engineering, especially for customized biomedicine. However, a big challenge that hinders the 3D printing technique applied in biomedical field is applicable bioink. Silk fibroin (SF) is used as a biomaterial for decades due to its remarkable high machinability and good biocompatibility and biodegradability, which provides a possible alternate of bioink for 3D printing. In this review, we summarize the requirements, characteristics and processabilities of SF bioink, in particular, focusing on the printing possibilities and capabilities of bioink. Further, the current achievements of cell-loading SF based bioinks were comprehensively viewed from their physical properties, chemical components, and bioactivities as well. Finally, the emerging issues and prospects of SF based bioink for 3D printing are given. This review provides a reference for the programmable and multiple processes and the further improvement of silk-based biomaterials fabrication by 3D printing.

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