Silver nanoparticles coated by green graphene quantum dots for accelerating the healing of MRSA-infected wounds

2020 ◽  
Vol 8 (23) ◽  
pp. 6670-6682 ◽  
Author(s):  
Xianghua Zhong ◽  
Chunyi Tong ◽  
Tiansheng Liu ◽  
Li Li ◽  
Xu Liu ◽  
...  

Bacterial infection, especially multidrug-resistant bacteria-induced infection, threatens human health seriously, which has posed great challenges for clinical therapy.

2015 ◽  
Vol 13 (1) ◽  
Author(s):  
Emerson Danguy Cavassin ◽  
Luiz Francisco Poli de Figueiredo ◽  
José Pinhata Otoch ◽  
Marcelo Martins Seckler ◽  
Roberto Angelo de Oliveira ◽  
...  

2009 ◽  
Vol 26 (4) ◽  
pp. 615-621 ◽  
Author(s):  
Humberto H. Lara ◽  
Nilda V. Ayala-Núñez ◽  
Liliana del Carmen Ixtepan Turrent ◽  
Cristina Rodríguez Padilla

2021 ◽  
Vol 22 (18) ◽  
pp. 9695
Author(s):  
Wen-Shuo Kuo ◽  
Ping-Ching Wu ◽  
Chi-Yao Hung ◽  
Chia-Yuan Chang ◽  
Jiu-Yao Wang ◽  
...  

There is an urgent need for materials that can efficiently generate reactive oxygen species (ROS) and be used in photodynamic therapy (PDT) as two-photon imaging contrast probes. In this study, graphene quantum dots (GQDs) were subjected to amino group functionalization and nitrogen doping (amino-N-GQDs) via annealing and hydrothermal ammonia autoclave treatments. The synthesized dots could serve as a photosensitizer in PDT and generate more ROS than conventional GQDs under 60-s low-energy (fixed output power: 0.07 W·cm−2) excitation exerted by a 670-nm continuous-wave laser. The generated ROS were used to completely eliminate a multidrug-resistant strain of methicillin-resistant Staphylococcus aureus (MRSA), a Gram-positive bacterium. Compared with conventional GQDs, the amino-N-GQDs had superior optical properties, including stronger absorption, higher quantum yield (0.34), stronger luminescence, and high stability under exposure. The high photostability and intrinsic luminescence of amino-N-GQDs contribute to their suitability as contrast probes for use in biomedical imaging, in addition to their bacteria tracking and localization abilities. Herein, the dual-modality amino-N-GQDs in PDT easily eliminated multidrug-resistant bacteria, ultimately revealing their potential for use in future clinical applications.


2020 ◽  
Vol 14 (1) ◽  
pp. 1651-1659
Author(s):  
Raghad R. Alzahrani ◽  
Manal M. Alkhulaifi ◽  
Nouf M. Alenazi ◽  
Nawal M. Almusayeib ◽  
Musarat Amina ◽  
...  

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