Synthesis of fluorescent MOFs: live-cell imaging and sensing of a herbicide

CrystEngComm ◽  
2020 ◽  
Vol 22 (26) ◽  
pp. 4468-4477 ◽  
Author(s):  
Aurobinda Mohanty ◽  
Udai P. Singh ◽  
R. J. Butcher ◽  
Neeladrisingha Das ◽  
Partha Roy
Keyword(s):  
Aromatic Compounds ◽  
Live Cell Imaging ◽  
Cell Imaging ◽  
Metal Organic Frameworks ◽  
Live Cell ◽  
Metal Organic ◽  
Mcf 7 ◽  
Nitro Aromatic

Various metal–organic frameworks of Zn(ii) and Cd(ii) have been synthesized hydrothermally for the detection of herbicide (simazine) as well as nitro-aromatic compounds. Also these MOFs show live-cell imaging for MCF-7 cells.

Encapsulation and Protection of Ultrathin Two-Dimensional Porous Organic Nanosheets within Biocompatible Metal–Organic Frameworks for Live-Cell Imaging

2019 ◽  
Vol 31 (13) ◽  
pp. 4897-4912 ◽  
Author(s):  
Jinqiao Dong ◽  
Zhiwei Qiao ◽  
Yutong Pan ◽  
Shing Bo Peh ◽  
Yi Di Yuan ◽  
...  
Keyword(s):  
Live Cell Imaging ◽  
Cell Imaging ◽  
Metal Organic Frameworks ◽  
Live Cell ◽  
Two Dimensional ◽  
Metal Organic

Synthesis of Fluorescent Nanoscale Salts/Metal–Organic Frameworks for Live-Cell Imaging

2018 ◽  
Vol 18 (5) ◽  
pp. 2804-2813 ◽  
Author(s):  
Udai P. Singh ◽  
Neetu Singh ◽  
Ritu Varshney ◽  
Partha Roy ◽  
Ray J. Butcher
Keyword(s):  
Live Cell Imaging ◽  
Cell Imaging ◽  
Metal Organic Frameworks ◽  
Live Cell ◽  
Metal Organic

Highly fluorescent scandium-tetracarboxylate frameworks: selective detection of nitro-aromatic compounds, sensing mechanism, and their application

2020 ◽  
Vol 49 (48) ◽  
pp. 17737-17744
Author(s):  
Deyi Zhan ◽  
Abdul Saeed ◽  
Zixuan Li ◽  
Chengming Wang ◽  
Zhiwu Yu ◽  
...  
Keyword(s):  
Aromatic Compounds ◽  
Metal Organic Frameworks ◽  
Selective Detection ◽  
Sensing Mechanism ◽  
Metal Organic ◽  
Nitro Aromatic

Recently, exploring new luminescent metal–organic frameworks (LMOFs) to selectively detect nitro-aromatic compounds (NACs) has been a hot topic of research.

Polyhedral borane derivatives: Unique and versatile structural motifs

2012 ◽  
Vol 84 (11) ◽  
pp. 2279-2288 ◽  
Author(s):  
M. Frederick Hawthorne ◽  
Alexei Pushechnikov
Keyword(s):  
Drug Delivery ◽  
Aromatic Compounds ◽  
Live Cell Imaging ◽  
Cell Imaging ◽  
Live Cell ◽  
Molecular Volume ◽  
Structural Motifs ◽  
Modular Assembly ◽  
Drug Delivery Vehicles ◽  
Delivery Vehicles

Compounds with polyhedral borane moieties have demonstrated numerous unique properties for a variety of applications, including nanoelectronics, drug delivery vehicles, and live cell imaging. Polyhedral boranes are good pharmacophore analogs of carbocycles because polyhedral boranes are inherently insensitive to many undesirable enzymatic metabolic transformations typical for a majority of aromatic compounds. The defined shape, low molecular volume, and high 3D symmetry of the surface are useful for the application of the polyhedral borane scaffolds as universal and convenient spacers for the modular assembly approach with a controllable predisposition of peripheral groups.

scholarly journals Pyrene-appended bipyridine hydrazone ligand as a turn-on sensor for Cu2+ and its bioimaging application

RSC Advances ◽  
2020 ◽  
Vol 10 (7) ◽  
pp. 3646-3658 ◽  
Author(s):  
Sayed Muktar Hossain ◽  
Ved Prakash ◽  
Prabhudutta Mamidi ◽  
Soma Chattopadhyay ◽  
Akhilesh Kumar Singh
Keyword(s):  
Live Cell Imaging ◽  
Cell Imaging ◽  
Live Cell ◽  
Hydrazone Ligand ◽  
Turn On ◽  
Metal Organic

A pyrene-based “turn-on” Cu(ii) sensor provides a chemiluminescent Cu6 metal organic macrocycle (MOM) applicable for live cell imaging.

Fluorogenic naked-eye sensing and live-cell imaging of cyanide by a hydrazine-functionalized CAU-10 metal–organic framework

CrystEngComm ◽  
2018 ◽  
Vol 20 (29) ◽  
pp. 4194-4201 ◽  
Author(s):  
Rana Dalapati ◽  
Soutick Nandi ◽  
Helge Reinsch ◽  
Bibhas K. Bhunia ◽  
Biman B. Mandal ◽  
...  
Keyword(s):  
Live Cell Imaging ◽  
Cell Imaging ◽  
Metal Organic Framework ◽  
Living Cells ◽  
Live Cell ◽  
Naked Eye ◽  
Metal Organic ◽  
Organic Framework

A hydrazine-functionalized Al(iii) based metal–organic framework was utilized for the detection of lethal cyanide in water and in living cells.

Ruthenium(II) p-cymene complex of pyridine-2-carboxaldehyde and 2-amino benzothiazole based ligand: A cytoselective and in vitro live cell imaging agent†

2021 ◽  
Author(s):  
Anuja Plavuvalapill Kumar ◽  
Priyankar Paira
Keyword(s):  
Ambient Temperature ◽  
Cancer Cells ◽  
General Formula ◽  
Live Cell Imaging ◽  
Cell Imaging ◽  
Live Cell ◽  
Imaging Agent ◽  
Arene Complexes ◽  
Mcf 7

Five Ru(II)-arene complexes ensuring the general formula [(η6-p-cymene)RuCl(k1L1-L5)(pyridine-2-carboxaldehyde)]Cl were synthesized under ambient temperature which exhibited 8-11 fold of cytoselectivity in two cancer cells (HeLa and MCF-7) with respect to normal...

A quinoline-based probe for effective and selective sensing of aspartic acid in aqueous medium: in vitro and in vivo live cell imaging

2019 ◽  
Vol 6 (11) ◽  
pp. 3237-3244 ◽  
Author(s):  
C. Elamathi ◽  
R. J. Butcher ◽  
A. Mohankumar ◽  
P. Sundararaj ◽  
A. Madankumar ◽  
...  
Keyword(s):  
Aqueous Solution ◽  
Aspartic Acid ◽  
Live Cell Imaging ◽  
Cell Imaging ◽  
Live Cell ◽  
C Elegans ◽  
Highly Sensitive ◽  
Mcf 7

A highly sensitive and selective “on–off–on” chemosensor for aspartic acid in aqueous solution was established. In vitro live cell imaging against MCF 7 cells and in vivo imaging using C. elegans were successfully demonstrated.

scholarly journals Real Microgravity Influences the Cytoskeleton and Focal Adhesions in Human Breast Cancer Cells

2019 ◽  
Vol 20 (13) ◽  
pp. 3156 ◽  
Author(s):  
Mohamed Zakaria Nassef ◽  
Sascha Kopp ◽  
Markus Wehland ◽  
Daniela Melnik ◽  
Jayashree Sahana ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cancer Cells ◽  
Live Cell Imaging ◽  
Breast Cancer Cells ◽  
Cell Imaging ◽  
Live Cell ◽  
Common Mechanism ◽  
Real Microgravity ◽  
Mcf 7 ◽  
E Cadherin

With the increasing number of spaceflights, it is crucial to understand the changes occurring in human cells exposed to real microgravity (r-µg) conditions. We tested the effect of r-µg on MCF-7 breast cancer cells with the objective to investigate cytoskeletal alterations and early changes in the gene expression of factors belonging to the cytoskeleton, extracellular matrix, focal adhesion, and cytokines. In the Technische Experimente unter Schwerelosigkeit (TEXUS) 54 rocket mission, we had the opportunity to conduct our experiment during 6 min of r-µg and focused on cytoskeletal alterations of MCF-7 breast cancer cells expressing the Lifeact-GFP marker protein for the visualization of F-actin as well as the mCherry-tubulin fusion protein using the Fluorescence Microscopy Analysis System (FLUMIAS) for fast live-cell imaging under r-µg. Moreover, in a second mission we investigated changes in RNA transcription and morphology in breast cancer cells exposed to parabolic flight (PF) maneuvers (31st Deutsches Zentrum für Luft- und Raumfahrt (DLR) PF campaign). The MCF-7 cells showed a rearrangement of the F-actin and tubulin with holes, accumulations in the tubulin network, and the appearance of filopodia- and lamellipodia-like structures in the F-actin cytoskeleton shortly after the beginning of the r-µg period. PF maneuvers induced an early up-regulation of KRT8, RDX, TIMP1, CXCL8 mRNAs, and a down-regulation of VCL after the first parabola. E-cadherin protein was significantly reduced and is involved in cell adhesion processes, and plays a significant role in tumorigenesis. Changes in the E-cadherin protein synthesis can lead to tumor progression. Pathway analyses indicate that VCL protein has an activating effect on CDH1. In conclusion, live-cell imaging visualized similar changes as those occurring in thyroid cancer cells in r-µg. This result indicates the presence of a common mechanism of gravity perception and sensation.

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