scholarly journals Spatially offset Raman spectroscopy for biomedical applications

Author(s):  
Fay Nicolson ◽  
Moritz F. Kircher ◽  
Nick Stone ◽  
Pavel Matousek

Recent advances in non-invasive biomedical analysis using SORS are discussed.




Author(s):  
Aleksandr S. Grishkanich ◽  
Aleksandr Zhevlakov ◽  
Egor Mikharev ◽  
Andrey Lunev ◽  
Boris Karas ◽  
...  


Author(s):  
Shuo Zhang ◽  
Frederieke A. M. van der Mee ◽  
Roel J. Erckens ◽  
Carroll A. B. Webers ◽  
Tos T. J. M. Berendschot

AbstractIn this report we present a confocal Raman system to identify the unique spectral features of two proteins, Interleukin-10 and Angiotensin Converting Enzyme. Characteristic Raman spectra were successfully acquired and identified for the first time to our knowledge, showing the potential of Raman spectroscopy as a non-invasive investigation tool for biomedical applications.



2020 ◽  
Vol 8 (1) ◽  
Author(s):  
Klara Retko ◽  
Maša Kavčič ◽  
Lea Legan ◽  
Polonca Ropret ◽  
Bojana Rogelj Škafar ◽  
...  

AbstractIn this study, a painted beehive panel from the collection of the Slovene Ethnographic Museum was examined with respect to its material composition with the aim to reveal the painting technique. Due to the state of degradation due to outdoor weathering (UV irradiation, rainfall, extreme temperature and humidity fluctuations), as well as past conservation interventions, the object represented a complex analytical challenge. We aimed for non-invasive techniques (FTIR in reflection mode, Raman spectroscopy and hyperspectral imaging in the range of 400–2500 nm); however, in order to explore paint layers, cross-sections were also analysed using Raman spectroscopy. FTIR spectroscopy in transmission mode and gas chromatography coupled to mass spectrometry were also used on sample fragments. Various original materials were identified such as pigments and binders. The surface coating applied during conservation interventions was also characterised. Additionally, organic compounds were found (oxalate, carboxylate), representing transformation products. The potential use of Prussian blue as a background paint layer is discussed.



2021 ◽  
Vol 50 (6) ◽  
pp. 4141-4161
Author(s):  
Thomas Jet ◽  
Guillaume Gines ◽  
Yannick Rondelez ◽  
Valérie Taly

Multiplex miRNA detection is a promising way to non-invasive diagnostics. In this review, we discuss the recent advances to the multiplexing of miRNA quantification.





Author(s):  
Huai-Qing Chen ◽  
Wan Yang ◽  
Hua Zuo ◽  
Hua-Wei He ◽  
Ye-Jing Wang


Author(s):  
Subhasish Sahoo ◽  
Pooja Ghosh ◽  
Supratim Banerjee ◽  
Priyadarsi De


2021 ◽  
Vol 11 (3) ◽  
pp. 1235
Author(s):  
Su Min Yun ◽  
Moohyun Kim ◽  
Yong Won Kwon ◽  
Hyobeom Kim ◽  
Mi Jung Kim ◽  
...  

The development of wearable sensors is aimed at enabling continuous real-time health monitoring, which leads to timely and precise diagnosis anytime and anywhere. Unlike conventional wearable sensors that are somewhat bulky, rigid, and planar, research for next-generation wearable sensors has been focused on establishing fully-wearable systems. To attain such excellent wearability while providing accurate and reliable measurements, fabrication strategies should include (1) proper choices of materials and structural designs, (2) constructing efficient wireless power and data transmission systems, and (3) developing highly-integrated sensing systems. Herein, we discuss recent advances in wearable devices for non-invasive sensing, with focuses on materials design, nano/microfabrication, sensors, wireless technologies, and the integration of those.



Author(s):  
Jijo Lukose ◽  
Sanoop Pavithran M. ◽  
Mithun N. ◽  
Ajaya Kumar Barik ◽  
Keerthilatha M. Pai ◽  
...  

AbstractHuman saliva can be treated as a pool of biological markers able to reflect on the state of personal health. Recent years have witnessed an increase in the use of optical devices for the analysis of body fluids. Several groups have carried out studies investigating the potential of saliva as a non-invasive and reliable clinical specimen for use in medical diagnostics. This brief review aims to highlight the optical technologies, mainly surface plasmon resonance (SPR), Raman, and Fourier transform infrared (FTIR) spectroscopy, which are being used for the probing of saliva for diverse biomedical applications. Advances in bio photonics offer the promise of unambiguous, objective and fast detection of abnormal health conditions and viral infections (such as COVID-19) from the analysis of saliva.



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