scholarly journals Microwave-assisted simple synthesis of 2-anilinopyrimidines by the reaction of 2-chloro-4,6-dimethylpyrimidine with aniline derivatives

RSC Advances ◽  
2020 ◽  
Vol 10 (21) ◽  
pp. 12249-12254 ◽  
Author(s):  
Cristina Campestre ◽  
György Keglevich ◽  
János Kóti ◽  
Luca Scotti ◽  
Carla Gasbarri ◽  
...  
Keyword(s):  
Microwave Heating ◽  
Simple Synthesis ◽  
New Method ◽  
One Pot ◽  
Active Compounds ◽  
Microwave Assisted ◽  
Aniline Derivatives ◽  
Green Approach ◽  
High Yields

A rapid, one pot, green approach by microwave heating in ethanol provides a new method to obtain active and new potentially active compounds in high yields.

scholarly journals Microwave-assisted efficient one-pot synthesis of N 2-(tetrazol-5-yl)-6-aryl/heteroaryl-5,6-dihydro-1,3,5-triazine-2,4-diamines

2020 ◽  
Vol 16 ◽  
pp. 1706-1712
Author(s):  
Moustafa Sherief Moustafa ◽  
Ramadan Ahmed Mekheimer ◽  
Saleh Mohammed Al-Mousawi ◽  
Mohamed Abd-Elmonem ◽  
Hesham El-Zorba ◽  
...  
Keyword(s):  
Microwave Heating ◽  
Aromatic Aldehydes ◽  
One Pot ◽  
X Ray ◽  
X Ray Crystallography ◽  
Microwave Assisted ◽  
One Pot Synthesis ◽  
High Yields

An efficient one-pot synthesis of N 2-(tetrazol-5-yl)-6-aryl/heteroaryl-1,3,5-triazine-2,4-diamine derivatives was developed by reacting 5-amino-1,2,3,4-tetrazole with aromatic aldehydes and cyanamide in pyridine under controlled microwave heating with high yields. X-ray crystallography confirmed the structure of the obtained products.

scholarly journals Microwave-assisted efficient one-pot synthesis of N 2-(tetrazol-5-yl)-6-aryl/heteroaryl-2,3-dihydro-1,3,5-triazine-2,4-diamines

2020 ◽  
Author(s):  
Moustafa Moustafa ◽  
Ramadan Mekheimer ◽  
Saleh Al-Mousawi ◽  
Mohamed Abd-Elmonem ◽  
Hesham El-Zorba ◽  
...  
Keyword(s):  
Microwave Heating ◽  
Aromatic Aldehydes ◽  
One Pot ◽  
X Ray ◽  
X Ray Crystallography ◽  
Microwave Assisted ◽  
One Pot Synthesis ◽  
High Yields

An efficient one-pot synthesis of N 2-(tetrazol-5-yl)-6-aryl/heteroaryl-1,3,5-triazine-2,4-diamine derivatives was developed by reacting 5-amino-1,2,3,4-tetrazole with aromatic aldehydes and cyanamide in pyridine under controlled microwave heating with high yields. X-ray crystallography confirmed the structure of obtained products.  

A highly efficient and green approach for the synthesis of pyrimido[4,5-b]quinolines using N,N-diethyl-N-sulfoethanaminium chloride

2021 ◽  
Vol 76 (2) ◽  
pp. 85-90
Author(s):  
Abdolkarim Zare ◽  
Manije Dianat
Keyword(s):  
Reaction Times ◽  
Solvent Free ◽  
One Pot ◽  
Catalyst Amount ◽  
Green Protocol ◽  
Highly Efficient ◽  
Green Approach ◽  
Solvent Free Conditions ◽  
The One ◽  
High Yields

Abstract A highly efficient and green protocol for the synthesis of pyrimido[4,5-b]quinolines has been described. The one-pot multicomponent reaction of dimedone with arylaldehydes and 6-amino-1,3-dimethyluracil in the presence of N,N-diethyl-N-sulfoethanaminium chloride ([Et3N–SO3H][Cl]) as an ionic liquid (IL) catalyst under solvent-free conditions afforded the mentioned compounds in high yields and short reaction times. Our protocol is superior to many of the reported protocols in terms of two or more of these factors: the reaction times, yields, conditions (solvent-free versus usage of organic solvents), temperature and catalyst amount.

Microwave-Assisted, One-Pot Reaction of Pyridines, α-Bromoketones and Ammonium Acetate: An Efficient and Simple Synthesis of Imidazo[1,2-a]-pyridines

Synlett ◽  
2010 ◽  
Vol 2010 (11) ◽  
pp. 1606-1608 ◽  
Author(s):  
Mehdi Adib ◽  
Hamid Bijanzadeh ◽  
Ali Mohamadi ◽  
Ehsan Sheikhi ◽  
Samira Ansari
Keyword(s):  
Ammonium Acetate ◽  
Simple Synthesis ◽  
One Pot ◽  
Microwave Assisted

A Green Approach for the Synthesis of Novel 7,11-Dihydro-6H-chromeno[3,4-e]isoxazolo[5,4-b]pyridin-6-one Derivatives Using Acidic Ionic Liquid [C4mim][HSO4]

2016 ◽  
Vol 69 (9) ◽  
pp. 1049 ◽  
Author(s):  
Sudesh Kumari ◽  
M. Rajeswari ◽  
Jitender M. Khurana
Keyword(s):  
Ionic Liquid ◽  
Crystal Packing ◽  
Aromatic Aldehydes ◽  
Green Solvent ◽  
One Pot ◽  
X Ray ◽  
Acidic Ionic Liquid ◽  
Green Approach ◽  
Wide Range ◽  
High Yields

A multicomponent reaction capable of affording a wide range of novel 7,11-dihydro-6H-chromeno[3,4-e]isoxazolo[5,4-b]pyridin-6-one derivatives via one-pot three-component condensation of 4-hydroxycoumarin, aromatic aldehydes, and 5-amino-3-methylisoxazole in ionic liquid 1-butyl-3-methylimidazolium hydrogen sulfate ([C4mim][HSO4]) is reported. Structures have been confirmed by spectral and X-ray studies. Crystal packing of 4b has also been reported. Green solvent, short reaction time, easy workup, and high yields are the salient features of the present protocol.

ChemInform Abstract: Microwave-Assisted, One-Pot Reaction of Pyridines, α-Bromoketones and Ammonium Acetate: An Efficient and Simple Synthesis of Imidazo[1,2-a]pyridines.

ChemInform ◽  
2010 ◽  
Vol 41 (46) ◽  
pp. no-no
Author(s):  
Mehdi Adib ◽  
Ali Mohamadi ◽  
Ehsan Sheikhi ◽  
Samira Ansari ◽  
Hamid Reza Bijanzadeh
Keyword(s):  
Ammonium Acetate ◽  
Simple Synthesis ◽  
One Pot ◽  
Microwave Assisted

scholarly journals One-pot, three-component synthesis of pyrrolo[2,3-d]pyrimidine derivatives

2018 ◽  
Vol 62 (1) ◽  
Author(s):  
Jabbar Khalafy ◽  
Ramin Javahershenas
Keyword(s):  
Simple Procedure ◽  
Reaction Times ◽  
Pyrimidine Derivatives ◽  
Reaction Conditions ◽  
One Pot ◽  
General Applicability ◽  
Green Approach ◽  
Three Component Reaction ◽  
High Yields ◽  
Work Up

<p>A green approach for the synthesis of polyfunctionalized pyrrolo[2,3-<em>d</em>]pyrimidine derivatives was successfully achieved by a one-pot, three-component reaction of arylglyoxals, 6-amino-1,3-dimethyluracil and barbituric acid derivatives in the presence of tetra-<em>n</em>-butylammonium bromide (TBAB) (5 mol%) as the catalyst in ethanol at 50 °C. This protocol has many advantages such as high yields (73-95%), green and simple procedure, short reaction times, easy work-up, mild reaction conditions and general applicability.</p>

Microwave-assisted expeditious and efficient synthesis of novel quinolin-4-ylmethoxychromen-2- and -4-ones catalyzed by YbCl3 under a solvent free one-pot three component domino reaction and their antimicrobial activity

RSC Advances ◽  
2015 ◽  
Vol 5 (113) ◽  
pp. 93067-93080 ◽  
Author(s):  
Sumit Kumar ◽  
Alok Patel ◽  
Naseem Ahmed
Keyword(s):  
Antimicrobial Activity ◽  
Solvent Free ◽  
Domino Reaction ◽  
Efficient Synthesis ◽  
One Pot ◽  
Microwave Assisted ◽  
High Yields

MW assisted multicomponent A3 synthesis was developed for the synthesis of quinolin-4-ylmethoxychromen-2- and -4-ones in high yields with YbCl3 and reused efficiently for four times.

Microwave-Assisted Efficient synthesis of Dihydro Pyrimidines: Improved High Yielding Protocol for the Biginelli Reaction

2000 ◽  
Vol 2000 (7) ◽  
pp. 354-355 ◽  
Author(s):  
J.S. Yadav ◽  
B.V. Subba Reddy ◽  
E. Jagan Reddy ◽  
T. Ramalingam
Keyword(s):  
Acetic Acid ◽  
Microwave Irradiation ◽  
Biginelli Reaction ◽  
Acid Catalysts ◽  
Efficient Synthesis ◽  
One Pot ◽  
Amberlyst 15 ◽  
Microwave Assisted ◽  
Cyclocondensation Reaction ◽  
High Yields

Dihydropyrimidines were synthesised in high yields by one-pot cyclocondensation reaction of aldehydes, aceto-acetates and urea using various acid catalysts like Amberlyst-15, Nafion-H, KSF clay and dry acetic acid under microwave irradiation.

scholarly journals Microwave-Assisted Three-Component “Catalyst and Solvent-Free” Green Protocol: A Highly Efficient and Clean One-Pot Synthesis of Tetrahydrobenzo[b]pyrans

2014 ◽  
Vol 2014 ◽  
pp. 1-8 ◽  
Author(s):  
Sougata Santra ◽  
Matiur Rahman ◽  
Anupam Roy ◽  
Adinath Majee ◽  
Alakananda Hajra
Keyword(s):  
Knoevenagel Condensation ◽  
One Pot ◽  
Green Protocol ◽  
Microwave Assisted ◽  
Highly Efficient ◽  
One Pot Synthesis ◽  
Purification Technique ◽  
The One ◽  
High Yields ◽  
Operational Simplicity

A green and highly efficient method has been developed for the one-pot synthesis of tetrahydrobenzo[b]pyrans via a three-component condensation of aldehydes, 1,3-cyclic diketones, and malononitrile under MW irradiation without using any catalyst and solvent. This transformation presumably occurs by a sequential Knoevenagel condensation, Michael addition, and intramolecular cyclization. Operational simplicity, solvent and catalyst-free conditions, the compatibility with various functional groups, nonchromatographic purification technique, and high yields are the notable advantages of this procedure.

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