Mesenchymal stem cell-derived microvesicles mediate BMP2 gene delivery and enhance bone regeneration

2020 ◽  
Vol 8 (30) ◽  
pp. 6378-6389 ◽  
Author(s):  
Zhuo Liang ◽  
Yue Luo ◽  
Yonggang Lv
Keyword(s):  
Stem Cell ◽  
Gene Delivery ◽  
Mesenchymal Stem Cell ◽  
Bone Regeneration ◽  
Self Assembly ◽  
Bone Repair ◽  
Layer By Layer

Microvesicles–polyethyleneimine/pDNA formed via layer-by-layer self-assembly increase the delivery of hBMP2 plasmids and enhance bone repair.

scholarly journals Trb3 controls mesenchymal stem cell lineage fate and enhances bone regeneration by scaffold-mediated local gene delivery

Biomaterials ◽  
2021 ◽  
Vol 264 ◽  
pp. 120445
Author(s):  
Jiabing Fan ◽  
Chung-Sung Lee ◽  
Soyon Kim ◽  
Xiao Zhang ◽  
Joan Pi-Anfruns ◽  
...  
Keyword(s):  
Stem Cell ◽  
Gene Delivery ◽  
Mesenchymal Stem Cell ◽  
Bone Regeneration ◽  
Cell Lineage ◽  
Stem Cell Lineage

A cancellous bone matrix system with specific mineralisation degrees for mesenchymal stem cell differentiation and bone regeneration

2019 ◽  
Vol 7 (6) ◽  
pp. 2452-2467 ◽  
Author(s):  
Shijie Liu ◽  
Yiyun Wang ◽  
Jian Wang ◽  
Pengcheng Qiu ◽  
Shengyu Wang ◽  
...  
Keyword(s):  
Stem Cell ◽  
Cell Differentiation ◽  
Mesenchymal Stem Cell ◽  
Bone Regeneration ◽  
Cancellous Bone ◽  
Bone Matrix ◽  
Stem Cell Differentiation ◽  
Matrix System ◽  
Mesenchymal Stem Cell Differentiation ◽  
Regenerative Therapies

Bone regenerative therapies have been explored using various biomaterial systems.

scholarly journals IL-12p40 impairs mesenchymal stem cell-mediated bone regeneration via CD4+ T cells

2016 ◽  
Vol 23 (12) ◽  
pp. 1941-1951 ◽  
Author(s):  
Jiajia Xu ◽  
Yiyun Wang ◽  
Jing Li ◽  
Xudong Zhang ◽  
Yiyun Geng ◽  
...  
Keyword(s):  
T Cells ◽  
Stem Cell ◽  
Mesenchymal Stem Cell ◽  
Bone Regeneration ◽  
Cd4 T Cells

scholarly journals Umbilical cord and bone marrow mesenchymal stem cell seeding on macroporous calcium phosphate for bone regeneration in rat cranial defects

Biomaterials ◽  
2013 ◽  
Vol 34 (38) ◽  
pp. 9917-9925 ◽  
Author(s):  
Wenchuan Chen ◽  
Jun Liu ◽  
Navid Manuchehrabadi ◽  
Michael D. Weir ◽  
Zhimin Zhu ◽  
...  
Keyword(s):  
Bone Marrow ◽  
Stem Cell ◽  
Calcium Phosphate ◽  
Mesenchymal Stem Cell ◽  
Bone Regeneration ◽  
Umbilical Cord ◽  
Cell Seeding

scholarly journals Mesenchymal Stem Cell-mediated Gene Delivery of Bone Morphogenetic Protein-2 in an Articular Fracture Model

2007 ◽  
Vol 15 (8) ◽  
pp. 1543-1550 ◽  
Author(s):  
Terri Zachos ◽  
Alisha Diggs ◽  
Steven Weisbrode ◽  
Jeffrey Bartlett ◽  
Alicia Bertone
Keyword(s):  
Stem Cell ◽  
Gene Delivery ◽  
Mesenchymal Stem Cell ◽  
Bone Morphogenetic Protein ◽  
Fracture Model ◽  
Bone Morphogenetic Protein 2 ◽  
Articular Fracture ◽  
Morphogenetic Protein
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