Ubiquinone-BODIPY nanoparticles for tumor redox-responsive fluorescence imaging and photodynamic activity

2021 ◽  
Author(s):  
Byunghee Hwang ◽  
Tae-Il Kim ◽  
Hyunjin Kim ◽  
Sungjin Jeon ◽  
Yongdoo Choi ◽  
...  
Keyword(s):  
Fluorescence Imaging ◽  
Selective Activation ◽  
Turn On ◽  
Intracellular Environment ◽  
Redox Responsive ◽  
Photodynamic Activity

A ubiquinone-BODIPY photosensitizer self-assembles into nanoparticles (PS-Q-NPs) and undergoes selective activation within the highly reductive intracellular environment of tumors, resulting in “turn-on” fluorescence and photosensitizing activities.

Redox-responsive FRET-based polymer dot with BODIPY for fluorescence imaging-guided chemotherapy of tumor

2018 ◽  
Vol 132 ◽  
pp. 200-210 ◽  
Author(s):  
Young Kwang Kim ◽  
Jung Eun Lee ◽  
Benny Ryplida ◽  
Cheong A Choi ◽  
Zihnil Adha Islamy Mazrad ◽  
...  
Keyword(s):  
Fluorescence Imaging ◽  
Redox Responsive

scholarly journals Cu-Based Turn-on Fluorescent Sensors for Cu-rich Amyloid β Aggregates

2021 ◽  
Author(s):  
Yiran Huang ◽  
Liang Sun ◽  
Liviu M. Mirica
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Fluorescence Imaging ◽  
Protein Misfolding ◽  
Picolinic Acid ◽  
Amyloid Β ◽  
Fluorescent Sensors ◽  
Aβ Oligomers ◽  
Turn On ◽  
Aβ Aggregation

<div>Protein misfolding and metal dishomeostasis are two key</div><div>pathological factors of Alzheimer’s disease. Previous studies have showed that Cu‐mediated Aβ aggregation pathways lead to formation of neurotoxic Aβ oligomers. Herein, we reported a series of picolinic acid‐based Cu‐activatable sensors, which can be used for the fluorescence imaging of Cu‐rich Aβ aggregates.</div>

A redox-responsive folate–fluorophore conjugate as a new target-cell-specific imaging probe

2018 ◽  
Vol 6 (17) ◽  
pp. 2524-2527 ◽  
Author(s):  
Jisu Kim ◽  
Hyunjin Kim ◽  
Yongdoo Choi
Keyword(s):  
Fluorescence Imaging ◽  
Target Cell ◽  
Imaging Probe ◽  
Redox Responsive

Here, we have developed a redox-responsive folate–fluorophore conjugate with a disulfide linker for the target-specific activatable fluorescence imaging of cancers.

Disulfide bond-based self-crosslinked carbon-dots for turn-on fluorescence imaging of GSH in living cells

The Analyst ◽  
2020 ◽  
Vol 145 (8) ◽  
pp. 2982-2987 ◽  
Author(s):  
Jia Li ◽  
Yuhui Wang ◽  
Shan Sun ◽  
A-Man Lv ◽  
Kai Jiang ◽  
...  
Keyword(s):  
Fluorescence Imaging ◽  
Disulfide Bond ◽  
Carbon Dots ◽  
Living Cells ◽  
Turn On

A self-quenched nanoprobe built on a disulfide bond-based crosslink of carbon-dots has been constructed for intracellular GSH sensing.

scholarly journals A glutathione responsive pyrrolopyrrolidone nanotheranostic agent for turn-on fluorescence imaging guided photothermal/photodynamic cancer therapy

2019 ◽  
Vol 3 (10) ◽  
pp. 2143-2150 ◽  
Author(s):  
Jianhua Zou ◽  
Lei Xue ◽  
Nan Yang ◽  
Yanfang Ren ◽  
Zhe Fan ◽  
...  
Keyword(s):  
Cancer Therapy ◽  
Fluorescence Imaging ◽  
Therapeutic Efficacy ◽  
Turn On ◽  
Photodynamic Cancer Therapy

Herein, GSH responsive pyrrolopyrrolidone derivatives with enhanced photodynamic/photothermal therapeutic efficacy were designed, which can be used as colorimetric probes.

A fluorescent probe for the discrimination between Cys and GSH

2015 ◽  
Vol 7 (24) ◽  
pp. 10371-10375 ◽  
Author(s):  
Lun Song ◽  
Qian Sun ◽  
Nan Wang ◽  
Zhaoyang Chen ◽  
Weibing Zhang ◽  
...  
Keyword(s):  
Fluorescent Probe ◽  
Fluorescence Imaging ◽  
Turn On ◽  
Spectral Channels

A turn-on fluorescent probe was designed and synthesized for discriminating between Cys and GSH from different spectral channels. The probe has potential in fluorescence imaging of cellular Cys.

scholarly journals Redox-responsive branched-bottlebrush polymers for in vivo MRI and fluorescence imaging

2014 ◽  
Vol 5 (1) ◽  
Author(s):  
Molly A. Sowers ◽  
Jessica R. McCombs ◽  
Ying Wang ◽  
Joseph T. Paletta ◽  
Stephen W. Morton ◽  
...  
Keyword(s):  
Fluorescence Imaging ◽  
Redox Responsive

Cancer Selective Turn-On Fluorescence Imaging Using a Biopolymeric Nanocarrier

2019 ◽  
Vol 20 (2) ◽  
pp. 1068-1076 ◽  
Author(s):  
Yoon Jeong ◽  
Garam Kim ◽  
Soohyun Jeong ◽  
Byungchul Lee ◽  
Sangeun Kim ◽  
...  
Keyword(s):  
Fluorescence Imaging ◽  
Turn On

scholarly journals Binding-induced, turn-on fluorescence of the EGFR/ERBB kinase inhibitor, lapatinib

2015 ◽  
Vol 13 (17) ◽  
pp. 5006-5011 ◽  
Author(s):  
James N. Wilson ◽  
Wenjun Liu ◽  
Adrienne S. Brown ◽  
Ralf Landgraf
Keyword(s):  
Fluorescence Imaging ◽  
Cellular Uptake ◽  
Kinase Inhibitor ◽  
Photophysical Properties ◽  
Turn On

The photophysical properties, fluorescence imaging, cellular uptake and distribution of lapatinib, an EGFR/ERBB inhibitor are reported.

Sign in / Sign up

Export Citation Format

Share Document