Redox-responsive FRET-based polymer dot with BODIPY for fluorescence imaging-guided chemotherapy of tumor

2018 ◽  
Vol 132 ◽  
pp. 200-210 ◽  
Author(s):  
Young Kwang Kim ◽  
Jung Eun Lee ◽  
Benny Ryplida ◽  
Cheong A Choi ◽  
Zihnil Adha Islamy Mazrad ◽  
...  
Keyword(s):  
Fluorescence Imaging ◽  
Redox Responsive

Ubiquinone-BODIPY nanoparticles for tumor redox-responsive fluorescence imaging and photodynamic activity

2021 ◽  
Author(s):  
Byunghee Hwang ◽  
Tae-Il Kim ◽  
Hyunjin Kim ◽  
Sungjin Jeon ◽  
Yongdoo Choi ◽  
...  
Keyword(s):  
Fluorescence Imaging ◽  
Selective Activation ◽  
Turn On ◽  
Intracellular Environment ◽  
Redox Responsive ◽  
Photodynamic Activity

A ubiquinone-BODIPY photosensitizer self-assembles into nanoparticles (PS-Q-NPs) and undergoes selective activation within the highly reductive intracellular environment of tumors, resulting in “turn-on” fluorescence and photosensitizing activities.

A redox-responsive folate–fluorophore conjugate as a new target-cell-specific imaging probe

2018 ◽  
Vol 6 (17) ◽  
pp. 2524-2527 ◽  
Author(s):  
Jisu Kim ◽  
Hyunjin Kim ◽  
Yongdoo Choi
Keyword(s):  
Fluorescence Imaging ◽  
Target Cell ◽  
Imaging Probe ◽  
Redox Responsive

Here, we have developed a redox-responsive folate–fluorophore conjugate with a disulfide linker for the target-specific activatable fluorescence imaging of cancers.

scholarly journals Redox-responsive branched-bottlebrush polymers for in vivo MRI and fluorescence imaging

2014 ◽  
Vol 5 (1) ◽  
Author(s):  
Molly A. Sowers ◽  
Jessica R. McCombs ◽  
Ying Wang ◽  
Joseph T. Paletta ◽  
Stephen W. Morton ◽  
...  
Keyword(s):  
Fluorescence Imaging ◽  
Redox Responsive

A redox-responsive mesoporous silica based nanoplatform for in vitro tumor-specific fluorescence imaging and enhanced photodynamic therapy

2018 ◽  
Vol 6 (1) ◽  
pp. 96-100 ◽  
Author(s):  
Fan Yuan ◽  
Jiang-Lan Li ◽  
Han Cheng ◽  
Xuan Zeng ◽  
Xian-Zheng Zhang
Keyword(s):  
Photodynamic Therapy ◽  
Tumor Microenvironment ◽  
Mesoporous Silica ◽  
Fluorescence Imaging ◽  
Silica Nanoparticle ◽  
Mesoporous Silica Nanoparticle ◽  
Specific Fluorescence ◽  
Redox Responsive ◽  
Multifunctional Peptides

A mesoporous silica nanoparticle-based redox-responsive platform modified with multifunctional peptides was successfully developed for in vitro tumor microenvironment-enhanced photodynamic therapy.

A redox-responsive theranostic agent for target-specific fluorescence imaging and photodynamic therapy of EGFR-overexpressing triple-negative breast cancers

2016 ◽  
Vol 4 (42) ◽  
pp. 6787-6790 ◽  
Author(s):  
Jisu Kim ◽  
Youngjae Won ◽  
Sung-Ho Goh ◽  
Yongdoo Choi
Keyword(s):  
Photodynamic Therapy ◽  
Fluorescence Imaging ◽  
Target Cell ◽  
Triple Negative ◽  
Breast Cancers ◽  
Specific Fluorescence ◽  
Theranostic Agent ◽  
Redox Responsive

A redox-responsive specific theranostic agent for target-cell-specific activatable fluorescence imaging and photodynamic therapy of triple-negative breast cancers.

Redox-Responsive Nanoparticles with Aggregation-Induced Emission (AIE) Characteristic for Fluorescence Imaging

2014 ◽  
Vol 14 (8) ◽  
pp. 1059-1066 ◽  
Author(s):  
Weiren Cheng ◽  
Guan Wang ◽  
Xiaoyong Pan ◽  
Yong Zhang ◽  
Ben Zhong Tang ◽  
...  
Keyword(s):  
Fluorescence Imaging ◽  
Aggregation Induced Emission ◽  
Redox Responsive

The influence of confocal microscope design on imaging performance

1993 ◽  
Vol 51 ◽  
pp. 144-145
Author(s):  
C J R Sheppard
Keyword(s):  
Image Quality ◽  
Fluorescence Imaging ◽  
Confocal Microscope ◽  
Industrial Applications ◽  
Three Dimensions ◽  
Design Parameters ◽  
Weak Signals ◽  
Size And Shape ◽  
Imaging Performance ◽  
Fundamental Limitation

The confocal microscope is now widely used in both biomedical and industrial applications for imaging, in three dimensions, objects with appreciable depth. There are now a range of different microscopes on the market, which have adopted a variety of different designs. The aim of this paper is to explore the effects on imaging performance of design parameters including the method of scanning, the type of detector, and the size and shape of the confocal aperture.It is becoming apparent that there is no such thing as an ideal confocal microscope: all systems have limitations and the best compromise depends on what the microscope is used for and how it is used. The most important compromise at present is between image quality and speed of scanning, which is particularly apparent when imaging with very weak signals. If great speed is not of importance, then the fundamental limitation for fluorescence imaging is the detection of sufficient numbers of photons before the fluorochrome bleaches.

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