Predicting Differential Ion Mobility Behaviour in silico using Machine Learning

Differential Mobility ◽

Mobility Behaviour ◽

Separation Conditions

Although there has been a surge in popularity of differential mobility spectrometry (DMS) within analytical workflows, determining separation conditions within the DMS parameter space still requires manual optimization. A means...

Time-of-flight ion mobility spectrometry and differential mobility spectrometry: A comparative study of their efficiency in the analysis of halogenated compounds

Talanta ◽

10.1016/j.talanta.2006.08.017 ◽

2007 ◽

Vol 71 (4) ◽

pp. 1804-1812 ◽

Cited By ~ 22

Author(s):

H. Borsdorf ◽

E.G. Nazarov ◽

R.A. Miller

Keyword(s):

Comparative Study ◽

Ion Mobility Spectrometry ◽

Ion Mobility ◽

Time Of Flight ◽

Halogenated Compounds ◽

Hyphenated differential mobility spectrometry for rapid separation and detection

Reviews in Analytical Chemistry ◽

10.1515/revac-2015-0017 ◽

2016 ◽

Vol 35 (1) ◽

pp. 29-40

Author(s):

Liu Yang ◽

Qiang Han ◽

Shuya Cao ◽

Junchao Yang ◽

Jiang Zhao ◽

...

Keyword(s):

Ion Mobility ◽

Chemical Warfare Agents ◽

Chemical Warfare ◽

Real Field ◽

Asymmetric Waveform ◽

Differential Mobility ◽

Rapid Separation ◽

Volatile Organic ◽

Warfare Agents

AbstractThis paper reviews hyphenated differential mobility spectrometry (DMS) technology. DMS is a type of ion mobility spectrometry (IMS) also called high-field asymmetric waveform IMS. It is widely used in the detection of chemical warfare agents, explosives, drugs, and volatile organic compounds. Stand-alone DMS analysis of complex mixtures in real-field applications is challenging. Hyphenated DMS can improve resolution for rapid separation and detection. This review focuses on hyphenated DMS, including gas chromatography-DMS, DMS-mass spectrometry (MS), DMS-IMS, IMS-DMS, and DMS-DMS, as well as their associated principles, applications, and research procedures. Key problems in hyphenated DMS are considered.

Clustering and Nonclustering Modifier Mixtures in Differential Mobility Spectrometry for Multidimensional Liquid Chromatography Ion Mobility–Mass Spectrometry Analysis

Analytical Chemistry ◽

10.1021/acs.analchem.0c04889 ◽

2021 ◽

Vol 93 (17) ◽

pp. 6638-6645

Author(s):

David Ruskic ◽

Frank Klont ◽

Gérard Hopfgartner

Keyword(s):

Mass Spectrometry ◽

Liquid Chromatography ◽

Ion Mobility ◽

Mass Spectrometry Analysis ◽

Ion Mobility Mass Spectrometry ◽

Differential Mobility ◽

Spectrometry Analysis

Differential Mobility Spectrometry of Isomeric Protonated Dipeptides: Modifier and Field Effects on Ion Mobility and Stability

Analytical Chemistry ◽

10.1021/ac200100s ◽

2011 ◽

Vol 83 (9) ◽

pp. 3470-3476 ◽

Cited By ~ 42

Author(s):

Voislav Blagojevic ◽

Alexander Chramow ◽

Bradley B. Schneider ◽

Thomas R. Covey ◽

Diethard K. Bohme

Keyword(s):

Ion Mobility ◽

Differential Mobility ◽

Field Effects

Dissociation of Proton Bound Ketone Dimers in Asymmetric Electric Fields with Differential Mobility Spectrometry and in Uniform Electric Fields with Linear Ion Mobility Spectrometry

The Journal of Physical Chemistry A ◽

10.1021/jp401640t ◽

2013 ◽

Vol 117 (30) ◽

pp. 6389-6401 ◽

Cited By ~ 15

Author(s):

Xinxia An ◽

Gary A. Eiceman ◽

Riikka-Marjaana Räsänen ◽

Jaime E. Rodriguez ◽

John A. Stone

Keyword(s):

Electric Fields ◽

Ion Mobility Spectrometry ◽

Ion Mobility ◽

Review of applications of high-field asymmetric waveform ion mobility spectrometry (FAIMS) and differential mobility spectrometry (DMS)

The Analyst ◽

10.1039/b706039d ◽

2007 ◽

Vol 132 (9) ◽

pp. 842 ◽

Cited By ~ 224

Author(s):

Beata M. Kolakowski ◽

Zoltán Mester

Keyword(s):

Ion Mobility Spectrometry ◽

Ion Mobility ◽

High Field ◽

Asymmetric Waveform ◽

Thermal Desorption Solid-Phase Microextraction Inlet for Differential Mobility Spectrometry

Applied Spectroscopy ◽

10.1366/0003702054280630 ◽

2005 ◽

Vol 59 (6) ◽

pp. 754-762 ◽

Cited By ~ 13

Author(s):

Matthew R. Rainsberg ◽

Peter de B. Harrington

Keyword(s):

Environmental Monitoring ◽

Thermal Desorption ◽

Ion Mobility ◽

Solid Phase Microextraction ◽

Solid Phase ◽

Detection Limits ◽

Differential Mobility ◽

Benzene Toluene ◽

Detection Capabilities

A splitless thermal desorber unit that interfaces a differential mobility spectrometry (DMS) sensor has been devised. This device was characterized by the detection of benzene, toluene, and xylene (BTX) in water. The detection of BTX in water is important for environmental monitoring, and ion mobility measurements are traditionally difficult for hydrocarbons in water because water competes for charge and quenches the hydrocarbon signals. This paper reports the use of a DMS with a photoionization source that is directly coupled to a solid-phase microextraction (SPME) desorber. The separation and detection capabilities of the DMS were demonstrated using BTX components. Detection limits for benzene, toluene, and m-xylene were 75, 50, and 5 μg mL−1, respectively.

Determining molecular properties with differential mobility spectrometry and machine learning

Nature Communications ◽

10.1038/s41467-018-07616-w ◽

2018 ◽

Vol 9 (1) ◽

Cited By ~ 10

Author(s):

Stephen W. C. Walker ◽

Ahdia Anwar ◽

Jarrod M. Psutka ◽

Jeff Crouse ◽

Chang Liu ◽

...

Keyword(s):

Machine Learning ◽

Molecular Properties ◽

Tandem differential mobility spectrometry with ion dissociation in air at ambient pressure and temperature

The Analyst ◽

10.1039/c4an02159b ◽

2015 ◽

Vol 140 (9) ◽

pp. 2995-3002 ◽

Cited By ~ 13

Author(s):

M. R. Menlyadiev ◽

A. Tarassov ◽

A. M. Kielnecker ◽

G. A. Eiceman

Keyword(s):

Ion Mobility ◽

Ambient Pressure ◽

Ambient Conditions ◽

Differential Mobility ◽

Ion Dissociation ◽

Proton Bound Dimer

Proton-bound dimer ions were dissociated in tandem ultraFAIMS/DMS at or near ambient conditions, opening new possibilities for selective ion mobility measurements with DMS.