Tandem differential mobility spectrometry with ion dissociation in air at ambient pressure and temperature

Proton-bound dimer ions were dissociated in tandem ultraFAIMS/DMS at or near ambient conditions, opening new possibilities for selective ion mobility measurements with DMS.

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Predicting Differential Ion Mobility Behaviour in silico using Machine Learning

The Analyst ◽

10.1039/d1an00557j ◽

2021 ◽

Author(s):

Christian Ieritano ◽

J. Larry Campbell ◽

Scott Hopkins

Keyword(s):

Machine Learning ◽

Parameter Space ◽

Ion Mobility ◽

In Silico ◽

Differential Mobility Spectrometry ◽

Differential Mobility ◽

Mobility Behaviour ◽

Separation Conditions

Although there has been a surge in popularity of differential mobility spectrometry (DMS) within analytical workflows, determining separation conditions within the DMS parameter space still requires manual optimization. A means...

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Time-of-flight ion mobility spectrometry and differential mobility spectrometry: A comparative study of their efficiency in the analysis of halogenated compounds

Talanta ◽

10.1016/j.talanta.2006.08.017 ◽

2007 ◽

Vol 71 (4) ◽

pp. 1804-1812 ◽

Cited By ~ 22

Author(s):

H. Borsdorf ◽

E.G. Nazarov ◽

R.A. Miller

Keyword(s):

Comparative Study ◽

Ion Mobility Spectrometry ◽

Ion Mobility ◽

Time Of Flight ◽

Differential Mobility Spectrometry ◽

Halogenated Compounds ◽

Differential Mobility

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FIELD INDUCED DISPLACEMENT REACTIONS WITH PROTON BOUND DIMERS OF ORGANOPHOSPHORUS COMPOUNDS IN A TANDEM DIFFERENTIAL MOBILITY SPECTROMETER

The Analyst ◽

10.1039/d1an00783a ◽

2021 ◽

Author(s):

Peter E. Fowler ◽

Jacob Zachary Pilgrim ◽

Marlen Menlyadiev ◽

Gary A Eiceman

Keyword(s):

Organophosphorus Compounds ◽

Ambient Pressure ◽

Differential Mobility Spectrometry ◽

Differential Mobility ◽

Differential Mobility Spectrometer ◽

Displacement Reactions

Endothermic displacement reactions between proton bound dimers of organophosphorus compounds (OPCs) and isopropanol (IPA) were enabled in air at ambient pressure with tandem differential mobility spectrometry (DMS). Proton bound dimers...

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Hyphenated differential mobility spectrometry for rapid separation and detection

Reviews in Analytical Chemistry ◽

10.1515/revac-2015-0017 ◽

2016 ◽

Vol 35 (1) ◽

pp. 29-40

Author(s):

Liu Yang ◽

Qiang Han ◽

Shuya Cao ◽

Junchao Yang ◽

Jiang Zhao ◽

...

Keyword(s):

Ion Mobility ◽

Chemical Warfare Agents ◽

Chemical Warfare ◽

Differential Mobility Spectrometry ◽

Real Field ◽

Asymmetric Waveform ◽

Differential Mobility ◽

Rapid Separation ◽

Volatile Organic ◽

Warfare Agents

AbstractThis paper reviews hyphenated differential mobility spectrometry (DMS) technology. DMS is a type of ion mobility spectrometry (IMS) also called high-field asymmetric waveform IMS. It is widely used in the detection of chemical warfare agents, explosives, drugs, and volatile organic compounds. Stand-alone DMS analysis of complex mixtures in real-field applications is challenging. Hyphenated DMS can improve resolution for rapid separation and detection. This review focuses on hyphenated DMS, including gas chromatography-DMS, DMS-mass spectrometry (MS), DMS-IMS, IMS-DMS, and DMS-DMS, as well as their associated principles, applications, and research procedures. Key problems in hyphenated DMS are considered.

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Gas phase fragmentation of protonated esters in air at ambient pressure through ion heating by electric field in differential mobility spectrometry

International Journal of Mass Spectrometry ◽

10.1016/j.ijms.2011.01.031 ◽

2011 ◽

Vol 303 (2-3) ◽

pp. 181-190 ◽

Cited By ~ 20

Author(s):

X. An ◽

G.A. Eiceman ◽

J.E. Rodriguez ◽

J.A. Stone

Keyword(s):

Electric Field ◽

Gas Phase ◽

Ambient Pressure ◽

Differential Mobility Spectrometry ◽

Differential Mobility ◽

Ion Heating ◽

Gas Phase Fragmentation

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Clustering and Nonclustering Modifier Mixtures in Differential Mobility Spectrometry for Multidimensional Liquid Chromatography Ion Mobility–Mass Spectrometry Analysis

Analytical Chemistry ◽

10.1021/acs.analchem.0c04889 ◽

2021 ◽

Vol 93 (17) ◽

pp. 6638-6645

Author(s):

David Ruskic ◽

Frank Klont ◽

Gérard Hopfgartner

Keyword(s):

Mass Spectrometry ◽

Liquid Chromatography ◽

Ion Mobility ◽

Differential Mobility Spectrometry ◽

Mass Spectrometry Analysis ◽

Ion Mobility Mass Spectrometry ◽

Differential Mobility ◽

Spectrometry Analysis

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Differential Mobility Spectrometry of Isomeric Protonated Dipeptides: Modifier and Field Effects on Ion Mobility and Stability

Analytical Chemistry ◽

10.1021/ac200100s ◽

2011 ◽

Vol 83 (9) ◽

pp. 3470-3476 ◽

Cited By ~ 42

Author(s):

Voislav Blagojevic ◽

Alexander Chramow ◽

Bradley B. Schneider ◽

Thomas R. Covey ◽

Diethard K. Bohme

Keyword(s):

Ion Mobility ◽

Differential Mobility Spectrometry ◽

Differential Mobility ◽

Field Effects

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Fragmentation, auto-modification and post ionisation proton bound dimer ion formation: the differential mobility spectrometry of low molecular weight alcohols

The Analyst ◽

10.1039/c6an00435k ◽

2016 ◽

Vol 141 (15) ◽

pp. 4587-4598 ◽

Cited By ~ 7

Author(s):

D. M. Ruszkiewicz ◽

C. L. P. Thomas ◽

G. A. Eiceman

Keyword(s):

Molecular Weight ◽

Atmospheric Pressure ◽

Differential Mobility Spectrometry ◽

Low Molecular Weight ◽

Differential Mobility ◽

Ion Formation ◽

Proton Bound Dimer ◽

Enhanced Selectivity

Ion-neutral interactions at atmospheric pressure result in significant complexity in the observed responses for alcohols by differential mobility spectrometry. Such behaviours ultimately enable enhanced selectivity and confidence in data assignments.

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