Plasmonic enhanced enzyme activity by catalytic cascade induced mutual benefit tumor starvation/immune/photothermal therapy

2021 ◽  
Author(s):  
Xin Cheng ◽  
Zining Hao ◽  
Shuzhen Chu ◽  
Tiantian Zhang ◽  
Cong Cong ◽  
...  
Keyword(s):  
Enzyme Activity ◽  
Tumor Cell ◽  
Signaling Pathways ◽  
Tumor Cells ◽  
Photothermal Therapy ◽  
Mutual Benefit ◽  
Cell Metastasis ◽  
Tumor Cell Metastasis ◽  
Single Tumor

Single tumor starvation therapy can activate other signaling pathways in tumor cells and easily induce tumor cell metastasis.

scholarly journals Continuous Endoglin (CD105) Overexpression Disrupts Angiogenesis and Facilitates Tumor Cell Metastasis

2019 ◽  
Author(s):  
Claudia Ollauri-Ibáñez ◽  
Elena Núñez-Gómez ◽  
Cristina Egido-Turrión ◽  
Laura Silva-Sousa ◽  
Alicia Rodríguez-Barbero ◽  
...  
Keyword(s):  
Tumor Growth ◽  
Tumor Cell ◽  
Tumor Cells ◽  
Subsequent Development ◽  
Cancer Prognosis ◽  
Cancer Disease ◽  
Mural Cells ◽  
Complex Process ◽  
Cell Metastasis ◽  
Tumor Cell Metastasis

ABSTRACTAngiogenesis is a complex process essential for tumor growth. For this reason, high levels of pro-angiogenic molecules, such as endoglin (CD105), are supposed to be related to greater tumor growth that lead to a poor cancer prognosis. However, we demonstrate here that defects in angiogenesis that can be attributed to high levels of endoglin, lead to development and worsening of cancer disease. Steady endoglin overexpression disrupts the correct stabilization of the endothelium and the recruitment of mural cells. In consequence, endoglin overexpression gives rise to altered vessels that promote the intravasation of tumor cells, the subsequent development of metastases and, thus, a worse cancer prognosis.

Enhanced Endothelial Cell Retraction Mediated by 12(S)-HETE: A Proposed Mechanism for the Role of Platelets in Tumor Cell Metastasis

1994 ◽  
Vol 210 (1) ◽  
pp. 1-9 ◽  
Author(s):  
Kenneth V. Honn ◽  
Dean G. Tang ◽  
Irma M. Grossi ◽  
Colette Renaud ◽  
Zofia M. Duniec ◽  
...  
Keyword(s):  
Endothelial Cell ◽  
Tumor Cell ◽  
Cell Metastasis ◽  
Tumor Cell Metastasis ◽  
Endothelial Cell Retraction ◽  
Cell Retraction

Diets Rich in Fish Oil Cannot Control Tumor Cell Metastasis

1987 ◽  
Vol 31 (6) ◽  
pp. 342-348 ◽  
Author(s):  
Will J. Kort ◽  
Ineke M. Weijma ◽  
Toos E.M. Stehmann ◽  
Antoine J. Vergroesen ◽  
Dick L. Westbroek
Keyword(s):  
Tumor Cell ◽  
Fish Oil ◽  
Cell Metastasis ◽  
Tumor Cell Metastasis ◽  
Control Tumor
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