Sequence-Selective Recognition of Cationic Amphipathic Tripeptides with Similar Structures in Aqueous Solution by Cucurbit[7]uril

Author(s):  
Fenfen Ma ◽  
Xiaoyan Zheng ◽  
Ze-Sheng Li

The sequence-selective recognition of cationic amphipathic peptides by synthetic receptors is significant to biological applications, but it is still a great challenge. Here we firstly study the binding characteristics of...

Molecules ◽  
2020 ◽  
Vol 26 (1) ◽  
pp. 106
Author(s):  
Joana N. Martins ◽  
João Carlos Lima ◽  
Nuno Basílio

To this day, the recognition and high affinity binding of biomolecules in water by synthetic receptors remains challenging, while the necessity for systems for their sensing, transport and modulation persists. This problematic is prevalent for the recognition of peptides, which not only have key roles in many biochemical pathways, as well as having pharmacological and biotechnological applications, but also frequently serve as models for the study of proteins. Taking inspiration in nature and on the interactions that occur between several receptors and peptide sequences, many researchers have developed and applied a variety of different synthetic receptors, as is the case of macrocyclic compounds, molecular imprinted polymers, organometallic cages, among others, to bind amino acids, small peptides and proteins. In this critical review, we present and discuss selected examples of synthetic receptors for amino acids and peptides, with a greater focus on supramolecular receptors, which show great promise for the selective recognition of these biomolecules in physiological conditions. We decided to focus preferentially on small synthetic receptors (leaving out of this review high molecular weight polymeric systems) for which more detailed and accurate molecular level information regarding the main structural and thermodynamic features of the receptor biomolecule assemblies is available.


Polyhedron ◽  
2006 ◽  
Vol 25 (17) ◽  
pp. 3366-3378 ◽  
Author(s):  
Agostinho Cachapa ◽  
Alfredo Mederos ◽  
Pedro Gili ◽  
Rita Hernández-Molina ◽  
Sixto Domínguez ◽  
...  

2019 ◽  
Vol 17 (10) ◽  
pp. 2825-2825 ◽  
Author(s):  
Ananya Dutta ◽  
Abu Saleh Musha Islam ◽  
Debjani Maiti ◽  
Mihir Sasmal ◽  
Chandraday Prodhan ◽  
...  

Correction for ‘A smart molecular probe for selective recognition of nitric oxide in 100% aqueous solution with cell imaging application and DFT studies’ by Ananya Dutta et al., Org. Biomol. Chem., 2019, DOI: 10.1039/c9ob00177h.


2020 ◽  
Vol 2020 (30) ◽  
pp. 4681-4692
Author(s):  
Ergin Keleş ◽  
Burcu Aydıner ◽  
Yahya Nural ◽  
Nurgül Seferoğlu ◽  
Ertan Şahin ◽  
...  

2019 ◽  
Vol 220 ◽  
pp. 03033
Author(s):  
Dmitrii Zharkov ◽  
Andrey Leontyev ◽  
Artemii Smelev ◽  
Victor Nikiforov ◽  
Vladimir Lobkov ◽  
...  

Using the hydrothermal method, we synthesized water soluble YVO4: Yb, Er nanoparticles with a size less than 10 nm. Nanoparticles exhibit intense luminescence in the green region due to Er3+ ions when excited by laser radiation at a wavelength of 980 nm as a result of the up-conversion process. Bright and stable luminescence also persists in an aqueous solution of nanoparticles. Based on experimental data, it can be argued that the objects obtained are promising in biological applications, as well as up-conversion phosphors.


2009 ◽  
Vol 74 (20) ◽  
pp. 7943-7946 ◽  
Author(s):  
Yimin Sun ◽  
Cheng Zhong ◽  
Rui Gong ◽  
Honglei Mu ◽  
Enqin Fu

RSC Advances ◽  
2016 ◽  
Vol 6 (111) ◽  
pp. 110019-110031 ◽  
Author(s):  
Xumian Gao ◽  
Xiaoling Hu ◽  
Ping Guan ◽  
Chunbao Du ◽  
Shichao Ding ◽  
...  

Core–shell imprinting microspheres for the selective and rapid recognition of thymopentin with the aid of a novel polymeric ionic liquid.


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