Intake of Lactobacillus rhamnosus GG (LGG) fermented milk before drinking alcohol reduces acetaldehyde levels and duration of flushing in drinkers with wild-type and heterozygous mutant ALDH2: a randomized, blinded crossover controlled trial

2021 ◽  
Author(s):  
Dunyaporn Trachootham ◽  
Kanyawee Whanmek ◽  
Kemika Praengam ◽  
Piya Temviriyanukul ◽  
Chalat Santivarangkna
Keyword(s):  
Alcohol Consumption ◽  
Alcohol Intake ◽  
Controlled Trial ◽  
Lactobacillus Rhamnosus ◽  
Fermented Milk ◽  
Wild Type ◽  
Drinking Alcohol ◽  
Aldehyde Dehydrogenase 2 ◽  
Lactobacillus Rhamnosus Gg ◽  
Aldehyde Dehydrogenase 2 Gene

Alcohol consumption leads to acetaldehyde accumulation which is carcinogenic. Drinking LGG fermented milk before alcohol intake reduces blood and salivary acetaldehyde levels especially in people with mutant aldehyde dehydrogenase 2 gene (ALDH2).

scholarly journals The Effects of Alcohol Consumption on Cardiometabolic Health Outcomes Following Weight Loss in Premenopausal Women with Obesity: A Pilot Randomized Controlled Trial

2020 ◽  
Vol 17 (15) ◽  
pp. 5302
Author(s):  
John W. Apolzan ◽  
Robbie A. Beyl ◽  
Corby K. Martin ◽  
Frank L. Greenway ◽  
Ursula White
Keyword(s):  
Weight Loss ◽  
Alcohol Consumption ◽  
Alcohol Intake ◽  
Controlled Trial ◽  
Pilot Trial ◽  
Metabolic Effects ◽  
Cardiometabolic Health ◽  
Moderate Alcohol Consumption ◽  
Randomized Controlled ◽  
Metabolic Outcomes

Alcohol (i.e., ethanol) is consumed regularly by much of the adult population; yet, the health effects associated with its use are not well-characterized. Clinical interventions to investigate the effects of moderate alcohol consumption on metabolic outcomes, including adiposity and cardiovascular risk factors, are limited and have yielded conflicting data. In addition, no study has reported the effects of routine alcohol intake during weight loss in a controlled feeding trial. We present the first randomized controlled pilot trial to investigate the effects of moderate alcohol consumption on metabolic outcomes during weight loss in women with obesity. Both groups consumed 30% energy restricted diets and were randomized to either an ethanol-free control (CTL) group or a group (EtOH) that consumed 35 g ethanol daily for eight weeks. Our findings demonstrate that, despite similar weight loss, the decrease in mean arterial pressure was attenuated in the EtOH group, relative to the CTL group (p = 0.02). In addition, decreases in other outcomes, including visceral adipose tissue (p = 0.23), circulating lipids (triglycerides (p = 0.11) and cholesterol (p = 0.11)), and uric acid (p = 0.07) tended to be attenuated with alcohol consumption. These pilot data provide potential evidence that moderate alcohol consumption may mitigate the beneficial effects of weight loss and support the need for larger Randomized Controlled Trials (RCTs) to better investigate the metabolic effects of moderate alcohol intake in humans.

scholarly journals Probiotic Lactobacillus rhamnosus GG therapy and microbiological programming in infantile colic: a randomized, controlled trial

2015 ◽  
Vol 78 (4) ◽  
pp. 470-475 ◽  
Author(s):  
Anna Pärtty ◽  
Liisa Lehtonen ◽  
Marko Kalliomäki ◽  
Seppo Salminen ◽  
Erika Isolauri
Keyword(s):  
Randomized Controlled Trial ◽  
Controlled Trial ◽  
Lactobacillus Rhamnosus ◽  
Infantile Colic ◽  
Lactobacillus Rhamnosus Gg ◽  
Randomized Controlled ◽  
Probiotic Lactobacillus

Randomized, placebo-controlled trial of Lactobacillus rhamnosus GG as treatment of atopic dermatitis in infancy

Allergy ◽  
2007 ◽  
Vol 62 (11) ◽  
pp. 1270-1276 ◽  
Author(s):  
C. Grüber ◽  
M. Wendt ◽  
C. Sulser ◽  
S. Lau ◽  
M. Kulig ◽  
...  
Keyword(s):  
Atopic Dermatitis ◽  
Controlled Trial ◽  
Lactobacillus Rhamnosus ◽  
Lactobacillus Rhamnosus Gg

Efficacy of Lactobacillus rhamnosus GG in acute watery diarrhoea of Indian children: A randomised controlled trial

2007 ◽  
Vol 43 (12) ◽  
pp. 837-842 ◽  
Author(s):  
Sriparna Basu ◽  
Mridula Chatterjee ◽  
Sutapa Ganguly ◽  
Pranab K Chandra
Keyword(s):  
Randomised Controlled Trial ◽  
Controlled Trial ◽  
Lactobacillus Rhamnosus ◽  
Watery Diarrhoea ◽  
Indian Children ◽  
Lactobacillus Rhamnosus Gg ◽  
Randomised Controlled

P.09.10: A Randomized, Double Blind Controlled Trial on the Effect of Lactobacillus Rhamnosus GG in Patients with Minimal Hepatic Encephalopathy

2017 ◽  
Vol 49 ◽  
pp. e191
Author(s):  
E. Shahini ◽  
M. Barone ◽  
A. Iannone ◽  
M.T. Viggiani ◽  
V. Corvace ◽  
...  
Keyword(s):  
Hepatic Encephalopathy ◽  
Controlled Trial ◽  
Lactobacillus Rhamnosus ◽  
Minimal Hepatic Encephalopathy ◽  
Lactobacillus Rhamnosus Gg ◽  
Double Blind
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