Metal-free reduction of unsaturated carbonyls, quinones, and pyridinium salts with tetrahydroxydiboron/water

2021 ◽  
Author(s):  
Henian Peng ◽  
Tiejun Li ◽  
Duanshuai Tian ◽  
He Yang ◽  
Guangqing Xu ◽  
...  
Keyword(s):  
Pyridinium Salts ◽  
Metal Free ◽  
Unsaturated Carbonyls ◽  
High Yields

Tetrahydroxydiboron/water effectively reduce a series of unsaturated carbonyls, quinones, and pyridinium salts to the corresponding saturated carbonyls, dihydroxybenzenes, and hydropyridines in moderate to high yields.

Cinchona alkaloid and di-tert-butyldicarbonate–DMAP promoted efficient synthesis of (E)-nitroolefins

RSC Advances ◽  
2016 ◽  
Vol 6 (59) ◽  
pp. 54495-54502 ◽  
Author(s):  
Nataraj Poomathi ◽  
Paramasivan T. Perumal
Keyword(s):  
Cinchona Alkaloid ◽  
Efficient Synthesis ◽  
Metal Free ◽  
High Yields

A simple and efficient metal-free methodology for the synthesis of β-nitroolefins has been developed from arylidinemalononitrile using bifunctional cinchona alkaloid along with di-tert-butyldicarbonate–DMAP in high yields with total selectivity.

A metal-free hydrogenation of 3-substituted 2H-1,4-benzoxazines

2016 ◽  
Vol 14 (34) ◽  
pp. 8026-8029 ◽  
Author(s):  
Simin Wei ◽  
Xiangqing Feng ◽  
Haifeng Du
Keyword(s):  
Metal Free ◽  
High Yields

A metal-free hydrogenation of 3-substituted 2H-1,4-benzoxazines was realized to furnish the desired products in high yields with up to 42% ee.

Synthesis of functionalized 3-isochromanones via metal-free intramolecular alkoxylation-initiated cascade cyclization

2019 ◽  
Vol 21 (11) ◽  
pp. 3023-3028 ◽  
Author(s):  
Ying-Qi Zhang ◽  
Xin-Qi Zhu ◽  
Yin Xu ◽  
Hao-Zhen Bu ◽  
Jia-Le Wang ◽  
...  
Keyword(s):  
Allyl Ether ◽  
Metal Free ◽  
Cascade Cyclization ◽  
High Yields

A metal-free intramolecular alkoxylation-initiated cascade cyclization of allyl ether-tethered ynamides has been developed, leading to functionalized 3-isochromanones in high yields.

A Convenient Synthesis of 1,5-Fused 1,2,4-Triazoles from N-Arylamidines via Chloramine-T Mediated Intramolecular Oxidative N–N Bond Formation

Synthesis ◽  
2019 ◽  
Vol 51 (20) ◽  
pp. 3883-3890
Author(s):  
Ashish Bhatt ◽  
Rajesh K. Singh ◽  
Ravi Kant ◽  
Bhupendra K. Sarma
Keyword(s):  
Reaction Time ◽  
Bond Formation ◽  
Available N ◽  
Short Reaction Time ◽  
Metal Free ◽  
Convenient Synthesis ◽  
Chloramine T ◽  
High Yields ◽  
Short Time

A convenient synthesis of 1,5-fused 1,2,4-triazoles from readily available N-arylamidines is reported. The reaction is efficiently promoted by chloramine-T to afford the desired products mostly in high yields and in relatively short time, through direct metal-free oxidative N−N bond formation. The mild nature of the synthesis and short reaction time are notable advantages of the developed protocol. This protocol is effective toward various substrates having different functionalities.

Metal-free switchable ortho/ipso-cyclization of N-aryl alkynamides: divergent synthesis of 3-selenyl quinolin-2-ones and azaspiro[4,5]trienones

2019 ◽  
Vol 17 (48) ◽  
pp. 10163-10166 ◽  
Author(s):  
Harekrishna Sahoo ◽  
Gowri Sankar Grandhi ◽  
Isai Ramakrishna ◽  
Mahiuddin Baidya
Keyword(s):  
Metal Free ◽  
High Yields

A selenium radical triggered switchable ortho/ipso-cyclization cascade of N-aryl alkynamides has been devised under metal-free conditions to access 3-selenyl quinolin-2-ones and 3-selenospiro[4,5]trienones in high yields (up to 98%).

A photo-auxiliary approach – enabling excited state classical phototransformations with metal free visible light irradiation

2017 ◽  
Vol 53 (10) ◽  
pp. 1692-1695 ◽  
Author(s):  
Akila Iyer ◽  
Steffen Jockusch ◽  
Jayaraman Sivaguru
Keyword(s):  
Excited State ◽  
Visible Light ◽  
Visible Light Irradiation ◽  
Uv Light ◽  
Light Irradiation ◽  
Metal Free ◽  
High Yields

To address the problem of using UV light to initiate traditional photoreactions, hydrazide based chromophores are evaluated as a “photo-auxiliary“ with visible light using a metal free photocatalyst to afford photoproducts in high yields.

Borane-catalyzed metal-free hydrogenation of 2,7-disubstituted 1,8-naphthyridines

2016 ◽  
Vol 14 (28) ◽  
pp. 6683-6686 ◽  
Author(s):  
Wei Wang ◽  
Xiangqing Feng ◽  
Haifeng Du
Keyword(s):  
Metal Free ◽  
High Yields

Metal-free hydrogenation of 2,7-disubstituted 1,8-naphthyridines was realized to furnish 1,2,3,4-tetrahydro-1,8-naphthyridines in high yields with up to 74% ee.

Metal free visible light driven oxidation of alcohols to carbonyl derivatives using 3,6-di(pyridin-2-yl)-1,2,4,5-tetrazine (pytz) as catalyst

RSC Advances ◽  
2015 ◽  
Vol 5 (102) ◽  
pp. 84328-84333 ◽  
Author(s):  
Suvendu Samanta ◽  
Papu Biswas
Keyword(s):  
Visible Light ◽  
Visible Light Irradiation ◽  
Room Temperature ◽  
Light Irradiation ◽  
Metal Free ◽  
Carbonyl Derivatives ◽  
Oxidation Of Alcohols ◽  
Visible Light Driven ◽  
High Yields

A metal-free transformation of alcohols to the corresponding carbonyls in high yields under visible-light irradiation has been achieved at room temperature using di(pyridin-2-yl)-1,2,4,5-tetrazine (pytz) as catalyst.

Stereoselective organocatalysed reactions in deep eutectic solvents: highly tunable and biorenewable reaction media for sustainable organic synthesis

2016 ◽  
Vol 18 (3) ◽  
pp. 792-797 ◽  
Author(s):  
Elisabetta Massolo ◽  
Silvia Palmieri ◽  
Maurizio Benaglia ◽  
Vito Capriati ◽  
Filippo M. Perna
Keyword(s):  
Organic Synthesis ◽  
Environmentally Friendly ◽  
Deep Eutectic Solvents ◽  
Chiral Catalyst ◽  
Metal Free ◽  
Extraction Protocol ◽  
Enantioselective Reactions ◽  
Simple Extraction ◽  
High Yields ◽  
Reaction Media

Different metal-free catalytic enantioselective reactions have been performed in high yields and enantioselectivity in natural, biorenewable and environmentally-friendly DESs. The recyclability of the chiral catalyst by a simple extraction protocol was also successfully accomplished.

Rapid and efficient synthesis of metal-free phthalocyanine derivatives

2006 ◽  
Vol 10 (11) ◽  
pp. 1253-1258 ◽  
Author(s):  
Ahmad Shaabani ◽  
Ali Maleki
Keyword(s):  
Ionic Liquid ◽  
Microwave Irradiation ◽  
Phase Transfer ◽  
Tetrabutylammonium Bromide ◽  
Efficient Synthesis ◽  
Metal Free ◽  
High Yields ◽  
Short Times

Metal-free phthalocyanine derivatives have been synthesized in very short times with high yields in the presence of 1,1,3,3-tetramethylguanidinium trifluoroacetate (TMGT) as an ionic liquid or tetrabutylammonium bromide (TBAB) as a phase transfer reagent under both classical heating conditions and using microwave irradiation. The best results were obtained with ionic liquid. Both the ionic liquid and phase transfer reagent can be recycled for subsequent reactions and reused without appreciable loss of efficiency.

Sign in / Sign up

Export Citation Format

Share Document