scholarly journals Polymers as advanced antibacterial and antibiofilm agents for direct and combination therapies

2022 ◽  
Author(s):  
Zhangyong Si ◽  
Wenbin Zhong ◽  
Dicky Pranantyo ◽  
Jianghua Li ◽  
CHONG HUI KOH ◽  
...  

The growing prevalence of antimicrobial drug resistance in pathogenic bacteria is a critical threat to global health. Conventional antibiotics still play a crucial role in treating bacterial infections, but the...

2021 ◽  
Vol 12 (2) ◽  
pp. 78
Author(s):  
RamakrishnaJakribettu Pai ◽  
ManjeshwarShrinath Baliga ◽  
NikkuMathew Geevarughese ◽  
Siddhant Suresh ◽  
JeffyMary Mathew ◽  
...  

1990 ◽  
Vol 22 (2) ◽  
pp. 197-203 ◽  
Author(s):  
Ali A. Farhoudi-Moghaddam ◽  
Mohammad Katouli ◽  
Anis Jafari ◽  
Mohammad A. Bahavar ◽  
Mostafa Parsi ◽  
...  

2011 ◽  
Vol 17 (10) ◽  
pp. 1879-1882 ◽  
Author(s):  
Uwe Groß ◽  
Sylvarius K. Amuzu ◽  
Ring de Ciman ◽  
Iparkhan Kassimova ◽  
Lisa Groß ◽  
...  

Author(s):  
Silas O. Awuor ◽  
Eric O. Omwenga ◽  
Ibrahim I. Daud

Background: Multiple drug resistance has become a major threat to the treatment of cholera. Recent studies in Kenya have described the epidemiology, especially the risk factors, of cholera; however, there is little information on the phenotypic and drug susceptibility patterns of Vibrio cholerae (V. cholerae) in outbreaks that in the recent past have occurred in western Kenya.Aim: To characterise and determine the antibiotics’ susceptibility profiling of toxigenic V. cholerae isolates from Kisumu County.Setting: The project was conducted in Kisumu County, Kenya.Methods: A total of 119 V. cholerae O1, biotype El Tor, isolates collected during 2017 cholera outbreak in Kisumu County were used for this study. The samples were cultured on thiosulphate-citrate-bile salts sucrose (TCBS) agar and biochemical tests were carried out using standard procedures. Susceptibility tests were conducted by using various conventional antibiotics against standard procedures.Results: Of the 119 isolates, 101 were confirmed to be V. cholerae belonging to serotypes Inaba and Ogawa, with Inaba being the predominant serotype (73.95%). The isolates were susceptible to ciprofloxacin (100%), ofloxacin (100%), gentamycin (100%), doxycycline (99%), ceftriaxone (99%) and streptomycin (96.04%) antimicrobials, and resistant to erythromycin (53.47%), amoxicillin (64.4%), nalidixic acid (83.2%) and ampicillin (89.11%), with high resistance to cotrimoxazole (99%) and tetracycline (97%).Conclusion: Vibrio cholerae was resistant to multiple antibiotics, including those commonly used in the management of cholera. Taken together, there is a need to carry out regular surveillance on antimicrobial drug resistance during outbreaks.


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