Vitamin K-dependent protein S is similar to rat androgen-binding protein
Keyword(s):
Vitamin K-dependent protein S belongs to the family of clotting factors (e.g. Factors IX and X, and protein C). Unlike the other clotting factors, the C-terminal half (residues 250-634) of protein S is not a serine proteinase. In fact, the function of residues 250-634 of protein S is unknown. By using computer programs designed to detect evolutionary relationships between proteins, we find that this part of protein S is similar to rat androgen-binding protein, a protein produced and secreted by testicular Sertoli cells. The homology between protein S and androgen-binding protein suggests new approaches for elucidating their functions.
Keyword(s):
1981 ◽
Vol 78
(4)
◽
pp. 2512-2516
◽
1990 ◽
Vol 265
(27)
◽
pp. 16082-16087
◽
Keyword(s):
2002 ◽
Vol 169
(5)
◽
pp. 2580-2586
◽
Keyword(s):
Keyword(s):
2002 ◽
Vol 66
(4)
◽
pp. 877-885
◽
1984 ◽
Vol 10
(02)
◽
pp. 139-148
◽
1988 ◽
Vol 68
(4)
◽
pp. 445-449
◽
Keyword(s):