The major phosphorylation site of nucleophosmin (B23) is phosphorylated by a nuclear kinase II
Keyword(s):
Type Ii
◽
Nucleophosmin (B23) was phosphorylated in vitro with [gamma-32P]ATP and a nuclear kinase (type II) purified from HeLa cells. The phosphorylation was inhibited by heparin and by 2,3-diphosphoglycerate. Peptide mapping analysis indicated that the phosphorylation site in vitro was identical to that in vivo. Purified nucleoli have a similar kinase that phosphorylated nucleophosmin at the same site. These results indicated that nucleophosmin is phosphorylated in vivo by a nucleolar kinase (type II).
2005 ◽
Vol 25
(4)
◽
pp. 1446-1457
◽
1983 ◽
Vol 258
(7)
◽
pp. 4440-4446
◽
Keyword(s):
1995 ◽
Vol 131
(5)
◽
pp. 1291-1301
◽
Keyword(s):
2006 ◽
Vol 26
(3)
◽
pp. 965-975
◽
2003 ◽
Vol 23
(8)
◽
pp. 2953-2968
◽
2015 ◽
Vol 42
(7)
◽
pp. 1042-1049
◽
1991 ◽
Vol 145
(1-2)
◽
pp. 213-221
◽