A novel antioxidant action of ethanolamine plasmalogens in lowering the oxidizability of membranes

2004 ◽  
Vol 32 (1) ◽  
pp. 141-143 ◽  
Author(s):  
R. Maeba ◽  
N. Ueta
Keyword(s):  
Free Radicals ◽  
Oxygen Uptake ◽  
Water Soluble ◽  
Antioxidant Action ◽  
Unilamellar Vesicles ◽  
Radical Initiator ◽  
Large Unilamellar Vesicles ◽  
Ethanolamine Plasmalogens ◽  
Uptake Method

We have demonstrated a novel antioxidant action of ethanolamine plasmalogens both in protecting cholesterol from oxidation by free radicals and in lowering the oxidizability of membranes, along with the action of scavenging radicals, by the oxygen-uptake method using large unilamellar vesicles and the water-soluble azo-radical initiator, AAPH [2,2´-azobis-(2-amidino-propane) dihydrochloride].

scholarly journals Asymmetric reassociation of calf spleen NAD+ glycohydrolase into liposomes

1987 ◽  
Vol 246 (2) ◽  
pp. 319-324 ◽  
Author(s):  
H M Muller ◽  
F Schuber
Keyword(s):  
Outer Surface ◽  
Active Site ◽  
Gel Filtration ◽  
Water Soluble ◽  
Unilamellar Vesicles ◽  
Phosphatidylcholine Liposomes ◽  
Nad Glycohydrolase ◽  
Large Unilamellar Vesicles ◽  
Solubilized Enzyme

NAD+ glycohydrolase (NAD+ nucleosidase, EC 3.2.2.6) can be solubilized from calf spleen microsomes (microsomal fractions) by steapsin or by detergents to yield respectively a hydrophilic (i.e. water-soluble) and a hydrophobic form of the enzyme. The detergent-solubilized enzyme was successfully reassociated into phosphatidylcholine liposomes either by a cholate-dialysis or by a gel-filtration procedure. In both cases the incorporation of NAD+ glycohydrolase was found to be completely asymmetric, i.e. the active site of the enzyme was exposed only at the outer surface of the vesicles. By contrast, as judged by flotation experiments, the hydrophilic form of NAD+ glycohydrolase could not be reassociated into liposomes. These results are in agreement with the hypothesis that calf spleen NAD+ glycohydrolase is an amphipathic protein. When incorporated into large unilamellar vesicles composed of phosphatidylcholine, NAD+ glycohydrolase was not found to catalyse vectorial transfer of NAD+ by transglycosidation with nicotinamide as acceptor.

scholarly journals Scavenging ability of dendritic PAMAM bridged hindered phenolic antioxidants towards DPPH˙ and ROO˙ free radicals

RSC Advances ◽  
2017 ◽  
Vol 7 (4) ◽  
pp. 1869-1876 ◽  
Author(s):  
Cuiqin Li ◽  
Peng Sun ◽  
Hongyang Yu ◽  
Na Zhang ◽  
Jun Wang
Keyword(s):  
Free Radicals ◽  
Oxygen Uptake ◽  
Tertiary Amine ◽  
Synergistic Effects ◽  
Phenolic Antioxidants ◽  
Dpph Method ◽  
Amine Groups ◽  
Hindered Phenol ◽  
Uptake Method

The intramolecular synergistic effects of two dendritic antioxidants between hindered phenol groups and tertiary amine groups were investigated using the DPPH˙ method and the oxygen uptake method.

scholarly journals α-Synuclein Binds Large Unilamellar Vesicles as an Extended Helix†

Biochemistry ◽  
2009 ◽  
Vol 48 (11) ◽  
pp. 2304-2306 ◽  
Author(s):  
Adam J. Trexler ◽  
Elizabeth Rhoades
Keyword(s):  
Unilamellar Vesicles ◽  
Large Unilamellar Vesicles

Evolution of the thermotropic properties of large unilamellar vesicles (LUV)

1984 ◽  
Vol 40 (7) ◽  
pp. 715-717 ◽  
Author(s):  
M. Vandenbranden ◽  
C. Stil ◽  
R. Brasseur ◽  
J. -M. Ruysschaert
Keyword(s):  
Unilamellar Vesicles ◽  
Large Unilamellar Vesicles ◽  
Thermotropic Properties

The Efficacies of Cell-Penetrating Peptides in Accumulating in Large Unilamellar Vesicles Depend on their Ability To Form Inverted Micelles

ChemBioChem ◽  
2014 ◽  
Vol 15 (6) ◽  
pp. 884-891 ◽  
Author(s):  
Jean-Marie Swiecicki ◽  
Annika Bartsch ◽  
Julien Tailhades ◽  
Margherita Di Pisa ◽  
Benjamin Heller ◽  
...  
Keyword(s):  
Cell Penetrating Peptides ◽  
Unilamellar Vesicles ◽  
Large Unilamellar Vesicles ◽  
Cell Penetrating
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